7Α,24(S)-DIHYDROXYCHOLESTEROL

CAS No.
245523-67-5
Chemical Name:
7Α,24(S)-DIHYDROXYCHOLESTEROL
Synonyms
7Α,24(S)-DIHYDROXYCHOLESTEROL;7alpha,24(S)-dihydroxycholesterol;Cholest-5-ene-3,7,24-triol, (3β,7α,24S)-
CBNumber:
CB54743667
Molecular Formula:
C27H46O3
Molecular Weight:
418.65
MDL Number:
MFCD22416740
MOL File:
245523-67-5.mol

7Α,24(S)-DIHYDROXYCHOLESTEROL Properties

Boiling point 548.5±35.0 °C(Predicted)
Density 1.08±0.1 g/cm3(Predicted)
storage temp. -20°C
pka 14.10±0.70(Predicted)

7Α,24(S)-DIHYDROXYCHOLESTEROL Chemical Properties,Uses,Production

Uses

7α,24(S)-Dihydroxycholesterol is a sterol found to be,one of several, the most abundant cholesterol metabolite and an intermediate of bile acid biosynthetic pathways.

General Description

7α,24(S)-dihydroxycholesterol (24(S)-dihydroxycholesterol) is synthetically synthesized via from E-α, β-enone from the starting compounds Arsonium ylide and J-tert-butyldimethylsilyloxy-bisnor-5-cholenaldehyde. This undergoes further changes to form 7α,24(S)-dihydroxycholesterol.

Biochem/physiol Actions

7α,24(S)-dihydroxycholesterol (24(S)-dihydroxycholesterol) is a ligand for liver X receptor (LXR) and binds to the ligand binding domain of LXRα and LXRβ.

7Α,24(S)-DIHYDROXYCHOLESTEROL Preparation Products And Raw materials

Raw materials

Preparation Products

7Α,24(S)-DIHYDROXYCHOLESTEROL Suppliers

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7alpha,24(S)-dihydroxycholesterol 7Α,24(S)-DIHYDROXYCHOLESTEROL Cholest-5-ene-3,7,24-triol, (3β,7α,24S)- 245523-67-5