Anti-L1CAM antibody, Mouse monoclonal
- CAS No.
- Chemical Name:
- Anti-L1CAM antibody, Mouse monoclonal
- Synonyms
- Anti-L1CAM antibody, Mouse monoclonal
- CBNumber:
- CB44669386
- Molecular Formula:
- Molecular Weight:
- 0
- MDL Number:
- MOL File:
- Mol file
Anti-L1CAM antibody, Mouse monoclonal price More Price(2)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich | L4543 | Anti-L1CAM antibody, Mouse monoclonal clone UJ127.11, purified from hybridoma cell culture | 25μL | $184 | 2024-03-01 | Buy | |
Sigma-Aldrich | L4543 | Anti-L1CAM antibody, Mouse monoclonal clone UJ127.11, purified from hybridoma cell culture | 200μL | $660 | 2024-03-01 | Buy |
Anti-L1CAM antibody, Mouse monoclonal Chemical Properties,Uses,Production
Uses
Anti-L1CAM antibody has been used in immunohistochemistry.
General Description
The gene L1CAM (L1 cell adhesion molecule) encodes a member of the immunoglobulin supergene family. The encoded protein contains a cytoplasmic intracellular domain, one single-pass transmembrane region and an extracellular domain containing six immunoglobulin- (Ig) and five fibronectin (Fn) III-like motifs. The gene is mapped to human chromosome Xq28. It contains 29 exons that encode a protein of 1257 amino acids containing a 19 amino acid signal peptide and a functional L1 protein of 1238 amino acids. It is mainly expressed in the nervous system.
Biochem/physiol Actions
The gene L1CAM (L1 cell adhesion molecule) encodes a glycoprotein that functions in axon growth during development and axon bundling. It interacts with Schwann cells and axons, and mediates neuronal cell migration, and neuronal cell survival. Overexpression of this protein is associated with tumor progression. It has been found to mediate therapeutic resistance in ovarian and pancreatic cancer cells.
Anti-L1CAM antibody, Mouse monoclonal Preparation Products And Raw materials
Raw materials
Preparation Products
Anti-L1CAM antibody, Mouse monoclonal Suppliers
Supplier | Tel | Country | ProdList | Advantage | |
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Sigma-Aldrich | 021-61415566 800-8193336 | orderCN@merckgroup.com | China | 51471 | 80 |
Supplier | Advantage |
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Sigma-Aldrich | 80 |