Carebastine-d5
- CAS No.
- 1189661-02-6
- Chemical Name:
- Carebastine-d5
- Synonyms
- Carebastine-d5;Valine Impurity 136;4-[4-[4-(DiphenylMethoxy-d5)-1-piperidinyl]-1-oxobutyl]-α,α-diMethylbenzeneacetic Acid;4-[4-[4-(Diphenylmethoxy-d5)-1-piperidinyl]-1-oxobutyl]-a,a-dimethylbenzeneacetic Acid;4-[4-[4-(Diphenylmethoxy-d5)-1-piperidinyl]-1-oxobutyl]-α,a-dimethylbenzeneacetic Acid
- CBNumber:
- CB61565757
- Molecular Formula:
- C32H37NO4
- Molecular Weight:
- 499.64048
- MDL Number:
- MFCD11977981
- MOL File:
- 1189661-02-6.mol
Last updated:2023-05-18 11:31:13
Carebastine-d5 price More Price(8)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Cayman Chemical | 30755 | Carebastine-d5 | 1189661-02-6 | 1mg | $275 | 2024-03-01 | Buy |
| TRC | C183442 | Carebastine-d5 | 1189661-02-6 | 1mg | $220 | 2021-12-16 | Buy |
| Usbiological | 005778 | Carebastine-d5 | 1189661-02-6 | 1mg | $502 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | RDL0006701 | CAREBASTINE-D5 95.00% | 1189661-02-6 | 1MG | $785.4 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | RDL0006701 | CAREBASTINE-D5 95.00% | 1189661-02-6 | 2.5MG | $1180 | 2021-12-16 | Buy |
Carebastine-d5 Chemical Properties,Uses,Production
Description
Carebastine-d5 is intended for use as an internal standard for the quantification of carebastine by GC- or LC-MS. Carebastine is an active metabolite of ebastine and a histamine H1 receptor antagonist (Ki = 75.86 nM). It inhibits histamine-induced contraction of isolated guinea pig trachea (IC50 = 120 nM). It also inhibits histamine release from isolated rat peritoneal mast cells and human basophils when used at concentrations ranging from 30 to 100 μM. Carebastine decreases production of chemokine (C-C motif) ligand 5 (CCL5) and CCL2 in human nasal epithelial cells isolated from patients with nasal allergies.
Chemical Properties
Off-White Solid
Uses
The active labelled carboxylic acid metabolite of Ebastine.
Carebastine-d5 Preparation Products And Raw materials
Raw materials
Preparation Products
Carebastine-d5 Suppliers
Global( 24)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Chemsky（shanghai）International Co.,Ltd. | 021-50135380 | shchemsky@sina.com | China | 32344 | 50 |
| Cato Research Chemicals Inc. | 020-81960175 | min.he@cato-chem.com | China | 1958 | 55 |
| Energy Chemical | 021-58432009 400-005-6266 | marketing1@energy-chemical.com | China | 44894 | 58 |
| Foshan Treasure Biotechnology Co., Ltd | 0757-85921206 18520245316 | 2329783215@qq.com | China | 12664 | 58 |
| ChemeGen 中国 | 18818260767 | sales@chemegen.com | China | 6975 | 58 |
| Shanghai Yiyan Biotechnology Co. , Ltd. | 021-69985186 13611928337 | 3427709316@qq.com | China | 7984 | 58 |
| Shanghai isotope chemical co.,ltd | 021-021-51600108 13062666369 | sales@chinaisotope.com | China | 4272 | 58 |
| Shanghai Yifei Biotechnology Co. , Ltd. | 021-65675885 18964387627 | customer_service@efebio.com | China | 8740 | 58 |
| guoyungurui | 18162595016 | 3287908757@qq.com | China | 10015 | 58 |
| Nanjing Shizhou Biology Technology Co.,Ltd | 17301488900 | judy.xia@synzest.com | China | 13698 | 58 |
4-[4-[4-(Diphenylmethoxy-d5)-1-piperidinyl]-1-oxobutyl]-α,a-dimethylbenzeneacetic Acid
Carebastine-d5
4-[4-[4-(Diphenylmethoxy-d5)-1-piperidinyl]-1-oxobutyl]-a,a-dimethylbenzeneacetic Acid
4-[4-[4-(DiphenylMethoxy-d5)-1-piperidinyl]-1-oxobutyl]-α,α-diMethylbenzeneacetic Acid
Valine Impurity 136
1189661-02-6
C32H32D5NO4
Intermediates & Fine Chemicals
Isotope Labeled Compounds
Metabolites & Impurities
Pharmaceuticals
Isotope Labelled Compounds