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4' 5'-BIS(N N-BIS(CARBOXYMETHYL)AMINO-

CAS No.
207124-64-9
Chemical Name:
4' 5'-BIS(N N-BIS(CARBOXYMETHYL)AMINO-
Synonyms
Calcein tetraethyl acid;Calceintetraethylacid, >97%;4' 5'-BIS(N N-BIS(CARBOXYMETHYL)AMINO-;Glycine, N,N'-[(3',6'-dihydroxy-3-oxospiro[isobenzofuran-1(3H),9'-[9H]xanthene]-4',5'-diyl)bis(methylene)]bis[N-(carboxymethyl)-;2,2',2'',2'''-(((3',6'-Dihydroxy-3-oxo-3H-spiro[isobenzofuran-1,9'-xanthene]-4',5'-diyl)bis(methylene))bis(azanetriyl))tetraacetic acid;3H-IndoliuM, 2-[3-[1,3-dihydro-3,3-diMethyl-1-[6-oxo-6-(2-propyn-1-ylaMino)hexyl]-5-sulfo-2H-indol-2-ylidene]-1-propen-1-yl]-1-ethyl-3,3-diMethyl-5-sulfo-coMpd. with N,N-diethylethanaMine (1:2)
CBNumber:
CB5503814
Molecular Formula:
C30H26N2O13
Molecular Weight:
622.53
MDL Number:
MFCD00075616
MOL File:
207124-64-9.mol
Last updated:2023-05-15 10:43:59

4' 5'-BIS(N N-BIS(CARBOXYMETHYL)AMINO- Properties

solubility DMSO (Slightly, Heated), Methanol (Slightly, Heated, Sonicated)
form Solid
color Yellow to Dark Yellow

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P271-P280
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  26-37/39
HS Code  2922500090

4' 5'-BIS(N N-BIS(CARBOXYMETHYL)AMINO- Chemical Properties,Uses,Production

Uses

Fluorescein Bis(methylene)]bis[N-(carboxymethyl)glycine] is an intermediate used in the synthesis of Calcein AM (C125400), which is a hydrophobic non-fluorescent probe that can permeate the plasma membrane and can be hydrolyzed to Calcein (sc-202090), which is an extremely fluorescent and negatively charged molecule. Calcein-AM can be used to stain living cells and in cytoplasmic Schwann cells has been observed to fluoresce bright green. Calcein-AM has been reported to be a neutral substrate for P-glycoprotein (Pgp) and multidrug resistance protein (MRP) and has been used in flow cytometry studies to analyze the function of P-gp and MRP.

4' 5'-BIS(N N-BIS(CARBOXYMETHYL)AMINO- Preparation Products And Raw materials

Raw materials

Preparation Products

4' 5'-BIS(N N-BIS(CARBOXYMETHYL)AMINO- Suppliers

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4' 5'-BIS(N N-BIS(CARBOXYMETHYL)AMINO- 3H-IndoliuM, 2-[3-[1,3-dihydro-3,3-diMethyl-1-[6-oxo-6-(2-propyn-1-ylaMino)hexyl]-5-sulfo-2H-indol-2-ylidene]-1-propen-1-yl]-1-ethyl-3,3-diMethyl-5-sulfo-coMpd. with N,N-diethylethanaMine (1:2) Calcein tetraethyl acid Calceintetraethylacid, >97% Glycine, N,N'-[(3',6'-dihydroxy-3-oxospiro[isobenzofuran-1(3H),9'-[9H]xanthene]-4',5'-diyl)bis(methylene)]bis[N-(carboxymethyl)- 2,2',2'',2'''-(((3',6'-Dihydroxy-3-oxo-3H-spiro[isobenzofuran-1,9'-xanthene]-4',5'-diyl)bis(methylene))bis(azanetriyl))tetraacetic acid 207124-64-9 marker