ChemicalBook >> CAS DataBase List >>6-Methylthioguanine
6-Methylthioguanine
- CAS No.
- 1198-47-6
- Chemical Name:
- 6-Methylthioguanine
- Synonyms
- NSC 29420;TIMTEC-BB SBB000228;6-Methylthioguanine;S-Methyl-6-thioguanine;S6-Methyl-6-thioguanine;2-Amino-6-methylthiopurine;Mercaptopurine Impurity 29;6-Methylthioguanine USP/EP/BP;2-AMINO-6-METHYLMERCAPTOPURINE;6-Methylthio-7H-purine-2-amine
- CBNumber:
- CB5468494
- Molecular Formula:
- C6H7N5S
- Molecular Weight:
- 181.22
- MDL Number:
- MFCD00044701
- MOL File:
- 1198-47-6.mol
- MSDS File:
- SDS
Last updated:2023-05-04 17:34:32
| Melting point | 235.5°C |
|---|---|
| Density | 1.403 (estimate) |
| refractive index | 1.4606 (estimate) |
| storage temp. | -20°C Freezer |
| solubility | DMSO (Slightly), Methanol (Slightly, Sonicated) |
| form | solid |
| color | White to Off-White |
| FDA UNII | QNV75HJN3A |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS05,GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H302-H315-H318-H335 | |||||||||
| Precautionary statements | P280-P301+P312+P330-P302+P352-P305+P351+P338+P310 | |||||||||
| Hazard Codes | Xn | |||||||||
| Risk Statements | 22-37/38-41 | |||||||||
| Safety Statements | 24/25-39-26 | |||||||||
| WGK Germany | 3 | |||||||||
| HS Code | 29335995 | |||||||||
| NFPA 704 |
|
6-Methylthioguanine price More Price(14)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | A9546 | 2-Amino-6-methylmercaptopurine ≥95% | 1198-47-6 | 100mg | $126 | 2024-03-01 | Buy |
| Usbiological | 017448 | 6-Methylthioguanine | 1198-47-6 | 250mg | $496 | 2021-12-16 | Buy |
| TRC | M330720 | 6-Methylthioguanine | 1198-47-6 | 1g | $660 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | CHM0027598 | 2-AMINO-6-METHYLMERCAPTOPURINE 95.00% | 1198-47-6 | 250MG | $779.63 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | CHM0027598 | 2-AMINO-6-METHYLMERCAPTOPURINE 95.00% | 1198-47-6 | 2.5G | $2255 | 2021-12-16 | Buy |
6-Methylthioguanine Chemical Properties,Uses,Production
Chemical Properties
off-white crystalline powder
Uses
2-Amino-6-methylmercaptopurine is a 2-amino-6-alkyldithiopurine that has been used with other 6-position carbon analogues to study brain specific diazepam binding.
Uses
As a metabolite of 2’-Deoxy-6-thio Guanosine (D281650) and 6-Thioguanine, 6-Methylthioguanine can be used as an effective immunosuppressant and anticancer agent, however chronic exposure can be mutagenic in human cells as long-term use of thiopurines was found to be associated with a significantly increased risk of various types of cancer.
Definition
ChEBI: 6-methylthioguanine is a metabolite of thioguanine, a drug used in cancer chemotherapy. It has a role as a human xenobiotic metabolite. It is a member of 2-aminopurines and a thiopurine. It is functionally related to a tioguanine.
Biochem/physiol Actions
2-Amino-6-methylmercaptopurine is synthesized from 6-mercaptopurine by the S methylation activity of thiopurine methyl transferase (TMPT) enzyme.
6-Methylthioguanine Preparation Products And Raw materials
Global( 67)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hubei xin bonus chemical co. LTD | 86-13657291602 | linda@hubeijusheng.com | CHINA | 22968 | 58 |
| Career Henan Chemica Co | +86-0371-86658258 15093356674; | laboratory@coreychem.com | China | 30255 | 58 |
| Hefei TNJ Chemical Industry Co.,Ltd. | 0551-65418671 | sales@tnjchem.com | China | 34572 | 58 |
| Dideu Industries Group Limited | +86-29-89586680 +86-15129568250 | 1026@dideu.com | China | 29220 | 58 |
| Dayang Chem (Hangzhou) Co.,Ltd. | 571-88938639 +8617705817739 | info@dycnchem.com | CHINA | 52867 | 58 |
| GIHI CHEMICALS CO.,LIMITED | +8618058761490 | info@gihichemicals.com | China | 49999 | 58 |
| Shanghai Acmec Biochemical Technology Co., Ltd. | +undefined18621343501 | product@acmec-e.com | China | 33349 | 58 |
| Aladdin Scientific | +1-833-552-7181 | sales@aladdinsci.com | United States | 57511 | 58 |
| J & K SCIENTIFIC LTD. | 010-82848833 400-666-7788 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Meryer (Shanghai) Chemical Technology Co., Ltd. | 4006608290; 18621169109 | market03@meryer.com | China | 40241 | 62 |
1198-47-6(6-Methylthioguanine)Related Search:
8-AZA-6-HYDROXY-2-MERCAPTOPURINE
6-thioinosine-5'-triphosphate
6,8-DIHYDROXY-2-METHYLMERCAPTOPURINE
2-Amino-6-mercaptopurine-13C2,15N
6-N-HEPTYLMERCAPTOPURINE
1,9-DIHYDRO-6H-PURINE-6-THIONE
2-AMINO-9-(2,3,5-TRI-O-ACETYL-BETA-D-RIBOFURANOSYL)-6-THIOPURINE
6-(Methylthio)purine
2-AMINO-6-HYDROXY-8-MERCAPTOPURINE
1,7,8,9-tetrahydro-8-thioxo-6H-purin-6-one
1of4
1H-Purin-2-amine, 6-(methylthio)-
2-Amino-6-methylthiopurine
6-(Methylsulfanyl)-1H-purin-2-amine
6-Methylthioguanine
TIMTEC-BB SBB000228
6-(METHYLSULFANYL)-7H-PURIN-2-YLAMINE
2-AMINO-6-METHYLMERCAPTOPURINE
2-AMINO-6-METHYLMERCAPTOPURINE 95%
2-Amino-6-(methylthio)-9H-purine
6-(Methylthio)-9H-purine-2-amine
6-Methylthio-7H-purine-2-amine
2-Amino-6-methylmercaptopurine,95%
NSC 29420
S6-Methyl-6-thioguanine
S-Methyl-6-thioguanine
6-(methylthio)-1H-purin-2-amine
2-Amino-6-methylmercaptopurine-[13C, d3] (Solution)
9H-Purin-2-amine, 6-(methylthio)-
Mercaptopurine Impurity 29
6-Methylthioguanine USP/EP/BP
6-(methylsulfanyl)-7H-purin-2-amine
6-(Methylthio)-7H-purin-2-amine
1198-47-6
C6H7N5S
Biochemicals and Reagents
BioChemical
Nucleoside Analogs
Nucleosides, Nucleotides, Oligonucleotides
Heterocycles, Metabolites & Impurities, Nucleotides, Bases & Related Reagents, Mutagenesis Research Chemicals, Sulfur & Selenium Compounds
Bases & Related Reagents
Heterocycles
Metabolites & Impurities
Mutagenesis Research Chemicals
Nucleotides
Sulfur & Selenium Compounds