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RITODRINE

CAS No.
26652-09-5
Chemical Name:
RITODRINE
Synonyms
Lavopa;Premar;RITODRINE;ritodrina;Formoterol-d;RITODRINE USP/EP/BP;Phenoxybenzamine hydrochl;Ritodrine Impurity 2 (Ritodrine);(1R,2S)-2-(4-Hydroxyphenethylamino)-1-(4-hydroxyphenyl)-1-propanol;4-[(1R,2S)-1-Hydroxy-2-[2-(4-hydroxyphenyl)ethylamino]propyl]phenol
CBNumber:
CB5476882
Molecular Formula:
C17H21NO3
Molecular Weight:
287.35
MDL Number:
MFCD00869731
MOL File:
26652-09-5.mol
MSDS File:
SDS
Last updated:2023-05-04 17:34:36

RITODRINE Properties

Melting point 88-90 °C
Boiling point 512.3±45.0 °C(Predicted)
Density 1.213±0.06 g/cm3(Predicted)
pka pKa 9.0 (Uncertain)
FDA UNII I0Q6O6740J
ATC code G02CA01

RITODRINE price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Usbiological R2032-20B Ritodrine 26652-09-5 500ul $393 2021-12-16 Buy
American Custom Chemicals Corporation API0009207 RITODRINE 95.00% 26652-09-5 250MG $627.24 2021-12-16 Buy
American Custom Chemicals Corporation API0009207 RITODRINE 95.00% 26652-09-5 1G $857.66 2021-12-16 Buy
American Custom Chemicals Corporation API0009207 RITODRINE 95.00% 26652-09-5 5G $1603.26 2021-12-16 Buy
Product number Packaging Price Buy
R2032-20B 500ul $393 Buy
API0009207 250MG $627.24 Buy
API0009207 1G $857.66 Buy
API0009207 5G $1603.26 Buy

RITODRINE Chemical Properties,Uses,Production

Description

Ritodrine, 4-hydroxy-α-[1-[(4′-hydroxyphenethyl)amino]ethyl]benzylic alcohol (11.1.19), differs slightly from epinephrine, and in the given example only one hydroxyl group has been added to the aromatic ring of the phenylethylamino region of classic sympathomimetics. The second major difference between the examined series is the replacement of the traditionally terminal iso-propyl or tert-butylamine region with a p-hydroxyphenylethylamine. Finally, the third difference is the presence of a methyl group at the α-atom of the phenylethylamine region of sympathomimetics, which makes it similar to isoetharine.

Uses

Relaxant (smooth muscle).

Uses

Ritodrine is a selective β2-adrenoreceptor stimulant, predominantly of the urino-genital system. It is used as a tocolytic agent for problems associated with premature miscarriages, and only in specialized medical facilities.

Definition

ChEBI: (1S,2R)-ritodrine is a 4-[2-[[1-hydroxy-1-(4-hydroxyphenyl)propan-2-yl]amino]ethyl]phenol that has (1S,2R)-configuration. It is an enantiomer of a (1R,2S)-ritodrine.

General Description

Ritodrine is a selective β2-agonist that wasdeveloped specifically for use as a uterine relaxant. Its uterineinhibitory effects are more sustained than its effects onthe cardiovascular system, which are minimal comparedwith those caused by nonselective β-agonists. The cardiovasculareffects usually associated with its administrationare mild tachycardia and slight diastolic pressure decrease.Usually, it is administered initially by intravenous infusionto stop premature labor and subsequently it may be givenorally.

Clinical Use

Ritodrine is a selective β2-agonist that is used exclusively for relaxing uterine muscle and inhibiting the contractions of premature labor. Terbutaline, in addition to its use as a bronchodilator, also has been used for halting the contractions of premature labor.

Synthesis

Ritodrine is synthesized from 4-benzyloxypropiophenone, which undergoes bromination into 4-benzyloxy-|á-bromopropiophenone (11.1.17). This is reacted with 2-(4-benzyloxyphenyl)ethylamine, forming an intermediate product (11.1.18), which undergoes further debenzylation by hydrogen using a palladium catalyst, giving ritodrine (11.1.19) [24,25].

Synthesis_26652-09-5

RITODRINE Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 48)Suppliers
Supplier Tel Email Country ProdList Advantage
Shaanxi Dideu Medichem Co. Ltd
+86-029-89586680 +86-18192503167 1026@dideu.com China 9126 58
Dideu Industries Group Limited
+86-29-89586680 +86-15129568250 1026@dideu.com China 28251 58
ZHEJIANG JIUZHOU CHEM CO., LTD
+86-0576225566889 +86-13454675544 admin@jiuzhou-chem.com;jamie@jiuzhou-chem.com;alice@jiuzhou-chem.com China 19949 58
Guangzhou PI PI Biotech Inc +86-020-81716320 +86-13602409664 Sales@pipitech.com China 3635 55
LGM Pharma 1-(800)-881-8210 inquiries@lgmpharma.com United States 2127 70
ChemStrong Scientific Co.,Ltd 0755-0755-66853366 13670046396 sales@chem-strong.com China 17993 56
Roark Standards 0755-83552066 15986688328 service@roarkstandards.com China 1443 58
PI & PI BIOTECH INC. 020-81716320 17788709170 Sales@pipitech.com China 2649 58
Chengdu Saint - Kay Biotechnology Co., Ltd. 028-85157043 15882256948 676046971@qq.com China 4393 58
TargetMol Chemicals Inc. 4008200310 marketing@tsbiochem.com China 24018 58

View Lastest Price from RITODRINE manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
RITODRINE pictures 2024-04-17 RITODRINE
26652-09-5
US $1.10 / g 1g 99.0% min 100 tons min Shaanxi Dideu Medichem Co. Ltd
Ritodrine pictures 2024-04-10 Ritodrine
26652-09-5
US $0.00-0.00 / mg 10mg 90%+ 10g Guangzhou PI PI BIOTECH INC
RITODRINE USP/EP/BP pictures 2021-06-02 RITODRINE USP/EP/BP
26652-09-5
US $1.10 / g 1g 99.9% 100Tons min Dideu Industries Group Limited
  • RITODRINE pictures
  • RITODRINE
    26652-09-5
  • US $1.10 / g
  • 99.0% min
  • Shaanxi Dideu Medichem Co. Ltd
  • Ritodrine pictures
  • Ritodrine
    26652-09-5
  • US $0.00-0.00 / mg
  • 90%+
  • Guangzhou PI PI BIOTECH INC
4-hydroxy-alpha-(1-((2-(4-hydroxyphenyl)ethyl)amino)ethyl)-benzenemethano( 4-hydroxy-alpha-(1-((2-(4-hydroxyphenyl)ethyl)amino)ethyl)benzenemethanol(r* erythro-p-hydroxy-alpha-(1-((p-hydroxyphenethyl)amino)ethyl)benzylalcohol RITODRINE Benzenemethanol, 4-hydroxy-a-[(1R)-1-[[2-(4-hydroxyphenyl)ethyl]amino]ethyl]-, (aS)-rel- (9CI) Benzenemethanol, 4-hydroxy-a-[1-[[2-(4-hydroxyphenyl)ethyl]amino]ethyl]-, (R*,S*)- Benzyl alcohol, p-hydroxy-a-[1-[(p-hydroxyphenethyl)amino]ethyl]-, erythro- (8CI) (1R,2S)-1-(4-Hydroxyphenyl)-2-[(4-hydroxyphenethyl)amino]-1-propanol (1R,2S)-2-(4-Hydroxyphenethylamino)-1-(4-hydroxyphenyl)-1-propanol (1R,2S)-2-[(4-Hydroxyphenethyl)amino]-1-(4-hydroxyphenyl)-1-propanol (αR)-4-Hydroxy-α-[(S)-1-[[2-(4-hydroxyphenyl)ethyl]amino]ethyl]benzenemethanol (αR)-p-Hydroxy-α-[(S)-1-[(p-hydroxyphenethyl)amino]ethyl]benzyl alcohol Lavopa Premar 4-[(1R,2S)-1-Hydroxy-2-[2-(4-hydroxyphenyl)ethylamino]propyl]phenol p-hydroxy-alpha-(1-((p-hydroxyphenethyl)amino)ethyl)-benzylalcohoerythr ritodrina Ritodrine Impurity 2 (Ritodrine) RITODRINE USP/EP/BP Benzenemethanol, 4-hydroxy-α-[(1R)-1-[[2-(4-hydroxyphenyl)ethyl]amino]ethyl]-, (αS)-rel- 4-[2-[[(1S,2R)-1-hydroxy-1-(4-hydroxyphenyl)propan-2-yl]amino]ethyl]phenol Phenoxybenzamine hydrochl Formoterol-d 26652-09-5