6-Chloro-1,4-dihydro-4-(3-hydroxy-1-pentyn-1-yl)-4-(trifluoromethyl)-2H-3,1-benzoxazin-2-one

6-Chloro-1,4-dihydro-4-(3-hydroxy-1-pentyn-1-yl)-4-(trifluoromethyl)-2H-3,1-benzoxazin-2-one structure

CAS No.: 1627575-39-6

Chemical Name:: 6-Chloro-1,4-dihydro-4-(3-hydroxy-1-pentyn-1-yl)-4-(trifluoromethyl)-2H-3,1-benzoxazin-2-one

Synonyms: 6-Chloro-1,4-dihydro-4-(3-hydroxy-1-pentyn-1-yl)-4-(trifluoromethyl)-2H-3,1-benzoxazin-2-one;2H-3,1-Benzoxazin-2-one, 6-chloro-1,4-dihydro-4-(3-hydroxy-1-pentyn-1-yl)-4-(trifluoromethyl)-

CBNumber:: CB48394217

Molecular Formula:: C14H11ClF3NO3

Molecular Weight:: 333.69

MDL Number:

MOL File:: 1627575-39-6.mol

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6-Chloro-1,4-dihydro-4-(3-hydroxy-1-pentyn-1-yl)-4-(trifluoromethyl)-2H-3,1-benzoxazin-2-one Properties

Boiling point	383.4±42.0 °C(Predicted)
Density	1.50±0.1 g/cm3(Predicted)
pka	10.26±0.40(Predicted)

6-Chloro-1,4-dihydro-4-(3-hydroxy-1-pentyn-1-yl)-4-(trifluoromethyl)-2H-3,1-benzoxazin-2-one Chemical Properties,Uses,Production

Uses

6-Chloro-1,4-dihydro-4-(3-hydroxy-1-pentyn-1-yl)-4-(trifluoromethyl)-2H-3,1-benzoxazin-2-one is an intermediate in the synthesis of (4S)-6-Chloro-1-(1-((S)-6-chloro-2-oxo-4-(trifluoromethyl)-2,4-dihydro-1H-benzo[d][1,3]oxazin-4-yl)pent-1-yn-3-yl)-4-(pent-1-yn-1-yl)-4-(trifluoromethyl)-1H-benzo[d][1,3]oxazin-2(4H)-one (C360050), an impurity of Efavirenz (E425000) which is a nonnucleoside HIV-1 reverse transcriptase inhibitor. Antiviral.

6-Chloro-1,4-dihydro-4-(3-hydroxy-1-pentyn-1-yl)-4-(trifluoromethyl)-2H-3,1-benzoxazin-2-one Preparation Products And Raw materials

Raw materials

Preparation Products

6-Chloro-1,4-dihydro-4-(3-hydroxy-1-pentyn-1-yl)-4-(trifluoromethyl)-2H-3,1-benzoxazin-2-one 2H-3,1-Benzoxazin-2-one, 6-chloro-1,4-dihydro-4-(3-hydroxy-1-pentyn-1-yl)-4-(trifluoromethyl)- 1627575-39-6