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Thalidomide-4-O-C10-COOH

Thalidomide-4-O-C10-COOH structure

CAS No.: 2379870-45-6

Chemical Name:: Thalidomide-4-O-C10-COOH

Synonyms: Thalidomide-4-O-C10-COOH;11-[[2-(2,6-Dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]oxy]undecanoic Acid;Undecanoic acid, 11-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]oxy]-

CBNumber:: CB413888950

Molecular Formula:: C24H30N2O7

Molecular Weight:: 458.51

MDL Number:

MOL File:: 2379870-45-6.mol

Last updated:2025-04-18 09:52:17

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Thalidomide-4-O-C10-COOH Properties

Boiling point	704.561±55.00 °C(Press: 760.00 Torr)(predicted)
Density	1.290±0.06 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted)
pka	4.779±0.10(predicted)
form	Solid
color	White to off-white

Thalidomide-4-O-C10-COOH Chemical Properties,Uses,Production

Uses

Thalidomide-4-O-C10-COOH is a E3 ligase ligand-linker conjugate that can be used in the synthesis of PROTACs.

IC 50

Cereblon

References

[1] Powell CE, et al. Selective degradation-inducing probes for studying cereblon (CRBN) biology. RSC Med Chem. 2021 Jul 6;12(8):1381-1390. DOI:10.1039/d0md00382d

Thalidomide-4-O-C10-COOH Preparation Products And Raw materials

Raw materials

Preparation Products

Thalidomide-4-O-C10-COOH Suppliers

Global( 2)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Daicel Chiral Technologies (China)CO.,LTD	021-50460086-9 15921403865	han_yajun@dctc.daicel.com	China	4801	65
Guangzhou Baide Biotechnology Co., Ltd.	18925065404		CHINA	0	58

Supplier	Advantage
Daicel Chiral Technologies (China)CO.,LTD	65
Guangzhou Baide Biotechnology Co., Ltd.	58

Thalidomide-4-O-C10-COOH 11-[[2-(2,6-Dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]oxy]undecanoic Acid Undecanoic acid, 11-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]oxy]- 2379870-45-6