ChemicalBook >> CAS DataBase List >>O-Desmethyl Metoprolol

O-Desmethyl Metoprolol

CAS No.
62572-94-5
Chemical Name:
O-Desmethyl Metoprolol
Synonyms
H 105/22;SL 80-008;SL 80-0088;Metoprolol-8;Betaxolol-001;O-demethylmetoprolo;Metoprolol-EP-Imp-H;Betaxolol Impurity 1;Betaxolol Impurity B;Metoprolol Impurity 8
CBNumber:
CB41176641
Molecular Formula:
C14H23NO3
Molecular Weight:
253.34
MDL Number:
MFCD01657298
MOL File:
62572-94-5.mol
Last updated:2023-06-08 09:02:50

O-Desmethyl Metoprolol Properties

Melting point 70-720C
Boiling point 424.6±40.0 °C(Predicted)
Density 1.085±0.06 g/cm3(Predicted)
storage temp. -20°C Freezer
solubility Chloroform (Slightly, Sonicated), Methanol (Slightly)
form Solid
pka 13.88±0.20(Predicted)
color White to Off-White
FDA UNII 9977TAV7FG

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H302
Precautionary statements  P264-P270-P301+P312-P330-P501
Toxicity LD50 intravenous in dog: 150mg/kg
NFPA 704
0
2 0

O-Desmethyl Metoprolol price More Price(11)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 21787 O-Desmethyl Metoprolol ≥95% 62572-94-5 1mg $49 2024-03-01 Buy
Cayman Chemical 21787 O-Desmethyl Metoprolol ≥95% 62572-94-5 5mg $216 2024-03-01 Buy
Cayman Chemical 21787 O-Desmethyl Metoprolol ≥95% 62572-94-5 10mg $380 2024-03-01 Buy
Usbiological 008628 O-Desmethyl Metoprolol 62572-94-5 5mg $425 2021-12-16 Buy
TRC D292073 O-DesmethylMetoprolol 62572-94-5 50mg $1155 2021-12-16 Buy
Product number Packaging Price Buy
21787 1mg $49 Buy
21787 5mg $216 Buy
21787 10mg $380 Buy
008628 5mg $425 Buy
D292073 50mg $1155 Buy

O-Desmethyl Metoprolol Chemical Properties,Uses,Production

Description

O-Desmethyl metoprolol is the major active metabolite of the β1-adrenergic receptor blocker metoprolol . It is formed by metabolism of metoprolol by the cytochrome P450 (CYP) isoform CYP2D6 in vivo.

Chemical Properties

Off-White Solid

Uses

O-Desmethyl Metoprolol (Metoprolol EP Impurity H) is a metabolite of Metoprolol.

O-Desmethyl Metoprolol Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 93)Suppliers
Supplier Tel Email Country ProdList Advantage
Hubei Jusheng Technology Co.,Ltd.
18871490254 linda@hubeijusheng.com CHINA 28180 58
Standardpharm Co. Ltd.
86-714-3992388 overseasales1@yongstandards.com United States 14336 58
BOC Sciences
+1-631-485-4226 inquiry@bocsci.com United States 19553 58
Career Henan Chemica Co
+86-0371-86658258 15093356674; laboratory@coreychem.com China 30255 58
ANHUI WITOP BIOTECH CO., LTD
+8615255079626 eric@witopchemical.com China 23556 58
CR Corporation Lomited
fred.wen@crcorporation.cn CHINA 12069 58
Hangzhou Huarong Pharm Co., Ltd.
571-86758373 +8613588754946 sales@huarongpharm.com CHINA 3149 58
sgtlifesciences pvt ltd
+8617013299288 dj@sgtlifesciences.com China 12382 58
Alfa Chemistry
+1-5166625404 Info@alfa-chemistry.com United States 21317 58
China National Standard Pharmaceutical Corporation Limited
+8615391658522 overseasales@yongstandards.com China 11927 58
(-4-[2-Hydroxy-3-(isopropylamino)propoxy]phenylethyl Alcohol (-O-Demethylmetoprolol 4-[2-Hydroxy-3-[(1-methylethyl)amino]propoxy]-benzeneethanol H 105/22 O-Desmethyl Metoprolol SL 80-008 O-demethylmetoprolo SL 80-0088 Metoprolol Tartrate EP IMpurity-H Metoprolol EP IMpurity H 1-(4-(2-hydroxyethyl)phenoxy) Metoprolol EP Impurity H (Betaxolol EP Impurity B) Metoprolol-EP-Imp-H Imp. H (EP):(2RS)-1-[4-(2-Hydroxyethyl)-phenoxy]-3-[(1-methylethyl)amino]propan-2-ol Metoprolol-8 Metoprolol impurity 6/Metoprolol EP Impurity H/O-Desmethyl Metoprolol/1-(4-(2-hydroxyethyl)phenoxy)-3-(isopropylamino)propan-2-ol Metoprolol Impurity 8 Betaxolol Impurity 1 1-(4-(2-hydroxyethyl)phenoxy)-3-(isopropylamino)propan-2-ol (2RS)-1-[4-(2-Hydroxyethyl)phenoxy]-3-[(1-methylethyl)amino]propan-2-ol Betaxolol-001 Betaxolol EP Impurity B Betaxolol Impurity 2(Betaxolol EP Impurity B) Metoprolol Impurity 8(Metoprolol EP Impurity H) (2RS)-1-[4-(2-Hydroxyethyl)phenoxy] Benzeneethanol, 4-[2-hydroxy-3-[(1-methylethyl)amino]propoxy]- 13/5000 Metoprolol tartrate impurity H Metoprolol EP Impurity H (O-Desmethyl Metoprolol) Betaxolol Impurity B Metoprolol Succinate EP Impurity H Betaxolol Hydrochloride EP Impurity B Metoprolol EP Impurity 8 Betaxolol EP Impurity B (Metoprolol EP Impurity H) 62572-94-5 Intermediates & Fine Chemicals Metabolites & Impurities Pharmaceuticals