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bassianolide

CAS No.
64763-82-2
Chemical Name:
bassianolide
Synonyms
bassianolide;(-)-Bassianolide;BASSIANOLIDE,>95% BY HPLC;4,10,16,22-tetramethyl-3,9,15,21-tetrakis(2-methylpropyl)-6,...;Cyclo[D-Hmb-N-methyl-L-Leu-D-Hmb-N-methyl-L-Leu-D-Hmb-N-methyl-L-Leu-D-Hmb-N-methyl-L-Leu-];4,10,16,22-tetramethyl-3,9,15,21-tetrakis(2-methylpropyl)-6,12,18,24-tetra(propan-2-yl)-1,7,13,19-tetraoxa-4,10,16,22-tetraazacyclotetracosane-2,5,8,11,14,17,20,23-octone;Cyclo[(2R)-2-hydroxy-3-methylbutanoyl-N-methyl-L-leucyl-(2R)-2-hydroxy-3-methylbutanoyl-N-methyl-L-leucyl-(2R)-2-hydroxy-3-methylbutanoyl-N-methyl-L-leucyl-(2R)-2-hydroxy-3-methylbutanoyl-N-methyl-L-leucyl]
CBNumber:
CB61330306
Molecular Formula:
C48H84N4O12
Molecular Weight:
909.2
MDL Number:
MFCD28898444
MOL File:
64763-82-2.mol
MSDS File:
SDS
Last updated:2023-05-04 17:34:41

bassianolide Properties

Boiling point 1015.6±65.0 °C(Predicted)
Density 1.012±0.06 g/cm3(Predicted)
solubility DMF: Soluble; DMSO: Soluble; Ethanol: Soluble; Methanol: Soluble
form A solid
pka -0.84±0.70(Predicted)
FDA UNII 806ADE0Q38

bassianolide price More Price(3)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 22001 Bassianolide ≥95% 64763-82-2 500μg $311 2024-03-01 Buy
Cayman Chemical 22001 Bassianolide ≥95% 64763-82-2 2.5mg $1394 2024-03-01 Buy
TRC B118728 Bassianolide 64763-82-2 1mg $690 2021-12-16 Buy
Product number Packaging Price Buy
22001 500μg $311 Buy
22001 2.5mg $1394 Buy
B118728 1mg $690 Buy

bassianolide Chemical Properties,Uses,Production

Uses

Bassianolide is a cyclooctadepsipeptide insecticide isolated from the entomopathogenic fungi, Beauveria and Verticillium lecanii, first reported by researchers at University of Tokyo in 1978. Bassianolide is related to the insecticidal and nematocidal actives, PF1022 complex and the synthetic anthelminthic emodepside. While the mode of action of bassianolide is not fully resolved, it is thought to act on ion channels at the level of the neuromuscular junction, like emodepside. Bassianolide is one of the active components of Beauveria bassiana biocontrol products.

Definition

ChEBI: Bassianolide is a cyclodepsipeptide consisting of a cyclic tetramer of the depsipeptide D-Hiv-N-methyl-L-leucine (where D-Hiv = D-alpha-hydroxyisovaleric acid). Found in the fungal species Beauveria bassiana and Verticillium lecanii, it has insecticidal properties and is used as a commercial biopesticide to control of insects of agricultural, veterinary and medical significance. For elucidation of the structure, see Suzuki et al., Tetrahedron Lett. 1977 v25, 2167-2170. It has a role as an antineoplastic agent, an insecticide and a fungal metabolite. It is a cyclodepsipeptide and a cyclooctadepsipeptide.

bassianolide Preparation Products And Raw materials

Raw materials

Preparation Products

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bassianolide Cyclo[D-Hmb-N-methyl-L-Leu-D-Hmb-N-methyl-L-Leu-D-Hmb-N-methyl-L-Leu-D-Hmb-N-methyl-L-Leu-] BASSIANOLIDE,>95% BY HPLC 4,10,16,22-tetramethyl-3,9,15,21-tetrakis(2-methylpropyl)-6,12,18,24-tetra(propan-2-yl)-1,7,13,19-tetraoxa-4,10,16,22-tetraazacyclotetracosane-2,5,8,11,14,17,20,23-octone Cyclo[(2R)-2-hydroxy-3-methylbutanoyl-N-methyl-L-leucyl-(2R)-2-hydroxy-3-methylbutanoyl-N-methyl-L-leucyl-(2R)-2-hydroxy-3-methylbutanoyl-N-methyl-L-leucyl-(2R)-2-hydroxy-3-methylbutanoyl-N-methyl-L-leucyl] (-)-Bassianolide 4,10,16,22-tetramethyl-3,9,15,21-tetrakis(2-methylpropyl)-6,... 64763-82-2 4763-82-2 C48H84N4O12