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(S)-3,4,5,6-tetrahydro-5-methyl-1-phenyl-1H-2,5-benzoxazocine hydrochloride

CAS No.
53648-31-0
Chemical Name:
(S)-3,4,5,6-tetrahydro-5-methyl-1-phenyl-1H-2,5-benzoxazocine hydrochloride
Synonyms
(S)-nefopam hydrochloride;(S)-3,4,5,6-tetrahydro-5-methyl-1-phenyl-1H-2,5-benzoxazocine hydrochloride
CBNumber:
CB3915570
Molecular Formula:
C17H20ClNO
Molecular Weight:
289.7998
MDL Number:
MOL File:
53648-31-0.mol
Last updated:2023-05-15 10:43:42

(S)-3,4,5,6-tetrahydro-5-methyl-1-phenyl-1H-2,5-benzoxazocine hydrochloride Properties

solubility DMSO (Sparingly), Water (Slightly)
form Solid
color Pale Red to Light Red
FDA UNII B7REK2R84C

(S)-3,4,5,6-tetrahydro-5-methyl-1-phenyl-1H-2,5-benzoxazocine hydrochloride Chemical Properties,Uses,Production

Uses

(+)-Nefopam inhibits the uptake of 5-hydroxytryptamine (5-HT), noradrenaline and dopamine in synaptosomal preparations from rat forebrain, hippocampus and striatum. A cyclized analog of orphenadrine and diphenhydramine; representative of a new class of centrally acting skeletal muscle relaxants, the benzoxazocines. Analgesic; antidepressant.

Definition

ChEBI: A hydrochloride obtained by reaction of (S)-nefopam with one equivalent of hydrochloric acid (the racemic salt is an analgesic drug).

(S)-3,4,5,6-tetrahydro-5-methyl-1-phenyl-1H-2,5-benzoxazocine hydrochloride Preparation Products And Raw materials

Raw materials

Preparation Products

(S)-nefopam hydrochloride (S)-3,4,5,6-tetrahydro-5-methyl-1-phenyl-1H-2,5-benzoxazocine hydrochloride 53648-31-0