IONIS-GHR-LRx)
- CAS No.
- 2131025-82-4
- Chemical Name:
- IONIS-GHR-LRx)
- Synonyms
- IONIS-GHR-LRx);Cimdelirsen(Synonyms:ISIS766720
- CBNumber:
- CB513379613
- Molecular Formula:
- Molecular Weight:
- 0
- MDL Number:
- MOL File:
- Mol file
| FDA UNII | F593G1C1YO |
|---|
IONIS-GHR-LRx) Chemical Properties,Uses,Production
Uses
Cimdelirsen is a novel, ligand-conjugated, hepatic-targeted investigative antisense oligonucleotide designed to reduce growth hormone receptor (GHr) synthesis, thereby inhibiting deleterious effects of growth hormone (GH) hypersecretion and reducing circulating insulin-like growth factor-1 (IGF-1) levels in acromegaly patients.
References
[1] Bhanot S, Fleseriu M, Geary R, et al. OR27-4 Placebo-Controlled and Open-Label Extension Study of a Novel Hepatic-Targeted Antisense Cimdelirsen (IONIS-GHR-LRx) Under Investigation in Acromegaly Patients. J Endocr Soc. 2022;6(Suppl 1):A526.
IONIS-GHR-LRx) Preparation Products And Raw materials
Raw materials
Preparation Products
IONIS-GHR-LRx) Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shanghai meikai technology co., ltd | 021-68689288 15300790979 | info@mkbio.com.cn | China | 5000 | 58 |
| Supplier | Advantage |
|---|---|
| Shanghai meikai technology co., ltd | 58 |
