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BIOTIN-X-NHS, WATER-SOLUBLE, CLEAVABLE

CAS No.
122266-55-1
Chemical Name:
BIOTIN-X-NHS, WATER-SOLUBLE, CLEAVABLE
Synonyms
NHS-SS-BIOTIN;Sulfo-SS-Biotin;Biotin-SS-NHS ester;NHS-SS-biotin,Biotin-SS-NHS;SULFOBIOTIN-X-NHS, CLEAVABLE;BIOTIN-X-NHS, WATER-SOLUBLE, CLEAVABLE;SULFOSUCCINIMIDYL-2-(BIOTINAMIDO)ETHYL-1,3-DITHIOPROPIONATE;SULFOSUCCINIMIDYL 2-(BIOTINAMIDE)ETHYL-1,3-DITHIOPROPIONATE;SULFOSUCCINIMIDYL 3-[[2-(BIOTINAMIDO)ETHYL] DITHIO]PROPIONATE;Propanoic acid, 3-[[2-[[5-[(3aS,4S,6aR)-hexahydro-2-oxo-1H-thieno[3,4-d]imidazol-4-yl]-1-oxopentyl]amino]ethyl]dithio]-, 2,5-dioxo-1-pyrrolidinyl ester
CBNumber:
CB4216304
Molecular Formula:
C19H28N4O6S3
Molecular Weight:
504.64
MDL Number:
MFCD28505564
MOL File:
Mol file
Last updated:2024-03-21 17:31:59

BIOTIN-X-NHS, WATER-SOLUBLE, CLEAVABLE Properties

storage temp. 0-6°C
solubility ≥28.79 mg/mL in DMSO; insoluble in H2O; insoluble in EtOH

BIOTIN-X-NHS, WATER-SOLUBLE, CLEAVABLE price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
ApexBio Technology A8006 NHS-SS-Biotin 122266-55-1 100mg $100 2021-12-16 Buy
BroadPharm BP-22636 NHS-SS-biotin 90% 122266-55-1 100mg $290 2021-12-16 Buy
BroadPharm BP-22636 NHS-SS-biotin 90% 122266-55-1 1g $1470 2021-12-16 Buy
Product number Packaging Price Buy
A8006 100mg $100 Buy
BP-22636 100mg $290 Buy
BP-22636 1g $1470 Buy

BIOTIN-X-NHS, WATER-SOLUBLE, CLEAVABLE Chemical Properties,Uses,Production

Description

NHS-SS-biotin is a cleavable reagent which can efficiently introduce a biotin moiety to amine-containing biomolecules. This biotin compound is membrane-permeable and useful for intracellular labeling. The disulfide bond in this linker can be cleaved using reducing agents such as DTT, BME and TCEP to remove the biotin label.

Uses

NHS SS Biotin is a amine reactive biotinylation reagent that labels antibodies and other proteins and molecules that contain primary amines. NHS SS Biotin reacts efficiently with pirmary amino groups in alkaline buffers to form stable amide bonds. The disulfide bond in the spacer arm of NHS SS Biotin is also cleavable using reducing agents such as TCEP and DTT.

Biological Activity

nhs-ss-biotin (succinimidyl-2-(biotinamido)-ethyl-1,3-dithiopropionate) is a long-chain cleavable amine-reactive biotinylation reagent that has a spacer arm of 24.3 a in length due to the existence of a cross-bridge within its chemical structure. the long spacer arm creates an increased length between a covalently modified molecule and the bicyclic biotin rings that greatly enhances the ability of the molecule to bind to avidin or streptavidin probes. the nhs ester group of nhs-ss-biotin reacts with the amine groups of proteins and other molecule forming an amide bond and releasing of sulfo-nhs. nhs-ss-biotin is a water-insoluble molecule that requires the dissolution of organic solvents prior to be added to aqueous reactions.bioconjugate techniques , 2nd ed. by greg t.hermanson (pierce biotechnology, thermo fisher scientific, rockford, il). academic press (an imprint of elsevier): london, amsterdam, burlington, san diego . 2008. isbn 978-0-12-370501-3.

BIOTIN-X-NHS, WATER-SOLUBLE, CLEAVABLE Preparation Products And Raw materials

Raw materials

Preparation Products

BIOTIN-X-NHS, WATER-SOLUBLE, CLEAVABLE Suppliers

Global( 82)Suppliers
Supplier Tel Email Country ProdList Advantage
TargetMol Chemicals Inc.
+1-781-999-5354 +1-00000000000 marketing@targetmol.com United States 19892 58
Zhejiang J&C Biological Technology Co.,Limited
+1-2135480471 +1-2135480471 sales@sarms4muscle.com China 10523 58
Hangzhou Huarong Pharm Co., Ltd.
571-86758373 +8613588754946 sales@huarongpharm.com CHINA 3149 58
Hangzhou MolCore BioPharmatech Co.,Ltd.
+86-057181025280; +8617767106207 sales@molcore.com China 49739 58
Hebei Miaoyin Technology Co.,Ltd
+86-17367732028 +86-17367732028 kathy@hbyinsheng.com China 3582 58
Jilin Chinese Academy of Sciences-yanshen Technology
+undefined18143011203 info@chemextension.com China 42057 58
Xian confluore Biological Technology Co., Ltd.
+86-15680926068 +86-15680926068 1924344760@confluore.cn China 2893 58
Aladdin Scientific
+1-833-552-7181 sales@aladdinsci.com United States 52927 58
Jiangsu shring Biopharma Co., Ltd. +8613372282299 sales@shringchem.com China 3545 58
3B Pharmachem (Wuhan) International Co.,Ltd. 821-50328103-801 18930552037 3bsc@sina.com China 15848 69

View Lastest Price from BIOTIN-X-NHS, WATER-SOLUBLE, CLEAVABLE manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Biotin-SS-NHS ester pictures 2024-03-21 Biotin-SS-NHS ester
122266-55-1
US $0.00 / mg 50mg >95.00% 50mg Xian confluore Biological Technology Co., Ltd.
  • Biotin-SS-NHS ester pictures
  • Biotin-SS-NHS ester
    122266-55-1
  • US $0.00 / mg
  • >95.00%
  • Xian confluore Biological Technology Co., Ltd.

BIOTIN-X-NHS, WATER-SOLUBLE, CLEAVABLE Spectrum

SULFOBIOTIN-X-NHS, CLEAVABLE SULFOSUCCINIMIDYL 2-(BIOTINAMIDE)ETHYL-1,3-DITHIOPROPIONATE SULFOSUCCINIMIDYL-2-(BIOTINAMIDO)ETHYL-1,3-DITHIOPROPIONATE SULFOSUCCINIMIDYL 3-[[2-(BIOTINAMIDO)ETHYL] DITHIO]PROPIONATE NHS-SS-BIOTIN BIOTIN-X-NHS, WATER-SOLUBLE, CLEAVABLE Sulfo-SS-Biotin NHS-SS-biotin,Biotin-SS-NHS Biotin-SS-NHS ester Propanoic acid, 3-[[2-[[5-[(3aS,4S,6aR)-hexahydro-2-oxo-1H-thieno[3,4-d]imidazol-4-yl]-1-oxopentyl]amino]ethyl]dithio]-, 2,5-dioxo-1-pyrrolidinyl ester 122266-55-1 C19H28N4O6S3 Biotinylation Reagents