ChemicalBook >> CAS DataBase List >>Cl-Amidine
Cl-Amidine
- CAS No.
- 913723-61-2
- Chemical Name:
- Cl-Amidine
- Synonyms
- Cl-Amidine;N-BCl-I-OA cpd;Cl amidine,Clamidine;N-alpha-Benzoyl-N5-(2-chloro-1-iminoethyl)-1-ornithine amide;N-[(1S)-1-(Aminocarbonyl)-4-[(2-chloro-1-iminoethyl)amino]butyl]benzamide;Benzamide, N-[(1S)-1-(aminocarbonyl)-4-[(2-chloro-1-iminoethyl)amino]butyl]-;N-[(1S)-1-(Aminocarbonyl)-4-[(2-chloro-1-iminoethyl)amino]butyl]-benzamideN-
- CBNumber:
- CB62590660
- Molecular Formula:
- C14H19ClN4O2
- Molecular Weight:
- 310.78
- MDL Number:
- MFCD20278255
- MOL File:
- 913723-61-2.mol
- MSDS File:
- SDS
Last updated:2023-05-21 10:59:17
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H335 |
| Precautionary statements | P280-P305+P351+P338 |
Cl-Amidine Chemical Properties,Uses,Production
Definition
ChEBI: Cl-Amidine is a member of benzenes.
Biological Activity
Cl-amidine is an orally active PAD inhibitor with IC50 values of 0.8 μM, 6.2 μM and 5.9 μM for PAD1, PAD3 and PAD4, respectively.It induces apoptosis in cancer cells. And Cl-Amidine blocks histone 3 citrullination and neutrophil extracellular trap formation and improves survival in mice with sepsis.
target
IC50: 0.8 μM (PAD1), 5.9 μM (PAD4), 6.2 μM (PAD3).
Cl-Amidine Preparation Products And Raw materials
Raw materials
Preparation Products
Cl-Amidine Suppliers
Global( 37)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 19892 | 58 |
| InvivoChem | +1-708-310-1919 +1-13798911105 | sales@invivochem.cn | United States | 6393 | 58 |
| Shanghai Boyle Chemical Co., Ltd. | sales@boylechem.com | China | 2923 | 55 | |
| ShangHai Biochempartner Co.,Ltd | 17754423994 17754423994 | 2853530910@QQ.com | China | 8011 | 62 |
| Shanghai Biopharmaleader Co., Ltd. | +86 18721201413 | sales@biopharmaleader.com | China | 1720 | 58 |
| Twochem Co.Ltd. | 021-58111628 15800915896 | China | 1988 | 58 | |
| Fan De(Beijing) Biotechnology Co., Ltd. | 15911056312 | liming@bio-fount.com | China | 9730 | 58 |
| Shanghai zhigan biotechnology co., LTD | zhiqianbio@126.com | China | 19785 | 58 | |
| Tianjin Kaifu Pharmaceutical Technology Co., Ltd. | 18081075745 | chemflowtech@sina.com | China | 1886 | 58 |
| Nanjing Meihao Pharmaceutical Technology Co., Ltd. | meitaochem@126.com | meitaochem@126.com | China | 19105 | 58 |
Cl-Amidine
N-[(1S)-1-(Aminocarbonyl)-4-[(2-chloro-1-iminoethyl)amino]butyl]-benzamideN-
N-[(1S)-1-(Aminocarbonyl)-4-[(2-chloro-1-iminoethyl)amino]butyl]benzamide
N-alpha-Benzoyl-N5-(2-chloro-1-iminoethyl)-1-ornithine amide
Benzamide, N-[(1S)-1-(aminocarbonyl)-4-[(2-chloro-1-iminoethyl)amino]butyl]-
Cl amidine,Clamidine
N-BCl-I-OA cpd
913723-61-2