Chinese Japanese Germany Korea
ChemicalBook >> CAS DataBase List >>5-([1,1'-biphenyl]-4-ylmethylene)-2-[4-(2-hydroxyethyl)-1-piperazinyl]-1,3-thiazol-4(5H)-one

5-([1,1'-biphenyl]-4-ylmethylene)-2-[4-(2-hydroxyethyl)-1-piperazinyl]-1,3-thiazol-4(5H)-one

5-([1,1'-biphenyl]-4-ylmethylene)-2-[4-(2-hydroxyethyl)-1-piperazinyl]-1,3-thiazol-4(5H)-one Structure
5-([1,1'-biphenyl]-4-ylmethylene)-2-[4-(2-hydroxyethyl)-1-piperazinyl]-1,3-thiazol-4(5H)-one structure
CAS No.
678158-55-9
Chemical Name:
5-([1,1'-biphenyl]-4-ylmethylene)-2-[4-(2-hydroxyethyl)-1-piperazinyl]-1,3-thiazol-4(5H)-one
Synonyms
CLZ-8;Mcl1-IN-8;Mcl-1-Puma inhibitor 8;Mcl-1-IN-8,Mcl1IN8,Mcl1 IN 8;4(5H)-Thiazolone, 5-([1,1'-biphenyl]-4-ylmethylene)-2-[4-(2-hydroxyethyl)-1-piperazinyl]-;5-([1,1'-biphenyl]-4-ylmethylene)-2-[4-(2-hydroxyethyl)-1-piperazinyl]-1,3-thiazol-4(5H)-one
CBNumber:
CB52056936
Molecular Formula:
C22H23N3O2S
Molecular Weight:
393.5
MDL Number:
MFCD09857618
MOL File:
678158-55-9.mol
Last updated:2023-05-21 10:59:17
Request For Quotation

5-([1,1'-biphenyl]-4-ylmethylene)-2-[4-(2-hydroxyethyl)-1-piperazinyl]-1,3-thiazol-4(5H)-one Properties

Boiling point 596.6±60.0 °C(Predicted)
Density 1.27±0.1 g/cm3(Predicted)
storage temp. Store at -20°C
solubility DMSO: 50 mg/mL (127.06 mM)
pka 14.96±0.10(Predicted)

5-([1,1'-biphenyl]-4-ylmethylene)-2-[4-(2-hydroxyethyl)-1-piperazinyl]-1,3-thiazol-4(5H)-one price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
DC Chemicals DC20444 Mcl-1-Pumainhibitor8 >98% 678158-55-9 100mg $700 2021-12-16 Buy
DC Chemicals DC20444 Mcl-1-Pumainhibitor8 >98% 678158-55-9 250mg $1400 2021-12-16 Buy
Product number Packaging Price Buy
DC20444 100mg $700 Buy
DC20444 250mg $1400 Buy

5-([1,1'-biphenyl]-4-ylmethylene)-2-[4-(2-hydroxyethyl)-1-piperazinyl]-1,3-thiazol-4(5H)-one Chemical Properties,Uses,Production

Description

Mcl-1-PUMA modulator-8 is a modulator of Mcl-1-PUMA interaction which suppresses cancer cells and inhibits PUMA-dependent apoptosis of non-cancerous cells.

5-([1,1'-biphenyl]-4-ylmethylene)-2-[4-(2-hydroxyethyl)-1-piperazinyl]-1,3-thiazol-4(5H)-one Preparation Products And Raw materials

Raw materials

Preparation Products

5-([1,1'-biphenyl]-4-ylmethylene)-2-[4-(2-hydroxyethyl)-1-piperazinyl]-1,3-thiazol-4(5H)-one Suppliers

Global( 11)Suppliers
Supplier Tel Email Country ProdList Advantage
TargetMol Chemicals Inc. 		+1-781-999-5354 +1-00000000000 marketing@targetmol.com United States 19892 58
Aladdin Scientific 		+1-833-552-7181 sales@aladdinsci.com United States 52927 58
Fan De(Beijing) Biotechnology Co., Ltd. 15911056312 liming@bio-fount.com China 9730 58
Shanghai hongqu biomedical technology co. LTD 88888888888 hongquchem@qq.com China 5132 58
TargetMol Chemicals Inc. 4008200310 marketing@tsbiochem.com China 24018 58
Shanghai?Medlife?Pharm-Tech?Co.,?Ltd 021-59167510 18117107507 vip@med-life.cn China 5019 58
RD International Technology Co., Limited 18024082417 market@ubiochem.com China 9180 58
Nanjing Shizhou Biology Technology Co.,Ltd 025-85560043 15850508050 cindy.huang@synzest.com China 12007 58
Supplier Advantage
TargetMol Chemicals Inc. 		58
Aladdin Scientific 		58
Fan De(Beijing) Biotechnology Co., Ltd. 58
Shanghai hongqu biomedical technology co. LTD 58
TargetMol Chemicals Inc. 58
Shanghai?Medlife?Pharm-Tech?Co.,?Ltd 58
RD International Technology Co., Limited 58
Nanjing Shizhou Biology Technology Co.,Ltd 58
5-([1,1'-biphenyl]-4-ylmethylene)-2-[4-(2-hydroxyethyl)-1-piperazinyl]-1,3-thiazol-4(5H)-one Mcl-1-Puma inhibitor 8 Mcl1-IN-8 Mcl-1-IN-8,Mcl1IN8,Mcl1 IN 8 4(5H)-Thiazolone, 5-([1,1'-biphenyl]-4-ylmethylene)-2-[4-(2-hydroxyethyl)-1-piperazinyl]- CLZ-8 678158-55-9