ChemicalBook >> CAS DataBase List >>SKL 2001
SKL 2001
- CAS No.
- 909089-13-0
- Chemical Name:
- SKL 2001
- Synonyms
- 2001;CS-2771;SKL 2001;SKL2001 free base;SKL-2001;SKL 2001;SKL2001;SKL-2001;SKL 2001;N-(3-(1H-imidazol-1-yl)propyl)-5-(furan-2-yl)isoxazole-3-carboxamide;3-Isoxazolecarboxamide, 5-(2-furanyl)-N-[3-(1H-imidazol-1-yl)propyl]-;Inhibitor,SKL-2001,Wnt,Beta catenin,SKL2001,SKL 2001,β-catenin,inhibit;5-(furan-2-yl)-N-[3-(1H-imidazol-1-yl)propyl]-1,2-oxazole-3-carboxamide
- CBNumber:
- CB33146382
- Molecular Formula:
- C14H14N4O3
- Molecular Weight:
- 286.29
- MDL Number:
- MFCD14733081
- MOL File:
- 909089-13-0.mol
Last updated:2023-06-08 09:03:09
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H302-H315-H319-H335 | |||||||||
| Precautionary statements | P261-P264-P270-P271-P280-P301+P312-P330-P302+P352-P321-P304+P340-P305+P351+P338-P332+P313-P362+P364-P337+P313-P403+P233-P405-P501 | |||||||||
| NFPA 704 |
|
SKL 2001 price More Price(18)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Cayman Chemical | 26334 | SKL2001 | 909089-13-0 | 5mg | $49 | 2024-03-01 | Buy |
| Cayman Chemical | 26334 | SKL2001 | 909089-13-0 | 10mg | $92 | 2024-03-01 | Buy |
| Cayman Chemical | 26334 | SKL2001 | 909089-13-0 | 25mg | $216 | 2024-03-01 | Buy |
| Cayman Chemical | 26334 | SKL2001 | 909089-13-0 | 100mg | $665 | 2024-03-01 | Buy |
| ChemScene | CS-0020797 | SKL2001 99.54% | 909089-13-0 | 100mg | $520 | 2021-12-16 | Buy |
SKL 2001 Chemical Properties,Uses,Production
Description
SKL2001 is an activator of Wnt/β-catenin signaling. It increases β-catenin responsive transcription in a cell-based reporter assay in a concentration-dependent manner, increases β-catenin protein levels in HEK293 cells when used at concentrations of 10 and 30 μM, and disrupts the interaction between Axin and β-catenin. SKL2001 increases alkaline phosphatase (ALP) activity and mineralization in multipotent mesenchymal ST2 cells in a concentration-dependent manner, indicating increased osteoblastogenesis. SKL2001 (40 μM) reduces HCT116 and HT-29 spheroid growth and inhibits proliferation of HCT116 and HT-29 cells. It induces cell cycle arrest at the G0/G1 phase and increases E-cadherin and β-catenin protein levels in HCT116 cells when used at a concentration of 40 μM.
SKL 2001 Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 73)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 32480 | 60 |
| career henan chemical co | +86-0371-86658258 | sales@coreychem.com | China | 29914 | 58 |
| SHANGHAI T&W PHARMACEUTICAL CO., LTD. | +86-021-61551413 +8618813727289 | contact@trustwe.com | China | 5738 | 58 |
| Zhejiang J&C Biological Technology Co.,Limited | +1-2135480471 +1-2135480471 | sales@sarms4muscle.com | China | 10523 | 58 |
| InvivoChem | +1-708-310-1919 +1-13798911105 | sales@invivochem.cn | United States | 6393 | 58 |
| Nantong HI-FUTURE Biology Co., Ltd. | +undefined18051384581 | sales@chemhifuture.com | China | 3136 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354 | support@targetmol.com | United States | 19973 | 58 |
| ShenZhen Trendseen Biological Technology Co.,Ltd. | 13417589054 | trendseenbio@gmail.com | China | 11681 | 58 |
| LEAPCHEM CO., LTD. | +86-852-30606658 | market18@leapchem.com | China | 43348 | 58 |
| Aladdin Scientific | +1-833-552-7181 | sales@aladdinsci.com | United States | 57511 | 58 |
View Lastest Price from SKL 2001 manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2019-09-06 | SKL 2001;N-(3-(1H-imidazol-1-yl)propyl)-5-(furan-2-yl)isoxazole-3-carboxamide
909089-13-0
|
US $1.00 / ASSAYS | 1ASSAYS | 95%~99% | per week:100kg | Career Henan Chemical Co |
-
- SKL 2001;N-(3-(1H-imidazol-1-yl)propyl)-5-(furan-2-yl)isoxazole-3-carboxamide
909089-13-0
- US $1.00 / ASSAYS
- 95%~99%
- Career Henan Chemical Co
SKL 2001
N-(3-(1H-imidazol-1-yl)propyl)-5-(furan-2-yl)isoxazole-3-carboxamide
CS-2771
SKL2001;SKL-2001;SKL 2001
SKL-2001;SKL 2001
5-(furan-2-yl)-N-[3-(1H-imidazol-1-yl)propyl]-1,2-oxazole-3-carboxamide
2001
SKL2001 free base
Inhibitor,SKL-2001,Wnt,Beta catenin,SKL2001,SKL 2001,β-catenin,inhibit
3-Isoxazolecarboxamide, 5-(2-furanyl)-N-[3-(1H-imidazol-1-yl)propyl]-
909089-13-0