Anti-L1CAM antibody, Mouse monoclonal

CAS No.
Chemical Name:
Anti-L1CAM antibody, Mouse monoclonal
Synonyms
Anti-L1CAM antibody, Mouse monoclonal
CBNumber:
CB44669386
Molecular Formula:
Molecular Weight:
0
MDL Number:
MOL File:
Mol file
Last updated:2023-04-23 13:52:06

Anti-L1CAM antibody, Mouse monoclonal Properties

storage temp. -20°C
form buffered aqueous solution

Anti-L1CAM antibody, Mouse monoclonal price More Price(2)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich L4543 Anti-L1CAM antibody, Mouse monoclonal clone UJ127.11, purified from hybridoma cell culture 25μL $184 2024-03-01 Buy
Sigma-Aldrich L4543 Anti-L1CAM antibody, Mouse monoclonal clone UJ127.11, purified from hybridoma cell culture 200μL $660 2024-03-01 Buy
Product number Packaging Price Buy
L4543 25μL $184 Buy
L4543 200μL $660 Buy

Anti-L1CAM antibody, Mouse monoclonal Chemical Properties,Uses,Production

Uses

Anti-L1CAM antibody has been used in immunohistochemistry.

General Description

The gene L1CAM (L1 cell adhesion molecule) encodes a member of the immunoglobulin supergene family. The encoded protein contains a cytoplasmic intracellular domain, one single-pass transmembrane region and an extracellular domain containing six immunoglobulin- (Ig) and five fibronectin (Fn) III-like motifs. The gene is mapped to human chromosome Xq28. It contains 29 exons that encode a protein of 1257 amino acids containing a 19 amino acid signal peptide and a functional L1 protein of 1238 amino acids. It is mainly expressed in the nervous system.

Biochem/physiol Actions

The gene L1CAM (L1 cell adhesion molecule) encodes a glycoprotein that functions in axon growth during development and axon bundling. It interacts with Schwann cells and axons, and mediates neuronal cell migration, and neuronal cell survival. Overexpression of this protein is associated with tumor progression. It has been found to mediate therapeutic resistance in ovarian and pancreatic cancer cells.

Anti-L1CAM antibody, Mouse monoclonal Preparation Products And Raw materials

Raw materials

Preparation Products

Anti-L1CAM antibody, Mouse monoclonal Suppliers

Global( 1)Suppliers
Supplier Tel Email Country ProdList Advantage
Sigma-Aldrich 021-61415566 800-8193336 orderCN@merckgroup.com China 51471 80
Supplier Advantage
Sigma-Aldrich 80
Anti-L1CAM antibody, Mouse monoclonal