(2β,5α,12β,19α,20S)-6,7-Didehydro-3α,20-epoxy-2-hydroxyaspidospermidine-3-carboxylic acid methyl ester

(2β,5α,12β,19α,20S)-6,7-Didehydro-3α,20-epoxy-2-hydroxyaspidospermidine-3-carboxylic acid methyl ester structure

CAS No.: 11034-66-5

Chemical Name:: (2β,5α,12β,19α,20S)-6,7-Didehydro-3α,20-epoxy-2-hydroxyaspidospermidine-3-carboxylic acid methyl ester

Synonyms: Vincoline;20-Epimelobaline;20-epi-Melobaline;(2β,5α,12β,19α,20S)-6,7-Didehydro-3α,20-epoxy-2-hydroxyaspidospermidine-3-carboxylic acid methyl ester;Aspidospermidine-3-carboxylic acid, 6,7-didehydro-3,20-epoxy-2-hydroxy-, methyl ester, (2β,3α,5α,12R,19α,20S)-

CBNumber:: CB42181972

Molecular Formula:: C21H24N2O4

Molecular Weight:: 368.43

MDL Number:

MOL File:: 11034-66-5.mol

Last updated:2022-12-21 16:56:50

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(2β,5α,12β,19α,20S)-6,7-Didehydro-3α,20-epoxy-2-hydroxyaspidospermidine-3-carboxylic acid methyl ester Properties

Melting point	228-232 °C
Boiling point	556.0±50.0 °C(Predicted)
Density	1.42±0.1 g/cm3(Predicted)
pka	11.14±0.60(Predicted)
FDA UNII	QLD37A79WK

(2β,5α,12β,19α,20S)-6,7-Didehydro-3α,20-epoxy-2-hydroxyaspidospermidine-3-carboxylic acid methyl ester Chemical Properties,Uses,Production

Description

One of the Vinca alkaloids, vincoline has been assigned the structure shown above which is based primarily upon spectroscopic data.

References

Aynilian et al.,f. Pharm. Sci., 63536 (1974)

(2β,5α,12β,19α,20S)-6,7-Didehydro-3α,20-epoxy-2-hydroxyaspidospermidine-3-carboxylic acid methyl ester Preparation Products And Raw materials

Raw materials

Preparation Products

(2β,5α,12β,19α,20S)-6,7-Didehydro-3α,20-epoxy-2-hydroxyaspidospermidine-3-carboxylic acid methyl ester 20-Epimelobaline 20-epi-Melobaline Vincoline Aspidospermidine-3-carboxylic acid, 6,7-didehydro-3,20-epoxy-2-hydroxy-, methyl ester, (2β,3α,5α,12R,19α,20S)- 11034-66-5