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Angiogenesis Inhibitor

CAS No.
186611-44-9
Chemical Name:
Angiogenesis Inhibitor
Synonyms
Angiogenesis Inhibitor;Angiogenesis Inhibitor - CAS 186611-44-9 - Calbiochem;2H-Indol-2-one, 1,3-dihydro-3-(1H-imidazol-5-ylmethylene)-
CBNumber:
CB43136740
Molecular Formula:
C12H9N3O
Molecular Weight:
211.22
MDL Number:
MOL File:
186611-44-9.mol
Last updated:2023-05-04 17:34:35

Angiogenesis Inhibitor Properties

Melting point 228-230 °C(Solv: ethanol (64-17-5))
Boiling point 572.7±50.0 °C(Predicted)
Density 1.404±0.06 g/cm3(Predicted)
storage temp. +2C to +8C
form Yellow solid
pka 11.70±0.20(Predicted)
NCI Dictionary of Cancer Terms angiogenesis inhibitor

Angiogenesis Inhibitor price More Price(3)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 175580 Angiogenesis Inhibitor - CAS 186611-44-9 - Calbiochem 186611-44-9 10mg $172 2024-03-01 Buy
TRC A637973 AngiogenesisInhibitor 186611-44-9 25mg $335 2021-12-16 Buy
TRC A637973 AngiogenesisInhibitor 186611-44-9 10mg $170 2021-12-16 Buy
Product number Packaging Price Buy
175580 10mg $172 Buy
A637973 25mg $335 Buy
A637973 10mg $170 Buy

Angiogenesis Inhibitor Chemical Properties,Uses,Production

Uses

Angiogenesis Inhibitor is a cell-permeable indolinone. Anti-angiogenic activity.

Definition

ChEBI: 3-(1H-imidazol-5-ylmethylidene)-1H-indol-2-one is a member of indoles.

General Description

A cell-permeable indolinone compound that displays anti-angiogenesis properties (30% inhibition of control at 10 μM in an in vitro rat aortic ring model). The potency has been reported to be comparable to that of SU5416 (Cat. No. 676487; 22% inhibition of control at 10 μM). Acts as a moderate ATP-competitive inhibitor of hEGF-R tyrosine kinase activity (54% inhibition at 10 μM).

Biochem/physiol Actions

Cell permeable: yes

Angiogenesis Inhibitor Preparation Products And Raw materials

Raw materials

Preparation Products

Angiogenesis Inhibitor Suppliers

Global( 6)Suppliers
Supplier Tel Email Country ProdList Advantage
Aladdin Scientific
+1-+1(833)-552-7181 sales@aladdinsci.com United States 52927 58
Sigma-Aldrich 021-61415566 800-8193336 orderCN@merckgroup.com China 51471 80
Energy Chemical 021-58432009 400-005-6266 marketing1@energy-chemical.com China 44843 58
Shaoguan Qicheng Biotechnology Co., Ltd 18122215013 780229652@qq.com China 1107 58
Angiogenesis Inhibitor Angiogenesis Inhibitor - CAS 186611-44-9 - Calbiochem 2H-Indol-2-one, 1,3-dihydro-3-(1H-imidazol-5-ylmethylene)- 186611-44-9