L-CYSTEINESULFINIC ACID MONOHYDRATE
- CAS No.
- 207121-48-0
- Chemical Name:
- L-CYSTEINESULFINIC ACID MONOHYDRATE
- Synonyms
- 3-sulfino-l-alanine;Sulfino-L-alanine hydrate;L-Cysteinesulfinic Acid (hydrate);(2R)-2-aMino-3-sulfinopropanoic acid;L-Cysteinesulfinic acid Monohydrate 99%;(1R)-1-amino-2-mercaptoethanesulfinic acid hydrate;L Cysteinesulfinic acid monohydrate,LCysteinesulfinic acid monohydrate,Metabotropic glutamate receptors,Inhibitor,L-Cysteinesulfinic acid,inhibit,mGluR
- CBNumber:
- CB4503615
- Molecular Formula:
- HO2SCH2CH(NH2)CO2HH2O
- Molecular Weight:
- 171.17
- MDL Number:
- MFCD00150732
- MOL File:
- 207121-48-0.mol
- MSDS File:
- SDS
SAFETY
Risk and Safety Statements
Symbol(GHS) | GHS07 |
---|---|
Signal word | Warning |
Hazard statements | H315-H319-H335 |
Precautionary statements | P261-P264-P271-P280-P302+P352-P305+P351+P338 |
Hazard Codes | Xi |
Risk Statements | 36/37/38 |
Safety Statements | 26-36 |
WGK Germany | 3 |
HS Code | 2930901300 |
L-CYSTEINESULFINIC ACID MONOHYDRATE price More Price(28)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich | 270881 | L-Cysteinesulfinic acid monohydrate 99% | 207121-48-0 | 1g | $796 | 2024-03-01 | Buy |
Sigma-Aldrich | 270881 | L-Cysteinesulfinic acid monohydrate 99% | 207121-48-0 | 250mg | $201 | 2023-06-20 | Buy |
Cayman Chemical | 29597 | L-Cysteinesulfinic Acid (hydrate) | 207121-48-0 | 50mg | $61 | 2024-03-01 | Buy |
Cayman Chemical | 29597 | L-Cysteinesulfinic Acid (hydrate) | 207121-48-0 | 100mg | $111 | 2024-03-01 | Buy |
Sigma-Aldrich | C4418 | L-Cysteinesulfinic acid monohydrate | 207121-48-0 | 100mg | $134 | 2024-03-01 | Buy |
L-CYSTEINESULFINIC ACID MONOHYDRATE Chemical Properties,Uses,Production
Description
L-Cysteinesulfinic acid is an excitatory amino acid and agonist of metabotropic glutamate receptors (mGluRs). It increases intracellular inositol phosphate levels in CHO cells expressing mGluR1, mGluR5, or mGluR8 (EC50s = 120, 30, and 110 μM, respectively) and inhibits forskolin-induced cAMP production in CHO cells expressing mGluR2 or mGluR6 and hamster kidney cells expressing mGluR4 (EC50s = 100, 100, and 2,000 μM, respectively). It selectively binds to mGluR1α (Ki = 3,510 nM) over adrenergic, dopamine, histamine, muscarinic, nicotinic, or serotonin receptors (Kis = >10,000 nM for all). L-Cysteinesulfinic acid (1 mM) decreases mean arterial blood pressure and heart rate in rats when microinjected into the nucleus tractus solitarius (NTS). L-Cysteinesulfinic acid can be formed via oxidation of L-cysteine by reactive oxygen species (ROS), and conversion of cysteine to L-cysteinesulfinic acid in cysteine-containing peptide probes has been used to measure oxidative stress.
Chemical Properties
Off-White Solid
Uses
L-Cysteinesulfinic acid monohydrate has been used in the fluorescence measurement of cysteine oxidation.
Uses
An amino acid derivative with neuropathological interest; Putative excitatory amino acid neurotransmitter.
Biochem/physiol Actions
Cysteinesulfinic acid (CSA), also called 3-sulfinoalanine is synthesized by the conversion of sulfur to sulfinic acid in cysteine by the enzyme cysteine dioxygenase (CDO). CSA is a putative excitatory amino acid (EAA) with neurotransmitter functionality. It also regulates cardiovascular functions.
L-CYSTEINESULFINIC ACID MONOHYDRATE Preparation Products And Raw materials
Raw materials
Preparation Products
L-CYSTEINESULFINIC ACID MONOHYDRATE Suppliers
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
Zhengzhou Alfa Chemical Co.,Ltd | +8618530059196 | sale04@alfachem.cn | China | 13349 | 58 |
Hong Kong Tiansheng New Material Trading Co., Ltd | +8617320695765 | zxx@hktiansheng.com | China | 981 | 58 |
TargetMol Chemicals Inc. | +1-781-999-5354 | support@targetmol.com | United States | 19973 | 58 |
J & K SCIENTIFIC LTD. | 010-82848833 400-666-7788 | jkinfo@jkchemical.com | China | 96815 | 76 |
Energy Chemical | 021-021-58432009 400-005-6266 | sales8178@energy-chemical.com | China | 44700 | 61 |
Chemsky(shanghai)International Co.,Ltd. | 021-50135380 | shchemsky@sina.com | China | 32344 | 50 |
Syntechem Co.,Ltd | info@syntechem.com | China | 12990 | 57 | |
Sigma-Aldrich | 021-61415566 800-8193336 | orderCN@merckgroup.com | China | 51471 | 80 |
Shanghai EFE Biological Technology Co., Ltd. | 021-65675885 18964387627 | info@efebio.com | China | 9707 | 58 |
Shanghai YuanYe Biotechnology Co., Ltd. | 021-61312847; 18021002903 | 3008007409@qq.com | China | 27314 | 60 |
View Lastest Price from L-CYSTEINESULFINIC ACID MONOHYDRATE manufacturers
Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
---|---|---|---|---|---|---|---|---|
2022-02-25 | L-Cysteinesulfinic acid monohydrate
207121-48-0
|
US $1.90 / g | 1Kg/Bag | 99% | 19tons | Hong Kong Tiansheng New Material Trading Co., Ltd |
- L-Cysteinesulfinic acid monohydrate
207121-48-0
- US $1.90 / g
- 99%
- Hong Kong Tiansheng New Material Trading Co., Ltd