ChemicalBook >> CAS DataBase List >>PHA-543613 Dihydrochloride
PHA-543613 Dihydrochloride
- CAS No.
- 478148-58-2
- Chemical Name:
- PHA-543613 Dihydrochloride
- Synonyms
- PHA 543613E;PHA-543613 Dihydrochloride;PHA-543613 Dihydrochloride DISCONTINUED;N-[(3R)-1-Azabicyclo[2.2.2]oct-3-yl]furo[2,3-c]pyridine-5-carboxaMide Dihydrochloride
- CBNumber:
- CB52545557
- Molecular Formula:
- C15H17N3O2
- Molecular Weight:
- 271.31438
- MDL Number:
- MFCD26936338
- MOL File:
- 478148-58-2.mol
Last updated:2023-04-23 13:52:06
Melting point | >300?C |
---|---|
storage temp. | Refrigerator |
solubility | DMSO, Methanol |
form | Solid |
color | Tan |
FDA UNII | Z7950E6X01 |
PHA-543613 Dihydrochloride price More Price(1)
PHA-543613 Dihydrochloride Chemical Properties,Uses,Production
Chemical Properties
Tan Solid
Uses
PHA-543613 is a potent selective α7 nAChR agonist. Nicotinic acetylcholine receptors are ligand-gated ion channels activated by nicotine, expressed in multiple tissues, with high functional expression in brain. The homomeric subtype α7 is a potential therapeutic target for cognitive deficits in schizophrenia and Alzheimer′s disease. PHA-543613 is active in both in vitro (binding, calcium flux, patch-clamp) and in vivo (auditory gating, novel object recognition) assays.
PHA-543613 Dihydrochloride Preparation Products And Raw materials
Raw materials
Preparation Products
PHA-543613 Dihydrochloride Suppliers
Global( 14)Suppliers
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
J & K SCIENTIFIC LTD. | 010-82848833 400-666-7788 | jkinfo@jkchemical.com | China | 96815 | 76 |
Chemsky(shanghai)International Co.,Ltd. | 021-50135380 | shchemsky@sina.com | China | 32344 | 50 |
Shanghai EFE Biological Technology Co., Ltd. | 021-65675885 18964387627 | info@efebio.com | China | 9709 | 58 |
Shenzhen Polymeri Biochemical Technology Co., Ltd. | +86-400-002-6226 13028896684 | sales@rrkchem.com | China | 55717 | 58 |
Energy Chemical | 021-58432009 400-005-6266 | marketing@energy-chemical.com | China | 44941 | 58 |
PHA-543613 Dihydrochloride
N-[(3R)-1-Azabicyclo[2.2.2]oct-3-yl]furo[2,3-c]pyridine-5-carboxaMide Dihydrochloride
PHA 543613E
PHA-543613 Dihydrochloride
DISCONTINUED
478148-58-2
Amines
Heterocycles
Inhibitors
Intermediates & Fine Chemicals
Pfizer compounds
Pharmaceuticals