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6-Methylthioguanine

6-Methylthioguanine
6-Methylthioguanine structure
CAS No.
1198-47-6
Chemical Name:
6-Methylthioguanine
Synonyms
NSC 29420;TIMTEC-BB SBB000228;6-Methylthioguanine;S-Methyl-6-thioguanine;S6-Methyl-6-thioguanine;2-Amino-6-methylthiopurine;Mercaptopurine Impurity 29;6-Methylthioguanine USP/EP/BP;2-AMINO-6-METHYLMERCAPTOPURINE;6-Methylthio-7H-purine-2-amine
CBNumber:
CB5468494
Molecular Formula:
C6H7N5S
Formula Weight:
181.22
MOL File:
1198-47-6.mol

6-Methylthioguanine Properties

Melting point:
235.5°C
Density 
1.403 (estimate)
refractive index 
1.4606 (estimate)
form 
solid
FDA UNII
QNV75HJN3A
SAFETY
  • Risk and Safety Statements
Symbol(GHS) 
GHS05,GHS07
Signal word  Danger
Hazard statements  H302-H315-H318-H335
Precautionary statements  P261-P280-P305+P351+P338
Hazard Codes  Xn
Risk Statements  22-37/38-41
Safety Statements  24/25-39-26
WGK Germany  3
HS Code  29335995
NFPA 704
1
2 0

6-Methylthioguanine price More Price(14)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich A9546 2-Amino-6-methylmercaptopurine ≥95% 1198-47-6 100mg $99.5 2021-12-16 Buy
Usbiological 017448 6-Methylthioguanine 1198-47-6 250mg $496 2021-12-16 Buy
TRC M330720 6-Methylthioguanine 1198-47-6 1g $660 2021-12-16 Buy
American Custom Chemicals Corporation CHM0027598 2-AMINO-6-METHYLMERCAPTOPURINE 95.00% 1198-47-6 250MG $779.63 2021-12-16 Buy
American Custom Chemicals Corporation CHM0027598 2-AMINO-6-METHYLMERCAPTOPURINE 95.00% 1198-47-6 2.5G $2255 2021-12-16 Buy

6-Methylthioguanine Chemical Properties,Uses,Production

Chemical Properties

off-white crystalline powder

Uses

As a metabolite of 2’-Deoxy-6-thio Guanosine (D281650) and 6-Thioguanine, 6-Methylthioguanine can be used as an effective immunosuppressant and anticancer agent, however chronic exposure can be mutagenic in human cells as long-term use of thiopurines was found to be associated with a significantly increased risk of various types of cancer.

Uses

2-Amino-6-methylmercaptopurine is a 2-amino-6-alkyldithiopurine that has been used with other 6-position carbon analogues to study brain specific diazepam binding.

Biochem/physiol Actions

2-Amino-6-methylmercaptopurine is synthesized from 6-mercaptopurine by the S methylation activity of thiopurine methyl transferase (TMPT) enzyme.

6-Methylthioguanine Preparation Products And Raw materials

Raw materials

Preparation Products


6-Methylthioguanine Suppliers

Global( 48)Suppliers
Supplier Tel Fax Email Country ProdList Advantage
Hubei xin bonus chemical co. LTD
86-13657291602
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Career Henan Chemica Co
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Dideu Industries Group Limited
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Dayang Chem (Hangzhou) Co.,Ltd.
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J & K SCIENTIFIC LTD. 400-666-7788 010-82848833-
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Meryer (Shanghai) Chemical Technology Co., Ltd. 400-660-8290 21-61259100-
86-21-61259102 sh@meryer.com China 40264 62
Nanjing Chemlin Chemical Co., Ltd 025-83697070
+86-25-83453306 info@chemlin.com.cn China 20007 64
Chemsky (shanghai) International Co.,Ltd 021-50135380
shchemsky@sina.com China 15424 60
Chengdu Ai Keda Chemical Technology Co., Ltd. 4008-755-333 028-85911938-
028-86757656 800078821@qq.com China 9750 55

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