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2-CHLORO-1,1,1-TRIFLUOROETHANE

2-CHLORO-1,1,1-TRIFLUOROETHANE Structure
2-CHLORO-1,1,1-TRIFLUOROETHANE structure
CAS No.
75-88-7
Chemical Name:
2-CHLORO-1,1,1-TRIFLUOROETHANE
Synonyms
r133a;HCFC-133A;CF3CH2Cl;HCFC-133;CFC 133a;F133a;1-CHLORO-2,2,2-TRIFLUOROETHANE;R 133a;cfc133a;FC-133A
CBNumber:
CB4108250
Molecular Formula:
C2H2ClF3
Molecular Weight:
118.49
MDL Number:
MFCD00039361
MOL File:
75-88-7.mol
Last updated:2023-05-06 17:15:45

2-CHLORO-1,1,1-TRIFLUOROETHANE Properties

Melting point -105°C
Boiling point 7°C
Density 1.389
refractive index 1.3090
form A liquid
CAS DataBase Reference 75-88-7(CAS DataBase Reference)
FDA UNII H86O899T9B
IARC 3 (Vol. 41, Sup 7, 71) 1999
EPA Substance Registry System HCFC-133a (75-88-7)

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS04
Signal word  Warning
Hazard statements  H280
Precautionary statements  P410+P403
Hazard Codes  Xi
Risk Statements  59
Safety Statements  9-23-59
RIDADR  1983
Hazard Note  Irritant
TSCA  T
HazardClass  2.2
Toxicity LCLo inhalation in guinea pig: 33000ppm/5H

2-CHLORO-1,1,1-TRIFLUOROETHANE Chemical Properties,Uses,Production

Chemical Properties

HCFC 133a is odorless with poor warning properties.

Uses

HCFC133a is a nonisolated intermediate in the production of halothane.

Definition

ChEBI: 2-Chloro-1,1,1-trifluoroethane is an organofluorine compound.

Synthesis Reference(s)

Journal of the American Chemical Society, 70, p. 758, 1948 DOI: 10.1021/ja01182a096

General Description

2-CHLORO-1,1,1-TRIFLUOROETHANE is a colorless, odorless gas. 2-CHLORO-1,1,1-TRIFLUOROETHANE is shipped as a liquid under its own vapor pressure. Contact with the liquid may cause frostbite to unprotected skin. 2-CHLORO-1,1,1-TRIFLUOROETHANE can asphyxiate by the displacement of air. Exposure of the container to fire or heat can cause 2-CHLORO-1,1,1-TRIFLUOROETHANE to rupture violently and rocket.

Reactivity Profile

2-CHLORO-1,1,1-TRIFLUOROETHANE is chemically inert in many situations, but can react violently with strong reducing agents such as the very active metals and the active metals. Undergoes oxidation with strong oxidizing agents and under extremes of temperature.

Health Hazard

Vapors may cause dizziness or asphyxiation without warning. Vapors from liquefied gas are initially heavier than air and spread along ground. Contact with gas or liquefied gas may cause burns, severe injury and/or frostbite. Fire may produce irritating, corrosive and/or toxic gases.

Fire Hazard

Some may burn but none ignite readily. Containers may explode when heated. Ruptured cylinders may rocket.

Safety Profile

A poison by inhalation. Experimental reproductive effects. Questionable carcinogen with experimental carcinogenic data. When heated to decomposition it emits toxic fumes of F-.

Carcinogenicity

HCFC 133a was evaluated in a carcinogenesis screening study using Wistar-derived rats. The rats were given daily intubations of 300mg HCFC of body weight in corn oil for 52 weeks and held for a total of 125 weeks. In the males, there was a reduction in body weight gain and testicular size, also there was an increase in Leydig cell tumors and arrest of spermatogenesis. In the females, there was an increased incidence of uterine carcinomas.

2-CHLORO-1,1,1-TRIFLUOROETHANE Preparation Products And Raw materials

Raw materials

2,2,2-Trifluoroethyl trifluoromethanesulfonate Trifluoromethanesulfonyl chloride 2,2,2-Trifluoroethanol N-nitrosobis(2,2,2-trifluoroethyl)amine 2,2,2-TRIFLUOROETHYLAMINE
BIS(2,2,2-TRIFLUOROETHYL)AMINE

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Preparation Products

1,1,1-Trichlorotrifluoroethane 2-CHLORO-1,1-DIFLUOROETHYLENE Halothane 1,1,1,2-Tetrafluoroethane

75-88-7(2-CHLORO-1,1,1-TRIFLUOROETHANE)Related Search:

2,3-DICHLOROOCTAFLUOROBUTANE Chloropentafluoroethane 1,1,2-TRICHLORO-3,3,3-TRIFLUOROPROPENE 2-CHLORO-1,1,1-TRIFLUOROETHANE HEXAFLUORO-2,2,3,3-TETRACHLOROBUTANE
Trifluoroacetyl chloride 1,1-Dichloro-2,2,2-trifluoroethane 1,1-Dibromo-1-chloro-2,2,2-trifluoroethane 1,2-DICHLOROHEXAFLUOROPROPANE 2-CHLORO-1,1,1-TRIFLUOROETHANE,1-CHLORO-2,2,2-TRIFLUOROETHANE
Halothane 1,1-DICHLOROTETRAFLUOROETHANE 2-Chloro-1,1,1,2-tetrafluoroethane 2,3-DICHLOROHEXAFLUORO-2-BUTENE 3-CHLOROHEPTAFLUORO-2-BUTENE
HEPTAFLUORO-2,3,3-TRICHLOROBUTANE 1,2-DIBROMO-1-CHLORO-1,2,2-TRIFLUOROETHANE,1,2-DIBROMO-1-CHLORO-1,2,2-TRIFLUOROETHANE 98+%,1,2-dibromo-2-chloro-1,1,2-trifluoroethan 1,2-DICHLORO-1,1-DIFLUOROETHANE

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Chlorotrifluoro ethane FC-133A 2-chloro-1,1,1-trifluoroethane(hcfc-133a) cfc133a chloro-1,1,1-trifluoroethane ethane,1-chloro-2,2,2-trifluoro- ethane,2-chloro-1,1,1-trifluoro- Forane133a 1,1,1-TRIFLUORO CHLOROETHANE 1，1，1-Trifluoro-2-chloroethane 2-CHLORO-1,1,1-TRIFLUOROETHANE 2,2,2-TRIFLUOROETHYL CHLORIDE 1-Chloro-2,2,2-trifluoroethane (FC-133a) TRIFLUOROETHYL CHLORIDE (Chloromethyl)trifluoromethane 1,1,1-Trifluor-2-chlorethan 1,1,1-Trifluorethylchlorid 1,1,1-Trifluoroethyl chloride 1,1,1-trifluoroethylchloride 1-Chlor-2,2,2-trifluorethan 1-Chloro-2,2,2-trifluoroethene 2,2,2-Trifluorochloroethane 2-chloro-1,1,1-trifluoro-ethan Freon 133a freon133a Genetron 133a genetron133a R 133a 1-Chloro-2,2,2-trifluoroethane(FC-133a)99% FLUOROCARBON133A Hydrochlorofluorocarbon-133a (HCFC-133a, R-133a) CYXIKYKBLDZZNW-UHFFFAOYSA-N 2-Chloro-1,1,1-trifluorethaneSolution(SecondSource),2000mg/L,1ml 2-Chloro-1,1,1-trifluorethaneSolution,2000mg/L,1ml 2-CHLORO-1,1,1-TRIFLUOROETHANE ISO 9001：2015 REACH HCFC-133A CF3CH2Cl CFC 133a F133a 1-CHLORO-2,2,2-TRIFLUOROETHANE r133a HCFC-133 2-chloro-1,1,1-trifluoroethane (HCFC 133a [75-88-7]) Norflurane EP Impurity FF Halothane EP Impurity E Xanthine Impurity 48 75-88-7 C2H2ClF3 HCFC refrigerants