Biotin-PEG4-carboxylicacid

Description

Biotin-PEG4-carboxylic acid is a bifunctional tetraethyleneglycol derivative bearing a carboxy group and biotin moiety. The carboxy group can be activated with peptide coupling reagents like PyBOP or carbodiimides like EDC to form a stable amide linkage with amines. Biotin-labeled biomolecules can be bound to avidin or streptavidin for further purification and detection.

The structure of this reagent features a long hydrophilic PEG4 linker that separates biotin residue from the target molecule for efficient binding with streptavidin. The linker also enhances aqueous solubility to facilitate conjugation.