ChemicalBook >> CAS DataBase List >>PHACLOFEN
PHACLOFEN
- CAS No.
- 114012-12-3
- Chemical Name:
- PHACLOFEN
- Synonyms
- PHACLOFEN;PHACLOFEN GABA(B) RECEPTOR ANTA;3-AMINO-2-(4-CHLOROPHENYL)PROPYLPHOSPHONIC ACID;3-amino-2-(4-chlorophenyl)*propanephosphonic acid;(RS)-3-AMINO-2-(4-CHLOROPHENYL)PROPYLPHOSPHONIC ACID;Phosphonic acid, (3-amino-2-(4-chlorophenyl)propyl)-;Phosphonic acid, P-[3-amino-2-(4-chlorophenyl)propyl]-;Phaclofen,(RS)-3-Amino-2-(4-chlorophenyl)propylphosphonicaci
- CBNumber:
- CB4272748
- Molecular Formula:
- C9H13ClNO3P
- Molecular Weight:
- 249.63
- MDL Number:
- MFCD00069328
- MOL File:
- 114012-12-3.mol
Last updated:2023-07-12 16:57:10
| Melting point | 249-252 °C |
|---|---|
| Boiling point | 467.1±55.0 °C(Predicted) |
| Density | 1.432±0.06 g/cm3(Predicted) |
| storage temp. | Store at RT |
| solubility | 0.1 M HCl: 13.3 mg/mL |
| form | solid |
| pka | 1.87±0.10(Predicted) |
| color | white |
| EWG's Food Scores | 1 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H315-H319-H335 |
| Precautionary statements | P261-P264-P271-P280-P302+P352-P305+P351+P338 |
| Hazard Codes | Xi |
| Risk Statements | 36/37/38 |
| Safety Statements | 26-36 |
| WGK Germany | 3 |
PHACLOFEN price More Price(10)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | P118 | Phaclofen solid | 114012-12-3 | 5mg | $132.6 | 2024-03-01 | Buy |
| Sigma-Aldrich | P118 | Phaclofen solid | 114012-12-3 | 25mg | $833 | 2024-03-01 | Buy |
| Sigma-Aldrich | P118 | Phaclofen solid | 114012-12-3 | 100mg | $2520 | 2024-03-01 | Buy |
| Usbiological | 256229 | Phaclofen | 114012-12-3 | 10mg | $389 | 2021-12-16 | Buy |
| ApexBio Technology | B6215 | Phaclofen | 114012-12-3 | 10mg | $218 | 2021-12-16 | Buy |
PHACLOFEN Chemical Properties,Uses,Production
Uses
Phaclofen is a selective GABAB?receptor antagonist.
General Description
Phaclofen is a phosphonic acid derivative of baclofen.
Biological Activity
Selective GABA B antagonist. Phosphono analog of GABA B agonist baclofen ((RS)-4-Amino-3-(4-chlorophenyl)butanoic acid ).
Biochem/physiol Actions
Phaclofen plays a vital role in identifying the physiological importance of central and peripheral bicuculline-insensitive receptors with which GABA and (?) baclofen interact. Phaclofen acts as a GABAB receptor antagonist. Phaclofen has an ability to reversibly block the late, bicuculline resistant, K+ dependent inhibitory postsynaptic potential (IPSP) logged in projection cells of the cat and rat dorsal lateral geniculate nucleus and in rat hippocampal CA1 pyramidal neurons.
PHACLOFEN Preparation Products And Raw materials
Raw materials
Preparation Products
PHACLOFEN Suppliers
Global( 52)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hangzhou FandaChem Co.,Ltd. | 008657128800458; +8615858145714 | fandachem@gmail.com | China | 9341 | 55 |
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 19892 | 58 |
| Aladdin Scientific | +1-833-552-7181 | sales@aladdinsci.com | United States | 52927 | 58 |
| 3B Pharmachem (Wuhan) International Co.,Ltd. | 821-50328103-801 18930552037 | 3bsc@sina.com | China | 15848 | 69 |
| Syntechem Co.,Ltd | info@syntechem.com | China | 12990 | 57 | |
| Beijing Yisiyan Technology Research Center | 010-56645598 13366904824 | bjkaida@163.com | China | 1652 | 59 |
| Sigma-Aldrich | 021-61415566 800-8193336 | orderCN@merckgroup.com | China | 51471 | 80 |
| EMMX Biotechnology LLC | 888-539-0666 | info@emmx.com | United States | 8449 | 60 |
| Shanghai EFE Biological Technology Co., Ltd. | 021-65675885 18964387627 | info@efebio.com | China | 9709 | 58 |
| BOC Sciences | -- | info@bocsci.com | USA | 0 | 65 |
114012-12-3(PHACLOFEN)Related Search:
3-AMINO-2-(4-CHLOROPHENYL)PROPYLPHOSPHONIC ACID
PHACLOFEN
(RS)-3-AMINO-2-(4-CHLOROPHENYL)PROPYLPHOSPHONIC ACID
3-amino-2-(4-chlorophenyl)*propanephosphonic acid
PHACLOFEN GABA(B) RECEPTOR ANTA
Phosphonic acid, (3-amino-2-(4-chlorophenyl)propyl)-
Phosphonic acid, P-[3-amino-2-(4-chlorophenyl)propyl]-
Phaclofen,(RS)-3-Amino-2-(4-chlorophenyl)propylphosphonicaci
114012-12-3
C9H13CINO3P
C9H13ClNO3P
GABA/Glycine receptor