ANTI-AQUAPORIN 2
- CAS No.
- Chemical Name:
- ANTI-AQUAPORIN 2
- Synonyms
- ANTI-MCH-CD;ANTI-AQP-CD;ANTI-AQUAPORIN 2;ANTI-WATER CHANNEL AQUAPORIN 2;Anti-Water Channel Aquaporin 2 antibody produced in rabbit
- CBNumber:
- CB6142986
- Molecular Formula:
- Molecular Weight:
- 381.28
- MDL Number:
- MFCD02262543
- MOL File:
- Mol file
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS06 |
|---|---|
| Signal word | Danger |
| Hazard statements | H302+H332-H311-H412 |
| Precautionary statements | P273-P280-P301+P312+P330-P302+P352+P312-P304+P340+P312 |
| Hazard Codes | T |
| Risk Statements | 25-32-52/53 |
| Safety Statements | 45-61 |
| WGK Germany | 3 |
ANTI-AQUAPORIN 2 price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | A7310 | Anti-Water Channel Aquaporin 2 antibody produced in rabbit IgG fraction of antiserum, lyophilized powder | 0.05ML | $555 | 2024-03-01 | Buy | |
| Sigma-Aldrich | A7310 | Anti-Water Channel Aquaporin 2 antibody produced in rabbit IgG fraction of antiserum, lyophilized powder | 0.2ML | $1060 | 2024-03-01 | Buy | |
| American Custom Chemicals Corporation | ATB0018545 | ANTI-AQUAPORIN 2 95.00% | 5MG | $495.32 | 2021-12-16 | Buy |
ANTI-AQUAPORIN 2 Chemical Properties,Uses,Production
Uses
Anti-Water Channel Aquaporin 2 antibody is also suitable for use in chemiluminescent western blot (1:200-1:1000), and immunoblot.
General Description
Aquaporin 2 (AQP2) is a water channel protein that regulates water balance in renal connecting tubules and collecting ducts. AQP2 is activated by anti-diuretic hormone and subsequently facilitates water inflow in renal cells. This protein also interacts with integrin to modulate epithelial cell morphogenesis and cell movement . Anti-Water Channel Aquaporin 2 antibody recognizes aquaporin 2 from rat by immunoblotting. The antibody also reacts with mouse and human AQP2.
Biochem/physiol Actions
Aquaporin (AQP2) N-terminal region plays a key role in trafficking. The C-terminal phosphorylation is crucial for the water permeability function of the apical membrane. Also, ubiquitination at lysine 270 is needed for AQP2 sorting and degradation in lysosomes or elimination through exosomes. Mutation in AQP2 gene is implicated in congenital nephrogenic diabetes insipidus (NDI), a water balance disorder. The functional dysregulation of AQP2 is also correlated to preeclampsia, congestive heart failure and liver cirrhosis.
ANTI-AQUAPORIN 2 Preparation Products And Raw materials
Raw materials
Preparation Products
ANTI-AQUAPORIN 2 Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Sigma-Aldrich | 021-61415566 800-8193336 | orderCN@merckgroup.com | China | 51471 | 80 |
| Supplier | Advantage |
|---|---|
| Sigma-Aldrich | 80 |