Adenosine 5'-methylenediphosphate (sodium salt)
- CAS No.
- 2659222-76-9
- Chemical Name:
- Adenosine 5'-methylenediphosphate (sodium salt)
- Synonyms
- Adenosine 5'-methylenediphosphate (sodium salt)
- CBNumber:
- CB613503312
- Molecular Formula:
- C11H18N5NaO9P2
- Molecular Weight:
- 449.23
- MDL Number:
- MOL File:
- 2659222-76-9.mol
Adenosine 5'-methylenediphosphate (sodium salt) Chemical Properties,Uses,Production
Uses
MethADP (Adenosine 5'-(α,β-methylene)diphosphate) trisodium is a CD73 inhibitor. MethADP trisodium can be used for the research of ATP-adenosine pathway[1].
References
[1] Mohlin C, et al. Studies of the extracellular ATP-adenosine pathway in human urinary tract epithelial cells. Pharmacology. 2009;84(4):196-202. DOI:10.1159/000235908
[2] BRUNS R F. Adenosine receptor activation by adenine nucleotides requires conversion of the nucleotides to adenosine.[J]. Naunyn-Schmiedeberg’s archives of pharmacology, 1980, 315 1: 5-13. DOI: 10.1007/bf00504224
[3] ELIZANDRA BRAGANHOL . Ecto-5′-nucleotidase/CD73 inhibition by quercetin in the human U138MG glioma cell line[J]. Biochimica et biophysica acta. General subjects, 2007, 1770 9: Pages 1352-1359. DOI: 10.1016/j.bbagen.2007.06.003
[4] SHALAIMAITI SHALI. Ecto-5′-nucleotidase (CD73) is a potential target of hepatocellular carcinoma[J]. Journal of Cellular Physiology, 2018, 234 7: 10248-10259. DOI: 10.1002/jcp.27694
[5] GIOVANNI FORTE. Inhibition of CD73 improves B cell-mediated anti-tumor immunity in a mouse model of melanoma.[J]. Journal of immunology, 2012, 189 5: 2226-2233. DOI: 10.4049/jimmunol.1200744
Adenosine 5'-methylenediphosphate (sodium salt) Preparation Products And Raw materials
Raw materials
Preparation Products
Adenosine 5'-methylenediphosphate (sodium salt) Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shanghai Yifei Biotechnology Co. , Ltd. | 021-65675885 18964387627 | customer_service@efebio.com | China | 11973 | 58 |
| Cayman Chemical Company | 800-364-9897 | sales@caymanchem.com | China | 6838 | 58 |
| Supplier | Advantage |
|---|---|
| Shanghai Yifei Biotechnology Co. , Ltd. | 58 |
| Cayman Chemical Company | 58 |
