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O-ButylhydroxylaMine Hydrochloride

CAS No.
4490-82-8
Chemical Name:
O-ButylhydroxylaMine Hydrochloride
Synonyms
BHA.HCl;O-butylhydroxylamine HCl;Butoxyamine hydrochloride;n-Butoxyamine hydrochloride;n-butyloxyamine hydrochloride;O-ButylhydroxylaMine Hydrochloride
CBNumber:
CB52594535
Molecular Formula:
C4H12ClNO
Molecular Weight:
125.59718
MDL Number:
MFCD00487631
MOL File:
4490-82-8.mol
MSDS File:
SDS
Last updated:2026-05-28 03:20:07
Product description Number Pack Size Price
O-Butylhydroxylamine Hydrochloride >98.0%(N)(T) B5686 1g $49
O-Butylhydroxylamine Hydrochloride >98.0%(N)(T) B5686 5g $149
O-Butylhydroxylamine HCl EAA49082 0.25g $250
O-Butylhydroxylamine HCl EAA49082 2.5g $855.5
O-Butylhydroxylamine hydrochloride 98% OR921791 1g $21
More product size

O-ButylhydroxylaMine Hydrochloride Properties

Melting point 157.0 to 161.0 °C
storage temp. under inert gas (nitrogen or Argon) at 2-8°C
solubility soluble in Methanol
form powder to crystal
color White to Almost white

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P264-P280-P305+P351+P338-P337+P313P-P264-P280-P302+P352-P321-P332+P313-P362
HS Code  2928009090
NFPA 704
0
2 0

O-ButylhydroxylaMine Hydrochloride price More Price(41)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TCI Chemical B5686 O-Butylhydroxylamine Hydrochloride >98.0%(N)(T) 4490-82-8 1g $49 2026-04-30 Buy
TCI Chemical B5686 O-Butylhydroxylamine Hydrochloride >98.0%(N)(T) 4490-82-8 5g $149 2026-04-30 Buy
Biosynth EAA49082 O-Butylhydroxylamine HCl 4490-82-8 0.25g $250 2026-06-04 Buy
Biosynth EAA49082 O-Butylhydroxylamine HCl 4490-82-8 2.5g $855.5 2026-06-04 Buy
Apolloscientific OR921791 O-Butylhydroxylamine hydrochloride 98% 4490-82-8 1g $21 2026-06-04 Buy
Product number Packaging Price Buy
B5686 1g $49 Buy
B5686 5g $149 Buy
EAA49082 0.25g $250 Buy
EAA49082 2.5g $855.5 Buy
OR921791 1g $21 Buy

O-ButylhydroxylaMine Hydrochloride Chemical Properties,Uses,Production

Synthesis

1H-Isoindole-1,3(2H)-dione, 2-butoxy-

51951-28-1

O-ButylhydroxylaMine Hydrochloride

4490-82-8

1. 500 mg of hydroxyphthalimide (Aldrich) was dissolved in 5 mL of dimethylformamide (DMF) under argon protection. 2. 0.38 mL of 1-iodobutane (Aldrich) and 0.5 mL of 1,8-diazabicyclo[5.4.0]undec-7-ene (DBU, Aldrich) were added sequentially and slowly. 3. The reaction mixture was stirred at 60 °C for 2 h and subsequently cooled to room temperature. 4. The reaction was terminated by addition of 2 N hydrochloric acid solution and the reaction solution was diluted with 20 mL of ethyl acetate. 5. The organic phase was dried with anhydrous magnesium sulfate, filtered and concentrated under reduced pressure. 6. The residue was purified by silica gel column chromatography using ethyl acetate/hexane (1:5) as eluent to give 635 mg of the target compound (95% yield). 7. The above compound was dissolved in 5 mL of dichloromethane and 0.12 mL of methylhydrazine (TCI) was added slowly at 0 °C. 8. The reaction solution was stirred at room temperature for 2 hours and then cooled to 0°C again. 9. The resulting solid was collected by filtration and 1 mL of 4 M dioxane hydrochloride solution (Aldrich) was added to the filtrate, which was filtered and dried to give 257 mg solid (100% yield). 10. 13 mg of the above solid was dissolved with 44 mg of SAC-0906 in 1 mL of pyridine (Aldrich) under argon protection and stirred at 80 °C for 4 hours. 11. The reaction solution was cooled to room temperature, acidified with 2 N hydrochloric acid solution and extracted with 20 mL of ether. 12. The organic phase was dried with anhydrous magnesium sulfate, filtered and concentrated under reduced pressure. 13. The residue was purified by silica gel column chromatography using ethyl acetate/hexane (1:5) as eluent to afford O-butylhydroxylamine hydrochloride SAC-1015 (44 mg, 88% yield). 14. The product was characterized by 1H-NMR (300 MHz, CDCl3): δ 5.91-5.76 (m, 2H), 5.34-5.33 (m, 1H), 5.28-5.25 (m, 1H), 5.15 (m, 1H), 4.25-4.10 (m, 3H), 4.02-3.97 (m, 2H), 3.59-3.48 (m, 1H), 3.59-3.48 (m, 2H). (m, 1H), 2.42-0.60 (m, 42H).

References

[1] Patent: US2014/378399, 2014, A1. Location in patent: Paragraph 0100
[2] Farmaco, Edizione Scientifica, 1987, vol. 42, # 10, p. 697 - 708
[3] European Journal of Medicinal Chemistry, 2014, vol. 75, p. 184 - 194
[4] Bioorganic and Medicinal Chemistry Letters, 2016, vol. 26, # 7, p. 1844 - 1848

O-ButylhydroxylaMine Hydrochloride Preparation Products And Raw materials

Global( 70)Suppliers
Supplier Tel Email Country ProdList Advantage
career henan chemical co
+86-0371-86658258 +8613203830695 sales@coreychem.com China 29815 58
Alchem Pharmtech,Inc.
8485655694 sales@alchempharmtech.com United States 63687 58
Neostar United (Changzhou) Industrial Co., Ltd.
+86-0519-85551759 +8613506123987 marketing1@neostarunited.com China 8828 58
CD Chemical Group Limited
+8615986615575 info@codchem.com China 17259 58
Henan Alfa Chemical Co., Ltd
+8615838112936 sale03@alfachem.cn China 9796 58
changzhou huayang technology co., ltd
+8615250961469 2571773637@qq.com China 9653 58
Henan Aochuang Chemical Co.,Ltd.
+86-0371-63689365 +8618638391208 sales@aochuangchem.com China 9333 58
HANGZHOU LEAP CHEM CO., LTD.
+86-571-87711850 market18@leapchem.com China 43333 58
Henan Fengda Chemical Co., Ltd
+86-371-86557731 +86-13613820652 info@fdachem.com China 20122 58
Xiamen Work-For-World Medicine Co.,Ltd.
+8615921822462 co@wfwmed.com China 170 58

View Lastest Price from O-ButylhydroxylaMine Hydrochloride manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
O-ButylhydroxylaMine Hydrochloride pictures 2025-04-04 O-ButylhydroxylaMine Hydrochloride
4490-82-8
1KG 98% 1Ton Henan Aochuang Chemical Co.,Ltd.
O-ButylhydroxylaMine Hydrochloride pictures 2019-07-06 O-ButylhydroxylaMine Hydrochloride
4490-82-8
$1.00 1KG 98% 1ton Career Henan Chemical Co

O-ButylhydroxylaMine Hydrochloride Spectrum

O-ButylhydroxylaMine Hydrochloride n-Butoxyamine hydrochloride n-butyloxyamine hydrochloride O-butylhydroxylamine HCl BHA.HCl Butoxyamine hydrochloride 4490-82-8