ChemicalBook >> CAS DataBase List >>GNE-8324
GNE-8324
- CAS No.
- 1698901-76-6
- Chemical Name:
- GNE-8324
- Synonyms
- GNE8324;GNE 8324;GNE-8324;GNE-8324; GNE 8324; GNE8324;4H,6H-Cyclopenta[4,5]thiazolo[3,2-a]pyrimidin-4-one, 2-[[ethyl(4-fluorophenyl)amino]methyl]-7,8-dihydro-;10-{[ethyl(4-fluorophenyl)amino]methyl}-7-thia-1,9-diazatricyclo[6.4.0.02,?]dodeca-2(6),8,10-trien-12-one
- CBNumber:
- CB35582377
- Molecular Formula:
- C18H18FN3OS
- Molecular Weight:
- 343.42
- MDL Number:
- MFCD33029243
- MOL File:
- 1698901-76-6.mol
Last updated:2023-03-31 09:12:59
GNE-8324 price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Biorbyt Ltd | orb611954 | GNE-8324 >98% | 1698901-76-6 | 10mg | $912.9 | 2021-12-16 | Buy |
| ChemScene | CS-0028635 | GNE-8324 | 1698901-76-6 | 25mg | $950 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb611954 | GNE-8324 >98% | 1698901-76-6 | 25mg | $1654.1 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb611954 | GNE-8324 >98% | 1698901-76-6 | 100mg | $2839 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb611955 | GNE-8324 >98% | 1698901-76-6 | 10mg | $3282.7 | 2021-12-16 | Buy |
GNE-8324 Chemical Properties,Uses,Production
Description
GNE-8324 is a potent and selective NMDA receptor PAM.
in vitro
This study showed previously that NMDAR positive allosteric modulator GNE-8324 and M-8324 selectively increase NMDAR activity on the inhibitory neurons and elevates their activity in vitro and in vivo._x000D_ _x000D_ Reference: Front Pharmacol. 2022 Jan 4;12:796179. https://pubmed.ncbi.nlm.nih.gov/35058780/
target
GNE-8324 is a selective GluN2A positive allosteric modulator. GNE-8324 selectively enhances NMDA receptor (NMDAR)-mediated synaptic responses in inhibitory but not excitatory neurons.
GNE-8324 Preparation Products And Raw materials
Raw materials
Preparation Products
GNE-8324 Suppliers
Global( 14)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 32836 | 60 |
| InvivoChem | +1-708-310-1919 +1-13798911105 | sales@invivochem.cn | United States | 6393 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354 | support@targetmol.com | United States | 19973 | 58 |
| Shanghai Lollane Biological Technology Co.,Ltd. | 021-52996696，15000506266 15000506266 | China | 4334 | 55 | |
| ShangHai Biochempartner Co.,Ltd | 17754423994 17754423994 | 2853530910@QQ.com | China | 8014 | 62 |
| Shanghai Rechem science Co., Ltd. | 21-31433387 15618786686 | sales@rechemscience.com | China | 2944 | 58 |
| DC Chemicals | 021-58447131 13564518121 | sales@dcchemicals.com | China | 9412 | 58 |
| Hubei Kele Fine Chemical Co., Ltd | 027-59101668 19945030958 | 2881924765@qq.com | China | 7970 | 58 |
| InvivoChem | 13549236410 | sales@invivochem.cn | China | 6755 | 58 |
| Wuhan Yingnuo Pharmaceutical Technology Co., Ltd. | +86-027-59232304 15387063101 | 2881924050@qq.com | China | 9967 | 58 |
GNE 8324
GNE8324
GNE-8324
GNE-8324; GNE 8324; GNE8324
4H,6H-Cyclopenta[4,5]thiazolo[3,2-a]pyrimidin-4-one, 2-[[ethyl(4-fluorophenyl)amino]methyl]-7,8-dihydro-
10-{[ethyl(4-fluorophenyl)amino]methyl}-7-thia-1,9-diazatricyclo[6.4.0.02,?]dodeca-2(6),8,10-trien-12-one
1698901-76-6