ChemicalBook >> CAS DataBase List >>Glycine, N-[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]-, 1,1-dimethylethyl ester

Glycine, N-[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]-, 1,1-dimethylethyl ester

Glycine, N-[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]-, 1,1-dimethylethyl ester structure

CAS No.: 2093386-23-1

Chemical Name:: Glycine, N-[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]-, 1,1-dimethylethyl ester

Synonyms: Thalidomide-4-NH-C1-Boc;Thalidomide-NH-CH2-COO(t-Bu);tert-Butyl (2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)glycinate;Glycine, N-[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]-, 1,1-dimethylethyl ester

CBNumber:: CB38669738

Molecular Formula:: C19H21N3O6

Molecular Weight:: 387.39

MDL Number:

MOL File:: 2093386-23-1.mol

Last updated:2025-04-18 09:52:12

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Glycine, N-[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]-, 1,1-dimethylethyl ester Properties

Boiling point	608.3±55.0 °C(Predicted)
Density	1.397±0.06 g/cm3(Predicted)
pka	10.73±0.40(Predicted)

Glycine, N-[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]-, 1,1-dimethylethyl ester Chemical Properties,Uses,Production

Uses

Thalidomide-NH-CH2-COO (t-Bu) is a ligand for E3 ubiquitin ligase PROTAC BET Degrader-1 (HY-103633)[1].

IC 50

Cereblon

References

[1] Zhou B, et al. Discovery of a Small-Molecule Degrader of Bromodomain and Extra-Terminal (BET) Proteins with Picomolar Cellular Potencies and Capable of Achieving Tumor Regression. J Med Chem. 2018 Jan 25;61(2):462-481. DOI:10.1021/acs.jmedchem.6b01816

Glycine, N-[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]-, 1,1-dimethylethyl ester Preparation Products And Raw materials

Raw materials

Preparation Products

Glycine, N-[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]-, 1,1-dimethylethyl ester Suppliers

Global( 15)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
CR Corporation Limited	+8613062833949	fred.wen@crcorporation.cn	China	8645	58
Zhengzhou Lingzhiyue Technology Co., Ltd	+86-0371-55074660 +8613523716970	Lingzhiyue@aliyun.com	China	3145	58
Jilin Chinese Academy of Sciences-yanshen Technology	+undefined18143011203	info@chemextension.com	China	42056	58
Daicel Chiral Technologies (China)CO.,LTD	021-50460086-9 15921403865	han_yajun@dctc.daicel.com	China	6301	65
Amatek Scientific Co. Ltd.	0512-56316828	info@amateksci.com	China	28785	58
Zhengzhou Convergence Chemical Co. LTD	0371-0371-53736046 13393710386	2853979814@qq.com	China	9943	58
Lingyuan Bebiansen Biological Technology Co., Ltd	18642120371	2837458851@qq.com	China	7964	58
Xi'an Qiyue Biotechnology Co., Ltd.	400-400-6966-012-012 17778955912	2957605606@qq.com	China	2535	58
Yutong Pharmaceutical Technology (Suzhou) Co., Ltd.	0512-15851462628 15851462628	2680463261@qq.com	China	4996	58
Suzhou Haiben Pharmaceutical Co., Ltd	19353112242	1816280386@qq.com	China	8045	58

Supplier	Advantage
CR Corporation Limited	58
Zhengzhou Lingzhiyue Technology Co., Ltd	58
Jilin Chinese Academy of Sciences-yanshen Technology	58
Daicel Chiral Technologies (China)CO.,LTD	65
Amatek Scientific Co. Ltd.	58
Zhengzhou Convergence Chemical Co. LTD	58
Lingyuan Bebiansen Biological Technology Co., Ltd	58
Xi'an Qiyue Biotechnology Co., Ltd.	58
Yutong Pharmaceutical Technology (Suzhou) Co., Ltd.	58
Suzhou Haiben Pharmaceutical Co., Ltd	58

2093386-23-1(Glycine, N-[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]-, 1,1-dimethylethyl ester)Related Search:

tert-butyl (8-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)amino)octyl)carbamate Thalidomide-NH-PEG1-NH-Boc N-[2-[[2-(2,6-Dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]amino]ethyl]-carbamic Acid 1,1-Dimethylethyl Ester Carbamic acid, N-[2-[2-[2-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]amino]ethoxy]ethoxy]ethyl]-, 1,1-dimethylethyl ester 4-[(4-Aminobutyl)amino]-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione HCl

Thalidomide-NH-C3-NH-Boc N-[2-Aminoethyl] Pomalidomide Trifluoroacetic Acid Salt Carbamic acid, N-[6-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]amino]hexyl]-, 1,1-dimethylethyl ester

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Glycine, N-[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]-, 1,1-dimethylethyl ester Thalidomide-NH-CH2-COO(t-Bu) tert-Butyl (2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)glycinate Thalidomide-4-NH-C1-Boc 2093386-23-1