ChemicalBook >> CAS DataBase List >>Spiro[2H-furo[2,3-e]isoindole-2,1'(2'H)-naphthalen]-6(3H)-one,3',4',4'a,5',6',7,7',8,8',8'a-decahydro-4,6'-dihydroxy-7-(2-hydroxyethyl)-2',5',5',8'a-tetramethyl-,(1'R,2'R,4'aS,6'R,8'aS)-

Spiro[2H-furo[2,3-e]isoindole-2,1'(2'H)-naphthalen]-6(3H)-one,3',4',4'a,5',6',7,7',8,8',8'a-decahydro-4,6'-dihydroxy-7-(2-hydroxyethyl)-2',5',5',8'a-tetramethyl-,(1'R,2'R,4'aS,6'R,8'aS)-

CAS No.
149598-71-0
Chemical Name:
Spiro[2H-furo[2,3-e]isoindole-2,1'(2'H)-naphthalen]-6(3H)-one,3',4',4'a,5',6',7,7',8,8',8'a-decahydro-4,6'-dihydroxy-7-(2-hydroxyethyl)-2',5',5',8'a-tetramethyl-,(1'R,2'R,4'aS,6'R,8'aS)-
Synonyms
(4aS,8R,8aS)-3,4'-Dihydroxy-7'-(2-hydroxyethyl)-4,4,7,8a-tetramethylspiro[2,3,4a,5,6,7-hexahydro-1H-naphthalene-8,2'-3,8-dihydrofuro [2,3-E]isoindole]-6'-one;Spiro[2H-furo[2,3-e]isoindole-2,1'(2'H)-naphthalen]-6(3H)-one,3',4',4'a,5',6',7,7',8,8',8'a-decahydro-4,6'-dihydroxy-7-(2-hydroxyethyl)-2',5',5',8'a-tetramethyl-,(1'R,2'R,4'aS,6'R,8'aS)-
CBNumber:
CB33193250
Molecular Formula:
C25H35NO5
Molecular Weight:
429.55
MDL Number:
MOL File:
149598-71-0.mol
Last updated:2025-04-17 18:22:24
Product description Number Pack Size Price
Stachybotramide 95+% CD32002373 5mg $990

Spiro[2H-furo[2,3-e]isoindole-2,1'(2'H)-naphthalen]-6(3H)-one,3',4',4'a,5',6',7,7',8,8',8'a-decahydro-4,6'-dihydroxy-7-(2-hydroxyethyl)-2',5',5',8'a-tetramethyl-,(1'R,2'R,4'aS,6'R,8'aS)- Properties

Boiling point 645.3±55.0 °C(Predicted)
Density 1.31±0.1 g/cm3(Predicted)
pka 9.62±0.70(Predicted)

Spiro[2H-furo[2,3-e]isoindole-2,1'(2'H)-naphthalen]-6(3H)-one,3',4',4'a,5',6',7,7',8,8',8'a-decahydro-4,6'-dihydroxy-7-(2-hydroxyethyl)-2',5',5',8'a-tetramethyl-,(1'R,2'R,4'aS,6'R,8'aS)- price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Crysdot CD32002373 Stachybotramide 95+% 149598-71-0 5mg $990 2021-12-16 Buy
Product number Packaging Price Buy
CD32002373 5mg $990 Buy

Spiro[2H-furo[2,3-e]isoindole-2,1'(2'H)-naphthalen]-6(3H)-one,3',4',4'a,5',6',7,7',8,8',8'a-decahydro-4,6'-dihydroxy-7-(2-hydroxyethyl)-2',5',5',8'a-tetramethyl-,(1'R,2'R,4'aS,6'R,8'aS)- Chemical Properties,Uses,Production

Uses

Stachybotramide is a natural fungal metabolite with the property of modulating the activity of cholesteryl ester transfer protein (CETP). Stachybotramide stimulates the transfer of cholesteryl esters (CE) from high-density lipoprotein (HDL) to very-low-density lipoprotein (VLDL) and low-density lipoprotein (LDL), increasing the transfer efficiency by 1.3- to 1.5-fold. Stachybotramide slightly reduced the transfer of cholesteryl esters from LDL and VLDL to HDL at 0.5 mM. The effect of Stachybotramide on the transfer of triglycerides (TG) from HDL was not significant. By these results, Stachybotramide was shown to preferentially stimulate the CETP-mediated transfer of cholesteryl esters from HDL to VLDL and LDL[1].

References

[1] Modulation of the plasma cholesteryl ester transfer by stachybotramide

Spiro[2H-furo[2,3-e]isoindole-2,1'(2'H)-naphthalen]-6(3H)-one,3',4',4'a,5',6',7,7',8,8',8'a-decahydro-4,6'-dihydroxy-7-(2-hydroxyethyl)-2',5',5',8'a-tetramethyl-,(1'R,2'R,4'aS,6'R,8'aS)- Preparation Products And Raw materials

Raw materials

Preparation Products

Spiro[2H-furo[2,3-e]isoindole-2,1'(2'H)-naphthalen]-6(3H)-one,3',4',4'a,5',6',7,7',8,8',8'a-decahydro-4,6'-dihydroxy-7-(2-hydroxyethyl)-2',5',5',8'a-tetramethyl-,(1'R,2'R,4'aS,6'R,8'aS)- Suppliers

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149598-71-0(Spiro[2H-furo[2,3-e]isoindole-2,1'(2'H)-naphthalen]-6(3H)-one,3',4',4'a,5',6',7,7',8,8',8'a-decahydro-4,6'-dihydroxy-7-(2-hydroxyethyl)-2',5',5',8'a-tetramethyl-,(1'R,2'R,4'aS,6'R,8'aS)-)Related Search:

Spiro[2H-furo[2,3-e]isoindole-2,1'(2'H)-naphthalen]-6(3H)-one,3',4',4'a,5',6',7,7',8,8',8'a-decahydro-4,6'-dihydroxy-7-(2-hydroxyethyl)-2',5',5',8'a-tetramethyl-,(1'R,2'R,4'aS,6'R,8'aS)- (4aS,8R,8aS)-3,4'-Dihydroxy-7'-(2-hydroxyethyl)-4,4,7,8a-tetramethylspiro[2,3,4a,5,6,7-hexahydro-1H-naphthalene-8,2'-3,8-dihydrofuro [2,3-E]isoindole]-6'-one 149598-71-0