[2H6]-Sotalol
![[2H6]-Sotalol Structure](CAS/20211123/GIF/1246912-17-3.gif)
- CAS No.
- 1246912-17-3
- Chemical Name:
- [2H6]-Sotalol
- Synonyms
- [2H6]-Sotalol
- CBNumber:
- CB38011788
- Molecular Formula:
- C12H20N2O3S
- Molecular Weight:
- 272.36
- MDL Number:
- MOL File:
- 1246912-17-3.mol
[2H6]-Sotalol Chemical Properties,Uses,Production
Uses
Sotalol-d6 is the deuterium labeled Sotalol. Sotalol is an orally active, non-selective β-adrenergic receptor blocker. Sotalol is a potent antiarrhythmic agent that can be used for the research of pediatric arrhythmias. Sotalol blocks β-receptors, and potassium KCNH2 channels. Antiepileptic Agent[1][2][3][4].
References
[1] Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. DOI:10.1177/1060028018797110
[2] Marta Reyes-Corral, et al. Differential Free Intracellular Calcium Release by Class II Antiarrhythmics in Cancer Cell Lines. J Pharmacol Exp Ther. 2019 Apr;369(1):152-162. DOI:10.1124/jpet.118.254375
[3] Xiaomei Li, et al. Pediatric Dosing of Intravenous Sotalol Based on Body Surface Area in Patients with Arrhythmia. Pediatr Cardiol. 2017 Oct;38(7):1450-1455. DOI:10.1007/s00246-017-1683-9
[4] Kinga K Borowicz-Reutt, et al. Sotalol does not interfere with the antielectroshock action of selected second-generation antiepileptic drugs in mice.Pharmacol Rep. 2021 Apr;73(2):516-524. DOI:10.1007/s43440-020-00210-2
[2H6]-Sotalol Preparation Products And Raw materials
Raw materials
Preparation Products
[2H6]-Sotalol Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shanghai Beiwanta Biotechnology Co., Ltd. | 021-67187366 19901745723 | info@bwtlab.com | China | 9640 | 58 |
| SHANGHAI ZZBIO CO., LTD. | 15102117276 19921389125 | tech@zzbioco.com | China | 12064 | 58 |
| Supplier | Advantage |
|---|---|
| Shanghai Beiwanta Biotechnology Co., Ltd. | 58 |
| SHANGHAI ZZBIO CO., LTD. | 58 |
