Propargyl-PEG5-amine
- CAS No.
- 1589522-46-2
- Chemical Name:
- Propargyl-PEG5-amine
- Synonyms
- Alkyne-PEG5-NH2;HC≡C-CH2-PEG6-NH2;PROPARGYL-PEG5-NH2;Propargyl-PEG5-amine;3,6,9,12,15-Pentaoxaoctadec-17-yn-1-amine;Propargyl-PEG5-NH2/3,6,9,12,15-Pentaoxaoctadec-17-yn-1-amine;2-[2-[2-[2-(2-prop-2-ynoxyethoxy)ethoxy]ethoxy]ethoxy]ethanamine
- CBNumber:
- CB63062630
- Molecular Formula:
- C13H25NO5
- Molecular Weight:
- 275.34
- MDL Number:
- MFCD27977505
- MOL File:
- 1589522-46-2.mol
SAFETY
Risk and Safety Statements
Symbol(GHS) | GHS07 |
---|---|
Signal word | Warning |
Hazard statements | H302-H312-H332 |
Precautionary statements | P261-P264-P270-P271-P280-P301+P312-P302+P352-P304+P340-P330-P363-P501 |
Propargyl-PEG5-amine price More Price(5)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
BroadPharm | BP-22103 | Propargyl-PEG5-amine 98% | 1589522-46-2 | 500mg | $680 | 2021-12-16 | Buy |
Apolloscientific | BIPG1726 | Propargyl-PEG5-amine | 1589522-46-2 | 250mg | $759 | 2021-12-16 | Buy |
BroadPharm | BP-22103 | Propargyl-PEG5-amine 98% | 1589522-46-2 | 1g | $1020 | 2021-12-16 | Buy |
Acrotein | B-1144 | Propargyl-PEG5-NH2 97% | 1589522-46-2 | 0.25g | $201.66 | 2021-12-16 | Buy |
Acrotein | B-1144 | Propargyl-PEG5-NH2 97% | 1589522-46-2 | 0.5g | $302.5 | 2021-12-16 | Buy |
Propargyl-PEG5-amine Chemical Properties,Uses,Production
Description
Propargyl-PEG5-amine is a propargyl linker that is commonly used as a Click Chemistry reagent for copper-catalyzed reactions with azides. The amine moiety reacts with carboxylic acids, activated NHS esters and other carbonyl compounds. The PEG spacer helps improve the water solubility of the molecule in aqueous media.
Biological Activity
Propargyl-PEG5-amine is a non-cleavable ADC linker for the synthesis of antibody drug conjugates (ADCs). It is a PROTAC linker belonging to the PEG class and can be used to synthesize a series of PROTAC molecules.
in vitro
ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
target
Non-cleavable < span> | PEGs
|
Propargyl-PEG5-amine Preparation Products And Raw materials
Raw materials
Preparation Products
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
airuikechemical co., ltd. | +undefined86-15315557071 | sales02@sdzhonghuimaterial.com | China | 983 | 58 |
Chongqing Chemdad Co., Ltd | +86-023-6139-8061 +86-86-13650506873 | sales@chemdad.com | China | 39916 | 58 |
Zhengzhou Alfa Chemical Co.,Ltd | +8618530059196 | sale04@alfachem.cn | China | 13349 | 58 |
TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 19892 | 58 |
Wuhan Borenpharm Co., Ltd | 027-65563561 18717150066 | 3207347307@qq.com | CHINA | 1238 | 58 |
Hangzhou Huarong Pharm Co., Ltd. | 571-86758373 +8613588754946 | sales@huarongpharm.com | CHINA | 3149 | 58 |
Nantong HI-FUTURE Biology Co., Ltd. | +undefined18051384581 | sales@chemhifuture.com | China | 3136 | 58 |
Wuhan Topule Biopharmaceutical Co., Ltd | +8618327326525 | masar@topule.com | China | 8474 | 58 |
Jilin Chinese Academy of Sciences-yanshen Technology | +undefined18143011203 | info@chemextension.com | China | 42057 | 58 |
Xian confluore Biological Technology Co., Ltd. | +86-15680926068 +86-15680926068 | 1924344760@confluore.cn | China | 2996 | 58 |
View Lastest Price from Propargyl-PEG5-amine manufacturers
Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
---|---|---|---|---|---|---|---|---|
2024-04-08 | Propargyl-PEG5-amine
1589522-46-2
|
US $0.00-0.00 / Kg | 1Kg | 99.9% | 200tons | airuikechemical co., ltd. | ||
2024-03-26 | Propargyl-PEG5-amine
1589522-46-2
|
US $0.00 / g | 5g | >98.00% | 5g | Xian confluore Biological Technology Co., Ltd. |
- Propargyl-PEG5-amine
1589522-46-2
- US $0.00-0.00 / Kg
- 99.9%
- airuikechemical co., ltd.
- Propargyl-PEG5-amine
1589522-46-2
- US $0.00 / g
- >98.00%
- Xian confluore Biological Technology Co., Ltd.
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