ASMI
- CAS No.
- 1850419-05-4
- Chemical Name:
- ASMI
- Synonyms
- ASMI;ASMI >=98% (HPLC)
- CBNumber:
- CB34741553
- Molecular Formula:
- C17H16INO2
- Molecular Weight:
- 393.22
- MDL Number:
- MOL File:
- 1850419-05-4.mol
SAFETY
Risk and Safety Statements
Symbol(GHS) | GHS07 |
---|---|
Signal word | Warning |
Hazard statements | H315-H319-H335 |
Precautionary statements | P305+P351+P338 |
ASMI price More Price(2)
ASMI Chemical Properties,Uses,Production
Biochem/physiol Actions
ASMI is a cell-permeable, non-toxic, biocompatible, photostable, positively charged, mitochondria targeting styryl-methylpyridinium based compound that acts as a rapid, cysteine selective, sensitive, and ratiometric (F 518 /F 452 ?nm) fluorescent turn-on probe (0.5 - 40 μM of [Cys]). Under physiological conditions, cysteine thiol reacts with the ASMI acrylate moiety in a time-dependent manner, and induces a facile intramolecular cyclization to release fluorogenic oxystyryl methylpyridinium. ASMI displays high selectivity over other biothiols (Kobs??= 0.75, 0.038, 0.011 & 0.012 min -1 ?for Cys, Hcy, GSH & Na 2 S, respectively) and with no interference from other biologically relevant amino acids, essential metal ions, and anions, including Na2S. Shown to monitor mitochondrial Cys levels in HeLa cells and in deep tissues (150 μm of penetration depth) by two-photon excited fluorescence microscopy.
ASMI Preparation Products And Raw materials
Raw materials
Preparation Products
ASMI Suppliers
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
TargetMol Chemicals Inc. | +1-781-999-5354 | support@targetmol.com | United States | 19973 | 58 |
Sigma-Aldrich | 021-61415566 800-8193336 | orderCN@merckgroup.com | China | 51471 | 80 |
Energy Chemical | 021-58432009 400-005-6266 | marketing1@energy-chemical.com | China | 44843 | 58 |
Changzhou Furuisi Biotechnology Co., Ltd | 0519-85524369 | 3477467573@qq.com | China | 8618 | 58 |
Supplier | Advantage |
---|---|
TargetMol Chemicals Inc. | 58 |
Sigma-Aldrich | 80 |
Energy Chemical | 58 |
Changzhou Furuisi Biotechnology Co., Ltd | 58 |