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rolapitant intermediate
- CAS No.
- 873947-10-5
- Chemical Name:
- rolapitant intermediate
- Synonyms
- NK-1 Antagonist 1;NK 1 Antagonist 1,NK1 Antagonist 1;3-Piperidinecarbonitrile, 6-[[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]methyl]-3-(1,5-dihydro-5-oxo-4H-1,2,4-triazol-4-yl)-6-phenyl-, (3S,6S)-
- CBNumber:
- CB53373014
- Molecular Formula:
- C25H23F6N5O2
- Molecular Weight:
- 539.47
- MDL Number:
- MFCD31692346
- MOL File:
- 873947-10-5.mol
Last updated:2025-04-17 18:22:24
| storage temp. | Store at -20°C |
|---|---|
| solubility | Soluble in DMSO |
| FDA UNII | Q2B1Q52A8J |
rolapitant intermediate Chemical Properties,Uses,Production
Uses
SCH 900978 (NK-1 Antagonist 1) is an antagonist of NK-1 receptor, used in the research of NK-1 related diseases and conditions such as cough, overactive bladder, alcohol dependency and depression[1].
References
[1] Jane H. Hsiao, et al. Heteroaryl carbonitriles for the treatment of disease. WO2017011445A1.
rolapitant intermediate Preparation Products And Raw materials
Raw materials
Preparation Products
rolapitant intermediate Suppliers
Global( 8)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| TargetMol Chemicals Inc. | +1-781-999-5354; +17819995354 | marketing@targetmol.com | United States | 32435 | 58 |
| Jinan Yaoyan Pharmaceutical Co., Ltd. | jnyaoyan@163.com | China | 3069 | 58 | |
| Fan De(Beijing) Biotechnology Co., Ltd. | 15911056312 | liming@bio-fount.com | China | 9729 | 58 |
| Nanjing Meihao Pharmaceutical Technology Co., Ltd. | meitaochem@126.com | meitaochem@126.com | China | 19103 | 58 |
| Beijing Jin Ming Biotechnology Co., Ltd. | 010-60605840 15801484223; | psaitong@jm-bio.com | China | 29757 | 58 |
| TargetMol Chemicals Inc. | 15002134094 | marketing@targetmol.cn | China | 29257 | 58 |
| Biosynth Biological Technology (Suzhou) Co Ltd | 51288865780 | sales@biosynth.com | China | 6051 | 58 |
| Adooq Bioscience LLC | 400-025-6535 | sales@adooq.cn | China | 6215 | 58 |
NK-1 Antagonist 1
3-Piperidinecarbonitrile, 6-[[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]methyl]-3-(1,5-dihydro-5-oxo-4H-1,2,4-triazol-4-yl)-6-phenyl-, (3S,6S)-
NK 1 Antagonist 1,NK1 Antagonist 1
873947-10-5
C25H23F6N5O2
