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CSLP37 (RIPK2 inhibitor CSLP37)

CAS No.
2244984-64-1
Chemical Name:
CSLP37 (RIPK2 inhibitor CSLP37)
Synonyms
CSLP37;CSLP37 (RIPK2 inhibitor CSLP37);1-Propanesulfonamide, N-[5-[2-amino-5-[4-(1-piperazinyl)phenyl]-3-pyridinyl]-3-fluoro-2-methoxyphenyl]-
CBNumber:
CB34844674
Molecular Formula:
C25H30FN5O3S
Molecular Weight:
499.6
MDL Number:
MOL File:
2244984-64-1.mol
Last updated:2025-04-18 09:52:08

CSLP37 (RIPK2 inhibitor CSLP37) Properties

Boiling point 683.3±65.0 °C(Predicted)
Density 1.295±0.06 g/cm3(Predicted)
pka 7.23±0.10(Predicted)

CSLP37 (RIPK2 inhibitor CSLP37) Chemical Properties,Uses,Production

Uses

CSLP37 is a selective RIPK2 inhibitor with an IC50 of 16.3 nM. CSLP37 shows no inhibitory activity against RIPK1 and RIPK3. CSLP37 displays potent suppression of cellular NOD1 and NOD2 responses[1].

IC 50

RIPK2: 16.3 nM (IC50)

References

[1] Matous Hrdinka, et al. Small molecule inhibitors reveal an indispensable scaffolding role of RIPK2 in NOD2 signaling. EMBO J. 2018 Sep 3;37(17):e99372. DOI:10.15252/embj.201899372

CSLP37 (RIPK2 inhibitor CSLP37) Preparation Products And Raw materials

Raw materials

Preparation Products

CSLP37 (RIPK2 inhibitor CSLP37) Suppliers

Global( 3)Suppliers
Supplier Tel Email Country ProdList Advantage
DC Chemicals 021-58447131 13564518121 doncunbiosci@gmail.com China 544 58
Nantong QuanYi Biotechnology Co., Ltd 0513-66337626 18051384581 sales@chemhifuture.com China 5927 58
Nanjing Shizhou Biology Technology Co.,Ltd 025-85560043 15850508050 cindy.huang@synzest.com China 12000 58
CSLP37 (RIPK2 inhibitor CSLP37) CSLP37 1-Propanesulfonamide, N-[5-[2-amino-5-[4-(1-piperazinyl)phenyl]-3-pyridinyl]-3-fluoro-2-methoxyphenyl]- 2244984-64-1