Methanone, (3,4-dihydro-4-hydroxy-2(1H)-isoquinolinyl)[3-(3-hydroxy-3-methylbutyl)phenyl]-
- CAS No.
- 1377897-01-2
- Chemical Name:
- Methanone, (3,4-dihydro-4-hydroxy-2(1H)-isoquinolinyl)[3-(3-hydroxy-3-methylbutyl)phenyl]-
- Synonyms
- Methanone, (3,4-dihydro-4-hydroxy-2(1H)-isoquinolinyl)[3-(3-hydroxy-3-methylbutyl)phenyl]-
- CBNumber:
- CB39373621
- Molecular Formula:
- C21H25NO3
- Molecular Weight:
- 339.43
- MDL Number:
- MOL File:
- 1377897-01-2.mol
Methanone, (3,4-dihydro-4-hydroxy-2(1H)-isoquinolinyl)[3-(3-hydroxy-3-methylbutyl)phenyl]- Chemical Properties,Uses,Production
Description
ERD03 is an inhibitor of RNA-binding by EXOSC3, disrupting the EXOSC3-RNA interaction in a concentration-dependent manner.
Uses
ERD03 is a potent disruptor of the EXOSC3-RNA interaction, with a?Kd?of 17±7?μM?. ERD03 induces PCH1B-like phenotype in zebrafish embryo and can be used for neurological disorder?disease research[1].
References
[1] Liberty Fran?ois-Moutal, et al. A Chemical Biology Approach to Model Pontocerebellar Hypoplasia Type 1B (PCH1B). ACS Chem Biol. 2018 Oct 19;13(10):3000-3010. DOI:10.1021/acschembio.8b00745
Methanone, (3,4-dihydro-4-hydroxy-2(1H)-isoquinolinyl)[3-(3-hydroxy-3-methylbutyl)phenyl]- Preparation Products And Raw materials
Raw materials
Preparation Products
Methanone, (3,4-dihydro-4-hydroxy-2(1H)-isoquinolinyl)[3-(3-hydroxy-3-methylbutyl)phenyl]- Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| TargetMol Chemicals Inc. | +1-781-999-5354; | support@targetmol.com | United States | 39035 | 58 |
| Shanghai Yifei Biotechnology Co. , Ltd. | 021-65675885 18964387627 | customer_service@efebio.com | China | 11973 | 58 |
| TargetMol Chemicals Inc. | 15002134094 | marketing@targetmol.cn | China | 29257 | 58 |
| Supplier | Advantage |
|---|---|
| TargetMol Chemicals Inc. | 58 |
| Shanghai Yifei Biotechnology Co. , Ltd. | 58 |
| TargetMol Chemicals Inc. | 58 |





