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APETx2

APETx2 structure

CAS No.: 713544-47-9

Chemical Name:: APETx2

Synonyms: APETx2;Cys6-Cys30;Cys20-Cys38);APETx2 USP/EP/BP;APETx2, ASIC3 channel blocker;APETx2, Anthopleura elegantissima, Recombinant, E. coli;H-Gly-Thr-Ala-Cys-Ser-Cys-Gly-Asn-Ser-Lys-Gly-Ile-Tyr-Trp-Phe-Tyr-Arg-Pro-Ser-Cys-Pro-Thr-Asp-Arg-Gly-Tyr-Thr-Gly-Ser-Cys-Arg-Tyr-Phe-Leu-Gly-Thr-Cys-Cys-Thr-Pro-Ala-Asp-OH(Disulfide bridge：Cys4-Cys37;2-[2-[[1-[2-[[52-[2-[[2-[(2-aminoacetyl)amino]-3-hydroxybutanoyl]amino]propanoylamino]-34-(4-aminobutyl)-40-(2-amino-2-oxoethyl)-19,69-dibenzyl-28-butan-2-yl-13,75,96-tris(3-carbamimidamidopropyl)-99-(carboxymethyl)-2~{a},60,87-tris(1-hydroxyethyl)-4,37,49,81-tetrakis(hydroxymethyl)-16,25,72,90-tetrakis[(4-hydroxyphenyl)methyl]-22-(1~{H}-indol-3-ylmethyl)-66-(2-methylpropyl)-1~{a},3,4~{a},6,10~{a},12,15,17~{a},18,21,24,27,30,33,36,39,42,45,48,51,59,62,65,68,71,74,77,80,83,86,89,92,95,98-tetratriacontaoxo-12~{a},13~{a},19~{a},20~{a},54,55-hexathia-~{a},2,3~{a},5,9~{a},11,14,16~{a},17,20,23,26,2

CBNumber:: CB44673963

Molecular Formula:: C196H280N54O61S6

Molecular Weight:: 0

MDL Number:

MOL File:: Mol file

Last updated:2025-06-18 16:39:34

Product description	Number	Pack Size	Price
APETx2	4804	100U	$363
APETx2	254652	100ug	$644
APETx2	B5720	100ug	$528

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APETx2 Properties

storage temp.	Store at -20°C
solubility	aqueous buffer: soluble
form	Powder
Water Solubility	Soluble to 5 mg/ml in water
Sequence	Gly-Thr-Ala-Cys-Ser-Cys-Gly-Asn-Ser-Lys-Gly-Ile-Tyr-Trp-Phe-Tyr-Arg-Pro-Ser-Cys-Pro-Thr-Asp-Arg-Gly-Tyr-Thr-Gly-Ser-Cys-Arg-Tyr-Phe-Leu-Gly-Thr-Cys-Cys-Thr-Pro-Ala-Asp (Disulfide bridge:Cys4-Cys37;Cys6-Cys30;Cys20-Cys38)
UNSPSC Code	12352200

APETx2 price More Price(3)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Tocris	4804	APETx2	713544-47-9	100U	$363	2021-12-16	Buy
Usbiological	254652	APETx2	713544-47-9	100ug	$644	2021-12-16	Buy
ApexBio Technology	B5720	APETx2	713544-47-9	100ug	$528	2021-12-16	Buy

Product number	Packaging	Price	Buy
4804	100U	$363	Buy
254652	100ug	$644	Buy
B5720	100ug	$528	Buy

APETx2 Chemical Properties,Uses,Production

Uses

APETx2 is a highly pure, synthetic and biologically active peptide toxin.

Biological Activity

APETx2, a sea anemone peptide from Anthopleura elegantissima, is a selective and reversible acid-sensing ion channel inhibitor of ASIC3 (acid-sensing ion channel) with IC50 of 63 nM. It acts outside the ASIC3 channel. APETx2 reverses acid-induced inflammatory pain.

in vitro

APETx2 (it or im application, 0.022 to 2.2 μM) resulted in a potent and complete reversal of established mechanical hypersensitivity in the complete Freund's adjuvant (CFA) inflammatory pain model.

storage

Store at -20°C

APETx2 Preparation Products And Raw materials

Raw materials

Preparation Products

APETx2 Suppliers

Global( 55)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Shenzhen Nexconn Pharmatechs Ltd	+86-755-89396905 +86-15013857715	admin@nexconn.com	China	10405	58
BOC Sciences	+1-631-485-4226	inquiry@bocsci.com	United States	19552	58
Career Henan Chemica Co	+86-0371-86658258 +8613203830695	laboratory@coreychem.com	China	30229	58
Dideu Industries Group Limited	+86-29-89586680 +86-15129568250	1026@dideu.com	China	20284	58
Zhejiang J&C Biological Technology Co.,Limited	+1-2135480471	sales@sarms4muscle.com	China	10473	58
Hangzhou Huarong Pharm Co., Ltd.	571-86758373 +8613588754946	sales@huarongpharm.com	CHINA	3148	58
HANGZHOU LEAP CHEM CO., LTD.	+86-571-87711850	market18@leapchem.com	China	43339	58
Aladdin Scientific		tp@aladdinsci.com	United States	57505	58
Changsha MOL Changes Biotechnology Co., Ltd.	+8619375158599	info@molchanges.com	China	5218	58
Creative Peptides		info@creative-peptides.com	United States	6083	56

Supplier	Advantage
Shenzhen Nexconn Pharmatechs Ltd	58
BOC Sciences	58
Career Henan Chemica Co	58
Dideu Industries Group Limited	58
Zhejiang J&C Biological Technology Co.,Limited	58
Hangzhou Huarong Pharm Co., Ltd.	58
HANGZHOU LEAP CHEM CO., LTD.	58
Aladdin Scientific	58
Changsha MOL Changes Biotechnology Co., Ltd.	58
Creative Peptides	56

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1of3

APETx2 2-[2-[[1-[2-[[52-[2-[[2-[(2-aminoacetyl)amino]-3-hydroxybutanoyl]amino]propanoylamino]-34-(4-aminobutyl)-40-(2-amino-2-oxoethyl)-19,69-dibenzyl-28-butan-2-yl-13,75,96-tris(3-carbamimidamidopropyl)-99-(carboxymethyl)-2~{a},60,87-tris(1-hydroxyethyl)-4,37,49,81-tetrakis(hydroxymethyl)-16,25,72,90-tetrakis[(4-hydroxyphenyl)methyl]-22-(1~{H}-indol-3-ylmethyl)-66-(2-methylpropyl)-1~{a},3,4~{a},6,10~{a},12,15,17~{a},18,21,24,27,30,33,36,39,42,45,48,51,59,62,65,68,71,74,77,80,83,86,89,92,95,98-tetratriacontaoxo-12~{a},13~{a},19~{a},20~{a},54,55-hexathia-~{a},2,3~{a},5,9~{a},11,14,16~{a},17,20,23,26,2 APETx2 USP/EP/BP Cys20-Cys38) Cys6-Cys30 H-Gly-Thr-Ala-Cys-Ser-Cys-Gly-Asn-Ser-Lys-Gly-Ile-Tyr-Trp-Phe-Tyr-Arg-Pro-Ser-Cys-Pro-Thr-Asp-Arg-Gly-Tyr-Thr-Gly-Ser-Cys-Arg-Tyr-Phe-Leu-Gly-Thr-Cys-Cys-Thr-Pro-Ala-Asp-OH(Disulfide bridge：Cys4-Cys37 APETx2, ASIC3 channel blocker APETx2, Anthopleura elegantissima, Recombinant, E. coli 713544-47-9 C196H280N54O61S6