NEUROPEPTIDE S (HUMAN)
- CAS No.
- 412938-67-1
- Chemical Name:
- NEUROPEPTIDE S (HUMAN)
- Synonyms
- NPS (HUMAN);SFRNGVGTGMKKTSFQRAKS;NEUROPEPTIDE S (HUMAN);Neuropeptide S, NPS, human;Neuropeptide S (huMan) NPS (huMan);SER-PHE-ARG-ASN-GLY-VAL-GLY-THR-GLY-MET-LYS-LYS-THR-SER-PHE-GLN-ARG-ALA-LYS-SER;H-SER-PHE-ARG-ASN-GLY-VAL-GLY-THR-GLY-MET-LYS-LYS-THR-SER-PHE-GLN-ARG-ALA-LYS-SER-OH;REF DUPL: H-Ser-Phe-Arg-Asn-Gly-Val-Gly-Ser-Gly-Ala-Lys-Lys-Thr-Ser-Phe-Arg-Arg-Ala-Lys-Gln-OH;L-Serine, L-seryl-L-phenylalanyl-L-arginyl-L-asparaginylglycyl-L-valylglycyl-L-threonylglycyl-L-methionyl-L-lysyl-L-lysyl-L-threonyl-L-seryl-L-phenylalanyl-L-glutaminyl-L-arginyl-L-alanyl-L-lysyl-
- CBNumber:
- CB4106928
- Molecular Formula:
- C93H155N31O28S
- Molecular Weight:
- 2187.48
- MDL Number:
- MFCD07368606
- MOL File:
- 412938-67-1.mol
NEUROPEPTIDE S (HUMAN) price More Price(5)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Alfa Aesar | J66262 | Neuropeptide S, human | 412938-67-1 | 0.2mg | $111 | 2021-12-16 | Buy |
| Alfa Aesar | J66262 | Neuropeptide S, human | 412938-67-1 | 0.5mg | $201 | 2021-12-16 | Buy |
| Alfa Aesar | J66262 | Neuropeptide S, human | 412938-67-1 | 1mg | $301 | 2021-12-16 | Buy |
| Usbiological | 302078 | Neuropeptide S, Human | 412938-67-1 | 100ug | $372 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | PEP0003707 | NEUROPEPTIDE S, HUMAN 95.00% | 412938-67-1 | 0.5MG | $676.83 | 2021-12-16 | Buy |
NEUROPEPTIDE S (HUMAN) Chemical Properties,Uses,Production
Biological Activity
Neuropeptide S human is a potent endogenous neuropeptide S receptor agonist (EC50=9.4 nM). It (TFA) increases motor activity and wakefulness in mice, and has potential for Alzheimer's disease (AD) research.
in vitro
Neuropeptide S human (4 pM to 1.7 nM; 48 hours) retains full agonist activity with an EC 50 of 6.7 ± 2.4 nM, the binding of [ 125I ] Y10-hNPS to CHO cells stably expressing hNPSR is saturable with high affinity (K d = 0.33 ± 0.12 nM). Neuropeptide S human (1 pM-3 μM; 48 hours) are used to compete with 0.15 nM [ 125I I] Y10-NPS, [ 125I I] Y10-NPS is displaceable by increasing concentrations of human NPS (IC 50 = 0.42 ± 0.12 nM).
in vivo
Neuropeptide S human (0.1 nM-1 nM; icv) causes a significant increase in locomotor activity, the total distance traveled, percentage of time moving, number of rearing events, and center entries are also significantly increased in mice .
| Animal Model: | Male C57Bl/6 mice |
| Dosage: | 0.1 nM, 1 nM |
| Administration: | Intracerebroventricular (icv) injection |
| Result: | Increased locomotor activity and promoted wakefulness. |
target
EC50: 9.4 nM (neuropeptide S receptor)
NEUROPEPTIDE S (HUMAN) Preparation Products And Raw materials
Raw materials
Preparation Products
NEUROPEPTIDE S (HUMAN) Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shenzhen Nexconn Pharmatechs Ltd | +86-755-89396905 +86-15013857715 | admin@nexconn.com | China | 10247 | 58 |
| Cellmano Biotech Limited | 0551-65326643 18156095617 | info@cellmano.com | China | 999 | 58 |
| Career Henan Chemica Co | +86-0371-86658258 15093356674; | laboratory@coreychem.com | China | 30255 | 58 |
| Chengdu Youngshe Chemical Co., Ltd. | +8618108235634 | Cecilia@youngshechem.com | China | 2345 | 58 |
| Nanjing TGpeptide | +86-13347807150 +86-13347807150 | support@tgpeptide.com | China | 3279 | 58 |
| Zhejiang Hangyu API Co., Ltd | +8617531972939 | anna@api-made.com | China | 2944 | 58 |
| Aladdin Scientific | +1-+1(833)-552-7181 | sales@aladdinsci.com | United States | 52927 | 58 |
| DONBOO AMINO ACID COMPANY | +8613063595538 | donboo@donboo.com | China | 9365 | 58 |
| GL Biochem (Shanghai) Ltd | 21-61263452 13641803416 | ymbetter@glbiochem.com | China | 9981 | 64 |
| Shanghai Hanhong Scientific Co.,Ltd. | 021-54306202 13764082696 | info@hanhongsci.com | China | 42982 | 64 |