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fosaprepitant dibenzyl ester

CAS No.
265121-01-5
Chemical Name:
fosaprepitant dibenzyl ester
Synonyms
Fosaprepitant Impurity R;Fosaprepitant Impurity Q;fosaprepitant dibenzyl ester;Fosaprepitant Dimeglumine Dibenzylester Impurity;dibenzyl(3-(((2R,3S)-2-((R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-3-(4-fluorophenyl)morpholino)methyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl)phosphonate;Dibenzyl (3-(((2R,3S)-2-((R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-3-(4-fluorophenyl)morpholino)methyl)-4-ethyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl)phosphonate;Phosphonic acid, P-[3-[[(2R,3S)-2-[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)-4-morpholinyl]methyl]-2,5-dihydro-5-oxo-1H-1,2,4-triazol-1-yl]-, bis(phenylmethyl) ester
CBNumber:
CB34718513
Molecular Formula:
C37H34F7N4O6P
Molecular Weight:
794.65
MDL Number:
MOL File:
265121-01-5.mol
Last updated:2023-04-23 13:52:06

fosaprepitant dibenzyl ester Properties

Melting point >50°C (dec.)
Density 1.42±0.1 g/cm3(Predicted)
storage temp. Hygroscopic, -20°C Freezer, Under inert atmosphere
solubility DMSO (Slightly), Methanol (Slightly)
pka 7.07±0.20(Predicted)
form Solid
color White to Light Yellow
Stability Moisture Sensitive

fosaprepitant dibenzyl ester Chemical Properties,Uses,Production

Uses

Fosaprepitant Dibenzyl Ester is a reactant in the synthetic preparation of phosphorylated morpholine acetal human neurokinin-1 receptor antagonists as water soluble prodrugs.

fosaprepitant dibenzyl ester Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 27)Suppliers
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ATK CHEMICAL COMPANY LIMITED
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Standardpharm Co. Ltd.
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China National Standard Pharmaceutical Corporation Limited
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ChemStrong Scientific Co.,Ltd 0755-0755-66853366 13670046396 sales@chem-strong.com China 17982 56
Shanghai Champ Biopharmaceuticals Co., Ltd. 021-61537865 13585780846 sales@champchem.com China 349 58
Guangzhou Dreampharm Biotechnology Co., Ltd. 17825480238 3008233717@qq.com China 9844 12
Jinan blalong chemical co. LTD 2710913286@.com 1513643261@qq.com China 14253 58
Hefei fuya biotechnology co. LTD 18096409024 sales02@foreversyn.com China 1940 58
Cato Research Chemicals Inc. 020-81215950 4000-868-328 customer@uwalab.com United States 10413 58
Shanghai Haohong Pharmaceutical Co., Ltd. 400-400-8210725 4008210725 malulu@leyan.com China 55023 58
fosaprepitant dibenzyl ester Dibenzyl (3-(((2R,3S)-2-((R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-3-(4-fluorophenyl)morpholino)methyl)-4-ethyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl)phosphonate Fosaprepitant Impurity R Phosphonic acid, P-[3-[[(2R,3S)-2-[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)-4-morpholinyl]methyl]-2,5-dihydro-5-oxo-1H-1,2,4-triazol-1-yl]-, bis(phenylmethyl) ester dibenzyl(3-(((2R,3S)-2-((R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-3-(4-fluorophenyl)morpholino)methyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl)phosphonate Fosaprepitant Impurity Q Fosaprepitant Dimeglumine Dibenzylester Impurity 265121-01-5 C37H34F7N4O6P