4-(1H-IMIDAZOL-4-YLMETHYL)PIPERIDINE DIHYDROBROMIDE
- CAS No.
- 164391-47-3
- Chemical Name:
- 4-(1H-IMIDAZOL-4-YLMETHYL)PIPERIDINE DIHYDROBROMIDE
- Synonyms
- Zinc00005777;Immepip hydrobromide;IMMEPIP DIHYDROBROMIDE;4-(1H-Imidazol-5-ylmethyl)piperidine hydrobromide;4-(1H-IMIDAZOL-4-YLMETHYL)PIPERIDINE DIHYDROBROMIDE;Piperidine,4-(1H-imidazol-4-ylmethyl)-,dihydrobromide
- CBNumber:
- CB4459345
- Molecular Formula:
- C9H17Br2N3
- Molecular Weight:
- 327.06
- MDL Number:
- MFCD06407876
- MOL File:
- 164391-47-3.mol
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H302 | |||||||||
| Precautionary statements | P264-P270-P301+P312-P501 | |||||||||
| Hazard Codes | Xn | |||||||||
| Risk Statements | 22 | |||||||||
| WGK Germany | 3 | |||||||||
| NFPA 704 |
|
4-(1H-IMIDAZOL-4-YLMETHYL)PIPERIDINE DIHYDROBROMIDE price More Price(17)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | I4034 | Immepip dihydrobromide ≥97% (HPLC), powder | 164391-47-3 | 10mg | $204 | 2024-03-01 | Buy |
| Sigma-Aldrich | I4034 | Immepip dihydrobromide ≥97% (HPLC), powder | 164391-47-3 | 50mg | $646 | 2024-03-01 | Buy |
| Cayman Chemical | 29518 | Immepip (hydrobromide) | 164391-47-3 | 1mg | $33 | 2024-03-01 | Buy |
| Cayman Chemical | 29518 | Immepip (hydrobromide) | 164391-47-3 | 5mg | $120 | 2024-03-01 | Buy |
| Cayman Chemical | 29518 | Immepip (hydrobromide) | 164391-47-3 | 10mg | $160 | 2024-03-01 | Buy |
4-(1H-IMIDAZOL-4-YLMETHYL)PIPERIDINE DIHYDROBROMIDE Chemical Properties,Uses,Production
Description
Immepip is a histamine H3 receptor agonist (KI = 0.4 nM in SK-N-MC cell membranes expressing the human receptor). It is selective for histamine H3 over H1 and H2 receptors in CHO cell membranes expressing the guinea pig and human receptors, respectively (Kis = >16 μM for both) but also agonizes H4 receptors (KI = 9 nM in SK-N-MC cell membranes expressing the human receptor). Immepip (5 mg/kg, s.c.) decreases hypothalamic histamine release in anesthetized rats. It decreases flinching in the formalin test in rats when administered at doses of 5 and 30 mg/kg and inhibits formalin-induced paw edema at 30 mg/kg.
Chemical Properties
Crystalline Solid
Uses
A selective nonchiral histamine H3 agonist.
Biological Activity
Potent histamine H 3 receptor agonist. Also binds to H 4 receptors (K i values are 0.4 and 9 nM at human recombinant H 3 and H 4 receptors respectively). Equipotent to or slightly more active than (R)- α -methylhistamine at H 3 receptors.
storage
Desiccate at RT
4-(1H-IMIDAZOL-4-YLMETHYL)PIPERIDINE DIHYDROBROMIDE Preparation Products And Raw materials
Raw materials
Preparation Products
4-(1H-IMIDAZOL-4-YLMETHYL)PIPERIDINE DIHYDROBROMIDE Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 19892 | 58 |
| J & K SCIENTIFIC LTD. | 010-82848833 400-666-7788 | jkinfo@jkchemical.com | China | 96815 | 76 |
| 3B Pharmachem (Wuhan) International Co.,Ltd. | 821-50328103-801 18930552037 | 3bsc@sina.com | China | 15848 | 69 |
| Chemsky（shanghai）International Co.,Ltd. | 021-50135380 | shchemsky@sina.com | China | 32344 | 50 |
| SynAsst Chemical. | 021-60343070 | China | 12742 | 55 | |
| Suzhou yacoo science co.,Ltd | 0512-87182056 18013166090 | lingling.qi@yacoo.com.cn | China | 7300 | 60 |
| EMMX Biotechnology LLC | 888-539-0666 | info@emmx.com | United States | 8449 | 60 |
| Shanghai EFE Biological Technology Co., Ltd. | 021-65675885 18964387627 | info@efebio.com | China | 9709 | 58 |
| Amatek Scientific Co. Ltd. | 0512-56316828 | info@amateksci.com | China | 28822 | 58 |
| Aikon International Limited | 025-58859352 18068836627 | sales01@aikonchem.com | China | 15085 | 58 |