Lexithromycin
- CAS No.
- 53066-26-5
- Chemical Name:
- Lexithromycin
- Synonyms
- Wy 48314;Lexithromycin;Erythromycin A-E-oxime;Azithromycin Impurity 4;Azithromycin Impurity 31;erythromycin A methoxime;Erythromycin A 9-Methoxime;Erythromycin, 9-(O-methyloxime);9-(Methoxyimino)-9-deoxoerythromycin;ErythroMycin A 9-MethoxiMe, Wy 48314
- CBNumber:
- CB41327717
- Molecular Formula:
- C38H70N2O13
- Molecular Weight:
- 762.97
- MDL Number:
- MOL File:
- 53066-26-5.mol
- MSDS File:
- SDS
| Melting point | >115°C (dec.) |
|---|---|
| Boiling point | 824.6±75.0 °C(Predicted) |
| Density | 1.26±0.1 g/cm3(Predicted) |
| storage temp. | Hygroscopic, -20°C Freezer, Under inert atmosphere |
| solubility | Chloroform (Slightly), DMSO (Slightly) |
| pka | 13.19±0.70(Predicted) |
| form | Solid |
| color | White to Off-White |
| Stability | Hygroscopic |
| FDA UNII | 7QKO29734U |
Lexithromycin price More Price(6)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Cayman Chemical | 22002 | Lexithromycin ≥98% | 53066-26-5 | 5mg | $171 | 2024-03-01 | Buy |
| Cayman Chemical | 22002 | Lexithromycin ≥98% | 53066-26-5 | 25mg | $760 | 2024-03-01 | Buy |
| ChemScene | CS-0026970 | Lexithromycin 98.80% | 53066-26-5 | 100mg | $1650 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | API0011780 | LEXITHROMYCIN 95.00% | 53066-26-5 | 5MG | $502.99 | 2021-12-16 | Buy |
| ChemScene | CS-0026970 | Lexithromycin 98.80% | 53066-26-5 | 25mg | $550 | 2021-12-16 | Buy |
Lexithromycin Chemical Properties,Uses,Production
Description
Lexithromycin is a semisynthetic antibiotic derived from erythromycin . Lexithromycin has improved absorption in vivo over erythromycin due to increased hydrophopicity and pH stability. As with other macrolides, lexithromycin prevents protein synthesis by binding the ribosome at the polypeptide exit tunnel. Formulations containing lexithromycin were tested in clinical trials as treatment for HIV but were discontinued.
Uses
Lexithromycin is a semi-synthetic erythromycin with improved pH stability and hydrophobicity. It is used in compositions and methods for treating viral infections.
Uses
Lexithromycin is an early semi-synthetic erythromycin, prepared by reaction of the 9-keto moiety to methyl oxime. The structural change improves the pH stability profile and hydrophobicity of lexithromycin for better in vivo absorption. This same rationale was used to greater effect with roxithromycin and, as a result, lexithromycin was quickly superseded and has not been not extensively studied. Like all tetracyclines, lexithromycin shows broad spectrum antibacterial and antiprotozoan activity and acts by binding to the 30S and 50S ribosomal sub-units, blocking protein synthesis.
Lexithromycin Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Standardpharm Co. Ltd. | 86-714-3992388 | overseasales1@yongstandards.com | United States | 14336 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 19892 | 58 |
| ANHUI WITOP BIOTECH CO., LTD | +8615255079626 | eric@witopchemical.com | China | 23556 | 58 |
| BOC Sciences | +16314854226 | inquiry@bocsci.com | United States | 19743 | 58 |
| Henan Alfa Chemical Co., Ltd | +8618339805032 | alfa4@alfachem.cn | China | 12755 | 58 |
| InvivoChem | +1-708-310-1919 +1-13798911105 | sales@invivochem.cn | United States | 6393 | 58 |
| China National Standard Pharmaceutical Corporation Limited | +8615391658522 | overseasales@yongstandards.com | China | 11927 | 58 |
| S.Z. PhyStandard Bio-Tech. Co., Ltd. | 0755-4000505016 13380397412 | 3001272453@qq.com | China | 4974 | 50 |
| ChemStrong Scientific Co.,Ltd | 0755-0755-66853366 13670046396 | sales@chem-strong.com | China | 17982 | 56 |
| Shanghai Kewel Chemical Co., Ltd. | 021-64609169 18901607656 | greensnown@163.com | China | 9911 | 50 |
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