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ChemicalBook >> CAS DataBase List >>4-Amino-1-[(2R,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]-2(1H)-pyrimidinone

4-Amino-1-[(2R,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]-2(1H)-pyrimidinone

4-Amino-1-[(2R,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]-2(1H)-pyrimidinone Structure
4-Amino-1-[(2R,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]-2(1H)-pyrimidinone structure
CAS No.
136891-12-8
Chemical Name:
4-Amino-1-[(2R,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]-2(1H)-pyrimidinone
Synonyms
4-Amino-1-(cis-2-(hydroxymethyl)-1,3-oxathiolan-5-yl)pyrimidin-2(1H)-one;2(1H)-Pyrimidinone, 4-amino-1-[(2R,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]-, rel-
CBNumber:
CB52657957
Molecular Formula:
C8H11N3O3S
Molecular Weight:
229.26
MDL Number:
MFCD00870542
MOL File:
136891-12-8.mol
Last updated:2023-05-04 17:34:33
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4-Amino-1-[(2R,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]-2(1H)-pyrimidinone Properties

Melting point 187-188℃
Boiling point 475.4±55.0 °C(Predicted)
Density 1.73
storage temp. 2-8°C(protect from light)
pka 13.83±0.10(Predicted)

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H302
Precautionary statements  P280-P305+P351+P338

4-Amino-1-[(2R,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]-2(1H)-pyrimidinone price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Ambeed A133556 4-Amino-1-(cis-2-(hydroxymethyl)-1,3-oxathiolan-5-yl)pyrimidin-2(1H)-one 95+% 136891-12-8 100mg $5 2021-12-16 Buy
Ambeed A133556 4-Amino-1-(cis-2-(hydroxymethyl)-1,3-oxathiolan-5-yl)pyrimidin-2(1H)-one 95+% 136891-12-8 5g $9 2021-12-16 Buy
CSNpharm CSN25469 3-oxathiolane 136891-12-8 100mg $45 2021-12-16 Buy
Chemenu CM249075 4-Amino-1-(cis-2-(hydroxymethyl)-1,3-oxathiolan-5-yl)pyrimidin-2(1H)-one 97% 136891-12-8 500g $411 2021-12-16 Buy
Crysdot CD11270875 4-Amino-1-(cis-2-(hydroxymethyl)-1,3-oxathiolan-5-yl)pyrimidin-2(1H)-one 97% 136891-12-8 500g $436 2021-12-16 Buy
Product number Packaging Price Buy
A133556 100mg $5 Buy
A133556 5g $9 Buy
CSN25469 100mg $45 Buy
CM249075 500g $411 Buy
CD11270875 500g $436 Buy

4-Amino-1-[(2R,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]-2(1H)-pyrimidinone Chemical Properties,Uses,Production

Definition

ChEBI: Lamivudine is a monothioacetal that consists of cytosine having a (2R,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl moiety attached at position 1. An inhibitor of HIV-1 reverse transcriptase, it is used as an antiviral in the treatment of AIDS and hepatitis B. It has a role as a HIV-1 reverse transcriptase inhibitor, an antiviral drug, an anti-HBV agent, an allergen, a prodrug and an EC 2.7.7.49 (RNA-directed DNA polymerase) inhibitor. It is a monothioacetal, a primary alcohol, an oxacycle and a nucleoside analogue. It is functionally related to a cytosine.

4-Amino-1-[(2R,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]-2(1H)-pyrimidinone Preparation Products And Raw materials

Raw materials

Preparation Products

4-Amino-1-[(2R,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]-2(1H)-pyrimidinone Suppliers

Global( 8)Suppliers
Supplier Tel Email Country ProdList Advantage
HANGZHOU CLAP TECHNOLOGY CO.,LTD 		86-571-88216897,88216896 13588875226 sales@hzclap.com CHINA 6313 58
Energy Chemical 021-58432009 400-005-6266 marketing@energy-chemical.com China 44941 58
Lingyuan Bebiansen Biological Technology Co., Ltd 18642120371 2837458851@qq.com China 9925 58
Shanghai Haohong Scientific Co., Ltd. 400-400-8210725 malulu@leyan.com China 40041 58
Supplier Advantage
HANGZHOU CLAP TECHNOLOGY CO.,LTD 		58
Energy Chemical 58
Lingyuan Bebiansen Biological Technology Co., Ltd 58
Shanghai Haohong Scientific Co., Ltd. 58
2(1H)-Pyrimidinone, 4-amino-1-[(2R,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]-, rel- 4-Amino-1-(cis-2-(hydroxymethyl)-1,3-oxathiolan-5-yl)pyrimidin-2(1H)-one 136891-12-8