N-(Azido-PEG3)-N-bis(PEG4-Boc)
- CAS No.
- 2353409-58-0
- Chemical Name:
- N-(Azido-PEG3)-N-bis(PEG4-Boc)
- Synonyms
- N3-PEG3-N-(PEG4-COOtBu)2;N-(Azido-PEG3)-N-bis(PEG4-Boc);N-(Azido-PEG3)-N-bis(PEG4-t-butyl ester)
- CBNumber:
- CB58054765
- Molecular Formula:
- C38H74N4O15
- Molecular Weight:
- 827.02
- MDL Number:
- MFCD31811450
- MOL File:
- 2353409-58-0.mol
| Product description | Number | Pack Size | Price |
| N-(Azido-PEG3)-N-bis(PEG4-t-butylester) 98% | BP-24285 | 250mg | $580 |
| N-(Azido-PEG3)-N-bis(PEG4-t-butylester) 98% | BP-24285 | 500mg | $980 |
N-(Azido-PEG3)-N-bis(PEG4-Boc) price
N-(Azido-PEG3)-N-bis(PEG4-Boc) Chemical Properties,Uses,Production
Description
N-(Azido-PEG3)-N-bis(PEG4-t-butyl ester) is a branched conjugation reagent with a terminal azide group. The azide group enables PEGylation via Click Chemistry. The t-butyl protected carboxyl groups can be deprotected under mild acidic conditions.
Uses
N-(Azido-PEG3)-N-bis(PEG4-Boc) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. N-(Azido-PEG3)-N-bis(PEG4-Boc) is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
IC 50
PEGs
References
[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005
N-(Azido-PEG3)-N-bis(PEG4-Boc) Preparation Products And Raw materials
Raw materials
Preparation Products
N-(Azido-PEG3)-N-bis(PEG4-Boc) Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| TargetMol Chemicals Inc. | +1-781-999-5354; +17819995354 | marketing@targetmol.com | United States | 32435 | 58 |
| Alfa Chemistry | +1-5166625404; | Info@alfa-chemistry.com | United States | 20405 | 58 |
| Hangzhou MolCore BioPharmatech Co.,Ltd. | +86-057181025280; +8617767106207 | sales@molcore.com | China | 49734 | 58 |
| Jilin Chinese Academy of Sciences-yanshen Technology | +undefined18143011203 | info@chemextension.com | China | 42056 | 58 |
| Aladdin Scientific | tp@aladdinsci.com | United States | 52923 | 58 | |
| Jilin Chinese Academy of Sciences - Yanshen Technology Co., Ltd | 0431-0431-80514535 19917294565 | et@chemextension.com | China | 3935 | 55 |
| Xi'an Confluore Biological Technology Co., Ltd. | +86-156-80926068 +86-15680926068 | 1924344760@qq.com | China | 4952 | 58 |
| Nanjing Shizhou Biology Technology Co.,Ltd | 025-85563444 18351873721 | purchase@synzest.com | China | 10434 | 58 |
| Zhengzhou Akem Chemical Co., Ltd | 13303867194 | 3001317055@qq.com | China | 9682 | 58 |
| Beijing Jin Ming Biotechnology Co., Ltd. | 010-60605840 15801484223; | psaitong@jm-bio.com | China | 29757 | 58 |
