Acetyl-Coenzyme A Assay Kit

CAS No.
Chemical Name:
Acetyl-Coenzyme A Assay Kit
Synonyms
Acetyl-Coenzyme A Assay Kit
CBNumber:
CB42893785
Molecular Formula:
Molecular Weight:
0
MDL Number:
MOL File:
Mol file
Last updated:2022-08-15 17:37:32

Acetyl-Coenzyme A Assay Kit Properties

Flash point 87 °C
storage temp. -20°C

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P264-P271-P280-P302+P352-P305+P351+P338

Acetyl-Coenzyme A Assay Kit price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich MAK039 Acetyl-Coenzyme A Assay Kit sufficient for 100?fluorometric?tests 1kit $578 2024-03-01 Buy
Product number Packaging Price Buy
MAK039 1kit $578 Buy

Acetyl-Coenzyme A Assay Kit Chemical Properties,Uses,Production

Uses

Acetyl-Coenzyme A Assay Kit has been used to quantify the level of acetyl-CoA in astrocytes exposed to recombinant HIV protein Tat and Cocaine. It has also been used to study the mitochondrial metabolism by evaluating the levels of acetyl-CoA using hypoxia induced stress in primary human ventricular cardiomyocytes.

General Description

Acetyl-CoA is an essential cofactor and carrier of acyl groups in enzymatic acetyl transfer reactions. It is formed either by the oxidative decarboxylation of pyruvate in mitochondria, by the oxidation of long-chain fatty acids, or by the oxidative degradation of certain amino acids. Acetyl-CoA is the starting compound for the citric acid cycle (Kreb′s cycle). It is also a key precursor in lipid biosynthesis, and the source of all fatty acid carbons. Acetyl-CoA positively regulates the activity of pyruvate carboxylase. It is a precursor of the neurotransmitter acetylcholine. Histone acetylases (HAT) use Acetyl-CoA as the donor for the acetyl group used in the post-translational acetylation reactions of histone and non-histone proteins.

Acetyl-Coenzyme A acts as an indicator of fat, sugar, and protein levels and shows up on the nutritional status. Thus, starvation greatly reduces the level of acetyl-CoA, which stimulates the process of autophagy. In lowered glucose condition, acetyl-CoA participates in the production of ATP. Increased acetyl-CoA levels are observed in prostate cancer due to elevated fatty acid utilization and thus provides an additional energy source for the tumor cell growth. Nutrition deprivation, changes the levels of certain metabolites, including acetyl-CoA, which stimulates epigenetic modifications that would affect the central nervous system.

Acetyl-Coenzyme A Assay Kit Preparation Products And Raw materials

Raw materials

Preparation Products

Acetyl-Coenzyme A Assay Kit Suppliers

Global( 3)Suppliers
Supplier Tel Email Country ProdList Advantage
Beijing Boorsen Biotechnology Co., Ltd 400-901-9800 18611424007 cis@bioss.com.cn China 9518 58
Sigma-Aldrich 021-61415566 800-8193336 orderCN@merckgroup.com China 51471 80
Acetyl-Coenzyme A Assay Kit