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TAPI-1

CAS No.
163847-77-6
Chemical Name:
TAPI-1
Synonyms
TAPI-1;(2R)-TAPI-1;TAPI-1 acetate salt;TNF-ALPHA PROTEASE INHIBITOR-1;HONHCOCH2CH(CH2-CH(CH3)2)CO-NAL-ALA-NHCH2CH2NH2;N-[(2R)-2-[2-(Hydroxyamino)-2-oxoethyl]-4-methyl-1-oxopentyl]-3-(2-naphthalenyl)--alanyl-L-alaninamide;N-(R)-[2-(HYDROXYAMINOCARBONYL)METHYL]-4-METHYLPENTANOYL-L-NAPHTHYLALANYL-L-ALANINE, 2-AMINOETHYL AMIDE;N-(R)-(2-(HYDROXYAMINOCARBONYL)METHYL)-4-METHYLPENTANOYL-L-3-(2'-NAPHTHYL)ALANYL-L-ALANINE 2-AMINOETHYL AMIDE;L-Alaninamide, N-[(2R)-2-[2-(hydroxyamino)-2-oxoethyl]-4-methyl-1-oxopentyl]-3-(2-naphthalenyl)-L-alanyl-N-(2-aminoethyl)-;N-[(2R)-2-[2-(Hydroxyamino)-2-oxoethyl]-4-methyl-1-oxopentyl]-3-(2-naphthalenyl)-L-alanyl-N-(2-aminoethyl)-L-Alaninamide acetate salt
CBNumber:
CB5206757
Molecular Formula:
C26H37N5O5
Molecular Weight:
499.6
MDL Number:
MFCD02684280
MOL File:
Mol file
MSDS File:
SDS
Last updated:2023-06-30 15:45:59

TAPI-1 Properties

Density 1?+-.0.06 g/cm3(Predicted)
storage temp. Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
pka 9.17±0.20(Predicted)
form powder
color white to beige
FDA UNII UVK3UP3V6Z

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS06
Signal word  Danger
Hazard statements  H301
Precautionary statements  P301+P310
Hazard Codes  T
Risk Statements  25
Safety Statements  45
RIDADR  UN 2811 6.1 / PGIII
WGK Germany  3
HS Code  2928009090

TAPI-1 price More Price(19)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich SML0739 TAPI-1 acetate salt ≥97% (HPLC) 163847-77-6 1mg $393 2024-03-01 Buy
Tocris 6162 TAPI1 ≥95%(HPLC) 163847-77-6 1 $288 2021-12-16 Buy
TRC T731505 TAPI1 163847-77-6 1mg $270 2021-12-16 Buy
ChemScene CS-3108 TAPI-1 ≥99.0% 163847-77-6 1mg $216 2021-12-16 Buy
American Custom Chemicals Corporation INB0000228 TAPI-1 95.00% 163847-77-6 1MG $466.2 2021-12-16 Buy
Product number Packaging Price Buy
SML0739 1mg $393 Buy
6162 1 $288 Buy
T731505 1mg $270 Buy
CS-3108 1mg $216 Buy
INB0000228 1MG $466.2 Buy

TAPI-1 Chemical Properties,Uses,Production

Uses

TAPI-1 acetate salt has been used as a tumor necrosis factor(TNF)-α convertase/ADAM17/α-secretase (TACE) inhibitor.

Biochem/physiol Actions

TAPI-1 is a potent inhibitor of matrix metalloproteinases and TACE (TNF-α convertase/ADAM17/α-secretase).

storage

Store at -20°C

TAPI-1 Preparation Products And Raw materials

Raw materials

Preparation Products

TAPI-1 Suppliers

Global( 80)Suppliers
Supplier Tel Email Country ProdList Advantage
Jilin Chinese Academy of Sciences-yanshen Technology
+undefined18143011203 info@chemextension.com China 42057 58
Aladdin Scientific
+1-833-552-7181 sales@aladdinsci.com United States 52927 58
Haoyuan Chemexpress Co., Ltd. 021-58950125 info@chemexpress.com China 7553 61
MedChemexpress LLC 021-58955995 sales@medchemexpress.cn United States 4863 58
LETOPHARM LIMITED +86-21-5821 5861 sales@letopharm.com China 2384 58
Sigma-Aldrich 021-61415566 800-8193336 orderCN@merckgroup.com China 51471 80
Guangzhou QiYun Biotechnology Co., Ltd. 020-61288194 61288195 505721671@qq.com China 3868 58
ShangHai Biochempartner Co.,Ltd 17754423994 17754423994 2853530910@QQ.com China 8011 62
Shanghai Rechem science Co., Ltd. 21-31433387 15618786686 sales@rechemscience.com China 2983 58
Beijing Solarbio Science & Tecnology Co., Ltd. 010-50973130 4009686088 3193328036@qq.com China 29797 68
HONHCOCH2CH(CH2-CH(CH3)2)CO-NAL-ALA-NHCH2CH2NH2 TAPI-1 N-(R)-(2-(HYDROXYAMINOCARBONYL)METHYL)-4-METHYLPENTANOYL-L-3-(2'-NAPHTHYL)ALANYL-L-ALANINE 2-AMINOETHYL AMIDE N-(R)-[2-(HYDROXYAMINOCARBONYL)METHYL]-4-METHYLPENTANOYL-L-NAPHTHYLALANYL-L-ALANINE, 2-AMINOETHYL AMIDE TNF-ALPHA PROTEASE INHIBITOR-1 N-[(2R)-2-[2-(Hydroxyamino)-2-oxoethyl]-4-methyl-1-oxopentyl]-3-(2-naphthalenyl)-L-alanyl-N-(2-aminoethyl)-L-Alaninamide acetate salt TAPI-1 acetate salt N-[(2R)-2-[2-(Hydroxyamino)-2-oxoethyl]-4-methyl-1-oxopentyl]-3-(2-naphthalenyl)--alanyl-L-alaninamide L-Alaninamide, N-[(2R)-2-[2-(hydroxyamino)-2-oxoethyl]-4-methyl-1-oxopentyl]-3-(2-naphthalenyl)-L-alanyl-N-(2-aminoethyl)- (2R)-TAPI-1 (R)-N1-((S)-1-(((S)-1-((2-Aminoethyl)amino)-1-oxopropan-2-yl)amino)-3-(naphthalen-2-yl)-1-oxopropan-2-yl)-N4-hydroxy-2-isobutylsuccinamide 163847-77-6