ChemicalBook >> CAS DataBase List >>(S)-N-[1-(4-Cyclopropylmethyl-3,4-dihydro-2H-benzo[1,4]oxazin-6-yl)-ethyl]-3-(2-fluoro-phenyl)acrylamide
(S)-N-[1-(4-Cyclopropylmethyl-3,4-dihydro-2H-benzo[1,4]oxazin-6-yl)-ethyl]-3-(2-fluoro-phenyl)acrylamide
![(S)-N-[1-(4-Cyclopropylmethyl-3,4-dihydro-2H-benzo[1,4]oxazin-6-yl)-ethyl]-3-(2-fluoro-phenyl)acrylamide Structure](CAS2/GIF/697287-41-5.gif)
- CAS No.
- 697287-41-5
- Chemical Name:
- (S)-N-[1-(4-Cyclopropylmethyl-3,4-dihydro-2H-benzo[1,4]oxazin-6-yl)-ethyl]-3-(2-fluoro-phenyl)acrylamide
- Synonyms
- (S)-N-[1-(4-Cyclopropylmethyl-3,4-dihydro-2H-benzo[1,4]oxazin-6-yl)-ethyl]-3-(2-fluoro-phenyl)acrylamide;N-[(1S)-1-[4-(CyclopropylMethyl)-3,4-dihydro-2H-1,4-benzoxazin-6-yl]ethyl]-3-(2-fluorophenyl)-2-propenaMide;2-Propenamide, N-[(1S)-1-[4-(cyclopropylmethyl)-3,4-dihydro-2H-1,4-benzoxazin-6-yl]ethyl]-3-(2-fluorophenyl)-
- CBNumber:
- CB51175409
- Molecular Formula:
- C23H25FN2O2
- Molecular Weight:
- 380.46
- MDL Number:
- MOL File:
- 697287-41-5.mol
Last updated:2023-05-15 10:44:01
(S)-N-[1-(4-Cyclopropylmethyl-3,4-dihydro-2H-benzo[1,4]oxazin-6-yl)-ethyl]-3-(2-fluoro-phenyl)acrylamide Properties
| Melting point | 180-182°C |
|---|---|
| Boiling point | 603.4±55.0 °C(Predicted) |
| Density | 1.224±0.06 g/cm3(Predicted) |
| solubility | Dichloromethane (Slightly), DMSO (Slightly), Mehtanol (Slightly) |
| form | Solid |
| pka | 14.27±0.46(Predicted) |
| color | White to Off-White |
(S)-N-[1-(4-Cyclopropylmethyl-3,4-dihydro-2H-benzo[1,4]oxazin-6-yl)-ethyl]-3-(2-fluoro-phenyl)acrylamide price More Price(7)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TRC | C988700 | (S)-N-[1-(4-Cyclopropylmethyl-3,4-dihydro-2H-benzo[1,4]oxazin-6-yl)-ethyl]-3-(2-fluoro-phenyl)acrylamide | 697287-41-5 | 5mg | $645 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | CCH0006618 | (S)-N-(1-(4-CYCLOPROPYLMETHYL-3,4-DIHYDRO-2H-BENZO(1,4)OXAZIN-6-YL)-ETHYL)-3-(2-FLUORO-PHENYL)ACRYLAMIDE 95.00% | 697287-41-5 | 1MG | $739.2 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FC20745 | (S)-N-[1-(4-Cyclopropylmethyl-3,4-dihydro-2H-benzo[1,4]oxazin-6-yl)-ethyl]-3-(2-fluoro-phenyl)acrylamide | 697287-41-5 | 5mg | $840.9 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FC20745 | (S)-N-[1-(4-Cyclopropylmethyl-3,4-dihydro-2H-benzo[1,4]oxazin-6-yl)-ethyl]-3-(2-fluoro-phenyl)acrylamide | 697287-41-5 | 10mg | $1528.8 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | CCH0006618 | (S)-N-(1-(4-CYCLOPROPYLMETHYL-3,4-DIHYDRO-2H-BENZO(1,4)OXAZIN-6-YL)-ETHYL)-3-(2-FLUORO-PHENYL)ACRYLAMIDE 95.00% | 697287-41-5 | 10MG | $1871.1 | 2021-12-16 | Buy |
(S)-N-[1-(4-Cyclopropylmethyl-3,4-dihydro-2H-benzo[1,4]oxazin-6-yl)-ethyl]-3-(2-fluoro-phenyl)acrylamide Chemical Properties,Uses,Production
Chemical Properties
White to Off-White Solid
Uses
A potent and efficacious KCNQ2 opener which inibits induced hyperexcitability of rat hippocampal neurons
Uses
(S)-N-[1-(4-Cyclopropylmethyl-3,4-dihydro-2H-benzo[1,4]oxazin-6-yl)-ethyl]-3-(2-fluoro-phenyl)acrylamide is a potent and efficacious KCNQ2 opener and found to reduce neuronal hyperexcitability in rat hippocampal slices (1).
(S)-N-[1-(4-Cyclopropylmethyl-3,4-dihydro-2H-benzo[1,4]oxazin-6-yl)-ethyl]-3-(2-fluoro-phenyl)acrylamide Preparation Products And Raw materials
Raw materials
Preparation Products
(S)-N-[1-(4-Cyclopropylmethyl-3,4-dihydro-2H-benzo[1,4]oxazin-6-yl)-ethyl]-3-(2-fluoro-phenyl)acrylamide Suppliers
Global( 7)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| J & K SCIENTIFIC LTD. | 010-82848833 400-666-7788 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Chemsky（shanghai）International Co.,Ltd. | 021-50135380 | shchemsky@sina.com | China | 32344 | 50 |
| Shenzhen Polymeri Biochemical Technology Co., Ltd. | +86-400-002-6226 13028896684 | sales@rrkchem.com | China | 55717 | 58 |
| Carbosynth | -- | sales@carbosynth.com | United Kingdom | 6018 | 58 |
| Supplier | Advantage |
|---|---|
| J & K SCIENTIFIC LTD. | 76 |
| Chemsky（shanghai）International Co.,Ltd. | 50 |
| Shenzhen Polymeri Biochemical Technology Co., Ltd. | 58 |
| Carbosynth | 58 |
N-[(1S)-1-[4-(CyclopropylMethyl)-3,4-dihydro-2H-1,4-benzoxazin-6-yl]ethyl]-3-(2-fluorophenyl)-2-propenaMide
(S)-N-[1-(4-Cyclopropylmethyl-3,4-dihydro-2H-benzo[1,4]oxazin-6-yl)-ethyl]-3-(2-fluoro-phenyl)acrylamide
2-Propenamide, N-[(1S)-1-[4-(cyclopropylmethyl)-3,4-dihydro-2H-1,4-benzoxazin-6-yl]ethyl]-3-(2-fluorophenyl)-
697287-41-5
C23H25FN2O2
Inhibitors
All Inhibitors