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ChemicalBook >> CAS DataBase List >>1-[2-fluoro-6-(trifluoromethyl)benzyl]-5-iodo-6-methylpyrimidine-2,4(1H,3H)-dione

1-[2-fluoro-6-(trifluoromethyl)benzyl]-5-iodo-6-methylpyrimidine-2,4(1H,3H)-dione

1-[2-fluoro-6-(trifluoromethyl)benzyl]-5-iodo-6-methylpyrimidine-2,4(1H,3H)-dione Structure
1-[2-fluoro-6-(trifluoromethyl)benzyl]-5-iodo-6-methylpyrimidine-2,4(1H,3H)-dione structure
CAS No.
1150560-54-5
Chemical Name:
1-[2-fluoro-6-(trifluoromethyl)benzyl]-5-iodo-6-methylpyrimidine-2,4(1H,3H)-dione
Synonyms
EOS-60322;Elagolix Impurity 5;elagolix intermediate 5;1-(2-fluoro-6-(trifluoromethyl)benzyl)-5-iodo-6-methylpyrimi...;1-(2-Fluoro-6-trifluoromethyl-benzyl)-5-iodo-6-methyl-1H-pyrimidine-2,4-dione;1-[2-fluoro-6-(trifluoromethyl)benzyl]-5-iodo-6-methylpyrimidine-2,4(1H,3H)-dione;1-[[2-fluoro-6-(trifluoromethyl)phenyl]methyl]-5-iodo-6-methylpyrimidine-2,4-dione;1-[[2-fluoro-6-(trifluoromethyl)phenyl]methyl]-5-iodo-6-methyl-2,4(1H,3H)-Pyrimidine dione;2,4(1H,3H)-Pyrimidinedione, 1-[[2-fluoro-6-(trifluoromethyl)phenyl]methyl]-5-iodo-6-methyl-;1-[[2-Fluoro-6-(trifluoromethyl)phenyl]methyl]-5-iodo-6-methyl- 2-2,4(1H,3H)- pyrimidinedione
CBNumber:
CB42473697
Molecular Formula:
C13H9F4IN2O2
Molecular Weight:
428.12
MDL Number:
MFCD19441362
MOL File:
1150560-54-5.mol
Last updated:2023-04-23 13:52:06
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1-[2-fluoro-6-(trifluoromethyl)benzyl]-5-iodo-6-methylpyrimidine-2,4(1H,3H)-dione Properties

Melting point >190oC (dec.)
Density 1.88±0.1 g/cm3(Predicted)
storage temp. -20°C Freezer, Under inert atmosphere
solubility Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly, Heated)
pka 8.04±0.40(Predicted)
form Solid
color White to Off-White
LogP 2

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P280-P301+P312-P302+P352-P305+P351+P338

1-[2-fluoro-6-(trifluoromethyl)benzyl]-5-iodo-6-methylpyrimidine-2,4(1H,3H)-dione price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TRC F599485 1-{[2-Fluoro-6-(trifluoromethyl)phenyl]methyl}-5-iodo-6-methyl-1,2,3,4-tetrahydropyrimidine-2,4-dione 1150560-54-5 50mg $45 2021-12-16 Buy
American Custom Chemicals Corporation HCH0621037 1-([2-FLUORO-6-(TRIFLUOROMETHYL)PHENYL]METHYL)-5-IODO-6-METHYL-1,2,3,4-TETRAHYDROPYRIMIDINE-2,4-DIONE 95.00% 1150560-54-5 5MG $453.81 2021-12-16 Buy
AK Scientific 8741BB 1-(2-Fluoro-6-(trifluoromethyl)benzyl)-5-iodo-6-methylpyrimidine-2,4(1H,3H)-dione 1150560-54-5 5g $633 2021-12-16 Buy
Crysdot CD11346258 1-(2-Fluoro-6-(trifluoromethyl)benzyl)-5-iodo-6-methylpyrimidine-2,4(1H,3H)-dione 95+% 1150560-54-5 10g $680 2021-12-16 Buy
Chemenu CM105026 1-{[2-fluoro-6-(trifluoromethyl)phenyl]methyl}-5-iodo-6-methyl-1,2,3,4-tetrahydropyrimidine-2,4-dione 95+% 1150560-54-5 500g $920 2021-12-16 Buy
Product number Packaging Price Buy
F599485 50mg $45 Buy
HCH0621037 5MG $453.81 Buy
8741BB 5g $633 Buy
CD11346258 10g $680 Buy
CM105026 500g $920 Buy

1-[2-fluoro-6-(trifluoromethyl)benzyl]-5-iodo-6-methylpyrimidine-2,4(1H,3H)-dione Chemical Properties,Uses,Production

Physical Form

Solid

Uses

1-{[2-fluoro-6-(trifluoromethyl)phenyl]methyl}-5-iodo-6-methyl-1,2,3,4-tetrahydropyrimidine-2,4-dione is an intermediate in the synthesis of Elagolix, a gonadotropin-releasing hormone antagonist (GnRH) used in the treatment of endometriosis.

Uses

1-[2-fluoro-6-(trifluoromethyl)benzyl]-5-iodo-6-methylpyrimidine-2,4(1H,3H)-dione is a useful research chemical.

1-[2-fluoro-6-(trifluoromethyl)benzyl]-5-iodo-6-methylpyrimidine-2,4(1H,3H)-dione synthesis

830346-47-9
1150560-54-5
Synthesis of 1-[2-fluoro-6-(trifluoromethyl)benzyl]-5-iodo-6-methylpyrimidine-2,4(1H,3H)-dione from Benzeneacetic acid, 4-fluoro-.alpha.-(1-methylethyl)-, (.alpha.S)-

1-[2-fluoro-6-(trifluoromethyl)benzyl]-5-iodo-6-methylpyrimidine-2,4(1H,3H)-dione Preparation Products And Raw materials

Raw materials

Benzaldehyde, 2-fluoro-6-(trifluoromethyl)-, oxime 3-Fluorobenzotrifluoride 2-FLUORO-6-(TRIFLUOROMETHYL)BENZALDEHYDE Benzeneacetic acid, 4-fluoro-.alpha.-(1-methylethyl)-, (.alpha.S)- 2-FLUORO-6-(TRIFLUOROMETHYL)BENZYLAMINE

Preparation Products

5-(2-Fluoro-3-methoxyphenyl)-1-[[2-fluoro-6-(trifluoromethyl)phenyl]methyl]-6-methyl-2,4(1H,3H)-pyrimidinedione

1-[2-fluoro-6-(trifluoromethyl)benzyl]-5-iodo-6-methylpyrimidine-2,4(1H,3H)-dione Suppliers

Global( 156)Suppliers
Supplier Tel Email Country ProdList Advantage
Capot Chemical Co.,Ltd. 		571-85586718 +8613336195806 sales@capotchem.com China 29797 60
Beijing Cooperate Pharmaceutical Co.,Ltd 		010-60279497 sales01@cooperate-pharm.com CHINA 1811 55
ATK CHEMICAL COMPANY LIMITED 		+undefined-21-51877795 ivan@atkchemical.com China 32480 60
career henan chemical co 		+86-0371-86658258 sales@coreychem.com China 29914 58
Zhejiang ZETian Fine Chemicals Co. LTD 		18957127338 stella@zetchem.com China 2141 58
Shandong ruiyue Biological Technology Co.，Ltd. 		008615066100122（Lily wechat） 513075341@qq.com CHINA 52 58
Chongqing Chemdad Co., Ltd 		+86-023-61398051 +8613650506873 sales@chemdad.com China 39916 58
Alchem Pharmtech,Inc. 		8485655694 sales@alchempharmtech.com United States 63711 58
Shanghai Jinghao Pharmaceutical Co.,Ltd 		+86-21-68900963 sales@jinghaopharma.com CHINA 153 58
Shanghai Yingrui Biopharma Co.,Ltd 		21-33585366 export01@shyrchem.com CHINA 1320 58
Supplier Advantage
Capot Chemical Co.,Ltd. 		60
Beijing Cooperate Pharmaceutical Co.,Ltd 		55
ATK CHEMICAL COMPANY LIMITED 		60
career henan chemical co 		58
Zhejiang ZETian Fine Chemicals Co. LTD 		58
Shandong ruiyue Biological Technology Co.，Ltd. 		58
Chongqing Chemdad Co., Ltd 		58
Alchem Pharmtech,Inc. 		58
Shanghai Jinghao Pharmaceutical Co.,Ltd 		58
Shanghai Yingrui Biopharma Co.,Ltd 		58

View Lastest Price from 1-[2-fluoro-6-(trifluoromethyl)benzyl]-5-iodo-6-methylpyrimidine-2,4(1H,3H)-dione manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
1-[2-fluoro-6-(trifluoromethyl)benzyl]-5-iodo-6-methylpyrimidine-2,4(1H,3H)-dione pictures 2021-07-09 1-[2-fluoro-6-(trifluoromethyl)benzyl]-5-iodo-6-methylpyrimidine-2,4(1H,3H)-dione
1150560-54-5
 1KG 99% + 500 Ton/Tons per Month Hebei Xibaijie Biotechnology Co., Ltd.
1-[[2-fluoro-6-(trifluoromethyl)phenyl]methyl]-5-iodo-6-methylpyrimidine-2,4-dione pictures 2021-07-02 1-[[2-fluoro-6-(trifluoromethyl)phenyl]methyl]-5-iodo-6-methylpyrimidine-2,4-dione
1150560-54-5
 US $15.00-10.00 / KG 1KG 99%+ HPLC Monthly supply of 1 ton Zhuozhou Wenxi import and Export Co., Ltd
1-[2-fluoro-6-(trifluoromethyl)benzyl]-5-iodo-6-methylpyrimidine-2,4(1H,3H)-dione pictures 2019-07-06 1-[2-fluoro-6-(trifluoromethyl)benzyl]-5-iodo-6-methylpyrimidine-2,4(1H,3H)-dione
1150560-54-5
 US $10000.00 / KG 1KG 99% 10kg Career Henan Chemical Co

1-[2-fluoro-6-(trifluoromethyl)benzyl]-5-iodo-6-methylpyrimidine-2,4(1H,3H)-dione Spectrum

1-[2-fluoro-6-(trifluoromethyl)benzyl]-5-iodo-6-methylpyrimidine-2,4(1H,3H)-dione(1150560-54-5)1HNMR

1150560-54-5(1-[2-fluoro-6-(trifluoromethyl)benzyl]-5-iodo-6-methylpyrimidine-2,4(1H,3H)-dione)Related Search:

INTERMEDIATES 1-(2-fluoro-6-(trifluoroMethyl)benzyl)-6-Methyl-5-(piperazin-1-yl)pyriMidine-2,4(1H,3H)-dione Elagolix Sodium elagolix (R)-2-(Boc-aMino)-2-phenylethyl 4-Methylbenzenesulfonate
1-[(1R)-2-hydroxy-1-phenylethyl]pyrrolidin-2-one Carbamic acid, N-[(1R)-2-[5-(2-fluoro-3-methoxyphenyl)-3-[[2-fluoro-6-(trifluoromethyl)phenyl]methyl]-3,6-dihydro-4-methyl-2,6-dioxo-1(2H)-pyrimidinyl]-1-phenylethyl]-, 1,1-dimethylethyl ester 5-(2-Fluoro-3-methoxyphenyl)-1-[[2-fluoro-6-(trifluoromethyl)phenyl]methyl]-6-methyl-2,4(1H,3H)-pyrimidinedione 3-[(2R)-2-Amino-2-phenylethyl]-5-(2-fluoro-3-methoxyphenyl)-1-[[2-fluoro-6-(trifluoromethyl)phenyl]methyl]-6-methyl-2,4(1H,3H)-pyrimidinedione 5-Bromo-1-(2-fluoro-6-trifluoromethyl-benzyl)-6-methyl-1H-pyrimidine-2,4-dione
Carbamic acid, N-[(1R)-2-[5-bromo-3-[[2-fluoro-6-(trifluoromethyl)phenyl]methyl]-3,6-dihydro-4-methyl-2,6-dioxo-1(2H)-pyrimidinyl]-1-phenylethyl]-, 1,1-dimethylethyl ester T-BUTYL 4-BROMOBUTYRATE 2,2'-difluoro-3,3'-dimethoxy-1,1'-biphenyl Elagolix Sodium impurity4 (R)-1,2-Diamino-1-phenylethane
1-(2-FLUORO-6-(TRIFLOROMETHYL)BENZYL)UREA 3-Bromo-2-fluoroanisole Carbamic acid, N-[(1R)-2-[5-(2-fluoro-3-hydroxyphenyl)-3-[[2-fluoro-6-(trifluoromethyl)phenyl]methyl]-3,6-dihydro-4-methyl-2,6-dioxo-1(2H)-pyrimidinyl]-1-phenylethyl]-, 1,1-dimethylethyl ester

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1-[[2-fluoro-6-(trifluoromethyl)phenyl]methyl]-5-iodo-6-methyl-2,4(1H,3H)-Pyrimidine dione 1-[2-fluoro-6-(trifluoromethyl)benzyl]-5-iodo-6-methylpyrimidine-2,4(1H,3H)-dione elagolix intermediate 5 1-{[2-fluoro-6-(trifluoromethyl)phenyl]methyl}-5-iodo-6-methyl-1,2,3,4-tetrahydropyrimidine-2,4-dione EOS-60322 1-[[2-Fluoro-6-(trifluoromethyl)phenyl]methyl]-5-iodo-6-methyl-2,4(1H,3H)-pyrimidinedione1-[[2-Fluoro-6-(trifluoromethyl)phenyl]methyl]-5-iodo-6-methyl-2,4(1H,3H)-pyrimidinedione 1-[[2-fluoro-6-(trifluoromethyl)phenyl]methyl]-5-iodo-6-methylpyrimidine-2,4-dione 1-[[2-Fluoro-6-(trifluoromethyl)phenyl]methyl]-5-iodo-6-methyl- 2-2,4(1H,3H)- pyrimidinedione 1-(2-Fluoro-6-trifluoromethyl-benzyl)-5-iodo-6-methyl-1H-pyrimidine-2,4-dione Elagolix Impurity 5 2,4(1H,3H)-Pyrimidinedione, 1-[[2-fluoro-6-(trifluoromethyl)phenyl]methyl]-5-iodo-6-methyl- 1-(2-fluoro-6-(trifluoromethyl)benzyl)-5-iodo-6-methylpyrimi... 1150560-54-5 C13H9F4IN2O2