N-(azide-PEG3)-N'-(Amine-C3-Amide-PEG4)-Cy5
- CAS No.
- 2107273-70-9
- Chemical Name:
- N-(azide-PEG3)-N'-(Amine-C3-Amide-PEG4)-Cy5
- Synonyms
- N-(azide-PEG3)-N'-(Amine-C3-PEG4)-Cy5;N-(azide-PEG3)-N'-(Amine-C3-Amide-PEG4)-Cy5;N-(azide-PEG3)-N'-(Amine-C3-Amide-PEG4)-Cy5
- CBNumber:
- CB38054761
- Molecular Formula:
- C47H70ClN7O8
- Molecular Weight:
- 896.57
- MDL Number:
- MFCD29764356
- MOL File:
- 2107273-70-9.mol
| Product description | Number | Pack Size | Price |
| N-(azide-PEG3)-N'-(Amine-C3-PEG4)-Cy5 98% | BP-23030 | 2mg | $360 |
N-(azide-PEG3)-N'-(Amine-C3-Amide-PEG4)-Cy5 Chemical Properties,Uses,Production
Description
N-(azide-PEG3)-N'-(Amine-C3-PEG4)-Cy5 is a PEG linker containing a cyanine dye with excitation/emmission maximum 649/667 nm as well as an azide group, which enables Click Chemistry. The hydophilic PEG spacer increases solubility in aqueous media.
Uses
N-(azide-PEG3)-N'-(Amine-C3-Amide-PEG4)-Cy5 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. N-(azide-PEG3)-N'-(Amine-C3-Amide-PEG4)-Cy5 is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
IC 50
PEGs
References
[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005
N-(azide-PEG3)-N'-(Amine-C3-Amide-PEG4)-Cy5 Preparation Products And Raw materials
Raw materials
Preparation Products
N-(azide-PEG3)-N'-(Amine-C3-Amide-PEG4)-Cy5 Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| TargetMol Chemicals Inc. | +1-781-999-5354; +17819995354 | marketing@targetmol.com | United States | 32435 | 58 |
| Jilin Chinese Academy of Sciences-yanshen Technology | +undefined18143011203 | info@chemextension.com | China | 42056 | 58 |
| Aladdin Scientific | tp@aladdinsci.com | United States | 52923 | 58 | |
| Jilin Chinese Academy of Sciences - Yanshen Technology Co., Ltd | 0431-0431-80514535 19917294565 | et@chemextension.com | China | 3935 | 55 |
| Zhengzhou Acme Chemical Co., Ltd. | 0371-037163312495,13303845143 13303845143 | 3001379618@qq.com | China | 10269 | 58 |
| Nanjing Shizhou Biology Technology Co.,Ltd | 025-85563444 18351873721 | purchase@synzest.com | China | 10434 | 58 |
| Beijing Jin Ming Biotechnology Co., Ltd. | 010-60605840 15801484223; | psaitong@jm-bio.com | China | 29757 | 58 |
| TargetMol Chemicals Inc. | 15002134094 | marketing@targetmol.cn | China | 29573 | 58 |
| Henan Mengtai Pharmaceutical Technology Co., Ltd | 176345344 7 17634854698 | 1959525201@qq.com | China | 10000 | 58 |
