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4-(Boc-aminomethyl)aniline

4-(Boc-aminomethyl)aniline structure

CAS No.: 94838-55-8

Chemical Name:: 4-(Boc-aminomethyl)aniline

Synonyms: 4-[(N-Boc)aminomethyL;4-(BOC-AMINOMETHYL)-ANILINE;4-(N-boc-aminomethyl)anline;4-(N-BOC-AMINOMETHYL)ANILINE;4-[(N-tert-Butyloxycarbonyl)aMi;4-[(N-Boc)aMinoMethyl]aniline 97%;TERT-BUTYL (4-AMINOBENZYL)CARBAMATE;4-[(N-Boc)aminomethyl]aniline;(4-aminobenzyl)(tert-butyl)carbamate;TERT-BUTYL N-(4-AMINOBENZYL)CARBAMATE

CBNumber:: CB6395849

Molecular Formula:: C12H18N2O2

Molecular Weight:: 222.28

MDL Number:: MFCD03001716

MOL File:: 94838-55-8.mol

MSDS File:: SDS

Last updated:2025-08-08 17:45:00

Product description	Number	Pack Size	Price
4-[(N-Boc)aminomethyl]aniline 97%	525626	1g	$65.83
4-(N-Boc-aminomethyl)aniline	B619800	1g	$155
4-(N-BOC-AMINOMETHYL)ANILINE 95.00%	CHM0024763	1G	$172.2
4-(N-Boc-aminomethyl)aniline	FB18927	10g	$185
tert-Butyl N-(4-aminobenzyl)carbamate >95%	046294	500mg	$244
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4-(Boc-aminomethyl)aniline Properties

Melting point	75-78 °C(lit.)
Boiling point	382.3±25.0 °C(Predicted)
Density	1.095±0.06 g/cm3(Predicted)
storage temp.	Keep in dark place,Sealed in dry,Room Temperature
pka	12.62±0.46(Predicted)
form	Crystalline Powder
color	White to tan
InChI	InChI=1S/C12H18N2O2/c1-12(2,3)16-11(15)14-8-9-4-6-10(13)7-5-9/h4-7H,8,13H2,1-3H3,(H,14,15)
InChIKey	UXWQXBSQQHAGMG-UHFFFAOYSA-N
SMILES	C(OC(C)(C)C)(=O)NCC1=CC=C(N)C=C1
CAS DataBase Reference	94838-55-8(CAS DataBase Reference)
UNSPSC Code	12352100
NACRES	NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS07
Signal word	Warning
Hazard statements	H315-H319-H335
Precautionary statements	P261-P264-P271-P280-P302+P352-P305+P351+P338
Hazard Codes	Xi
Risk Statements	36/37/38
Safety Statements	26-36
WGK Germany	3
HazardClass	IRRITANT
HS Code	29242990

4-(Boc-aminomethyl)aniline price More Price(26)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	525626	4-[(N-Boc)aminomethyl]aniline 97%	94838-55-8	1g	$65.83	2025-07-31	Buy
TRC	B619800	4-(N-Boc-aminomethyl)aniline	94838-55-8	1g	$155	2021-12-16	Buy
American Custom Chemicals Corporation	CHM0024763	4-(N-BOC-AMINOMETHYL)ANILINE 95.00%	94838-55-8	1G	$172.2	2021-12-16	Buy
Biosynth Carbosynth	FB18927	4-(N-Boc-aminomethyl)aniline	94838-55-8	10g	$185	2021-12-16	Buy
Matrix Scientific	046294	tert-Butyl N-(4-aminobenzyl)carbamate >95%	94838-55-8	500mg	$244	2021-12-16	Buy

Product number	Packaging	Price	Buy
525626	1g	$65.83	Buy
B619800	1g	$155	Buy
CHM0024763	1G	$172.2	Buy
FB18927	10g	$185	Buy
046294	500mg	$244	Buy

4-(Boc-aminomethyl)aniline Chemical Properties,Uses,Production

Chemical Properties

White solid

Uses

4-[(N-Boc)aminomethyl]aniline may be used in the synthesis of haptens and 4-(N-boc-aminomethyl)benzene diazonium tetrafluoroborate salt.

Uses

An aniline derivative, 4-(Boc-aminomethyl)aniline can be used in the preparation of various organic synthase inhibitors and other bio-active compounds.

General Description

4-[(N-Boc)aminomethyl]aniline is a protected amine.

Synthesis

94838-58-1

94838-55-8

General procedure for the synthesis of 4-(N-BOC-aminomethyl)aniline from N-Boc-4-nitrophenylethylamine: 10% Pd/C catalyst (62 mg) was added to a solution of N-Boc-4-nitrophenylethylamine (590 mg, 2.33 mmol) in methanol (20.6 mL). The reaction mixture was subjected to hydrogenation under 35 psi hydrogen pressure for 2 hours at room temperature. Upon completion of the reaction, the catalyst was removed by filtration and the filtrate was evaporated. The residue was purified by silica gel column chromatography using ethyl acetate with hexane (1:1) as eluent to afford 4-(N-BOC-aminomethyl)aniline (520 mg, 100% yield) as an oil.1H NMR (DMSO-d6): δ 1.37 (s, 9H), 3.91 (d, J=6.0 Hz, 2H), 4.90 (s, 2H disappeared after D2O exchange), 6.47 (d, J=8.1Hz, 2H), 6.87 (d, J=8.0Hz, 2H), 7.13ppm (s, 1H, disappeared after D2O exchange).IR: ν1695, 2974 cm-1.

References

[1] European Journal of Medicinal Chemistry, 2014, vol. 80, p. 101 - 111
[2] Journal of Medicinal Chemistry, 2003, vol. 46, # 5, p. 691 - 701
[3] Patent: US2009/54395, 2009, A1. Location in patent: Page/Page column 48
[4] Chemical Communications, 2014, vol. 50, # 97, p. 15305 - 15308
[5] Bioorganic and Medicinal Chemistry Letters, 2000, vol. 10, # 6, p. 553 - 557

4-(Boc-aminomethyl)aniline Preparation Products And Raw materials

Raw materials

TERT-BUTYL (4-NITROBENZYL)CARBAMATE Di-tert-butyl dicarbonate 4-Aminobenzylamine Hydrogen Palladium

Methanol Activated carbon

1of2

Preparation Products

4-(Boc-aminomethyl)aniline Suppliers

Global( 161)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
career henan chemical co	+86-0371-86658258 +8613203830695	sales@coreychem.com	China	29847	58
Accela ChemBio Inc.	+1-858-6993322	info@accelachem.com	United States	21193	58
Hubei xin bonus chemical co. LTD	86-13657291602	linda@hubeijusheng.com	CHINA	22963	58
Alchem Pharmtech,Inc.	8485655694	sales@alchempharmtech.com	United States	63687	58
CONIER CHEM AND PHARMA LIMITED	+8618523575427	sales@conier.com	China	49975	58
Guangzhou Yuheng Pharmaceutical Technology Co., Ltd	+8613580539051	joe@yuhengpharm.com	CHINA	21142	58
Shanghai UCHEM Inc.	+862156762820 +86-13564624040	sales@myuchem.com	China	8460	58
Dideu Industries Group Limited	+86-29-89586680 +86-15129568250	1026@dideu.com	China	20284	58
Zhejiang J&C Biological Technology Co.,Limited	+1-2135480471	sales@sarms4muscle.com	China	10473	58
Labnetwork lnc.	+86-27-50766799 +8618062016861	contact@labnetwork.com	China	19987	58

Supplier	Advantage
career henan chemical co	58
Accela ChemBio Inc.	58
Hubei xin bonus chemical co. LTD	58
Alchem Pharmtech,Inc.	58
CONIER CHEM AND PHARMA LIMITED	58
Guangzhou Yuheng Pharmaceutical Technology Co., Ltd	58
Shanghai UCHEM Inc.	58
Dideu Industries Group Limited	58
Zhejiang J&C Biological Technology Co.,Limited	58
Labnetwork lnc.	58

View Lastest Price from 4-(Boc-aminomethyl)aniline manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2025-11-18	4-(Boc-aminomethyl)aniline 94838-55-8	US $1.10 / g	1g	99.00%	100 Tons Min	Dideu Industries Group Limited
2024-03-06	4-(N-Boc-Aminomethyl)aniline 94838-55-8	US $800.00 / g	1g	98	500 Kg	R&D Scientific Inc.
2019-07-06	4-(N-BOC-AMINOMETHYL)ANILINE 94838-55-8	US $1.00 / KG	1KG	99%	1000KG	Career Henan Chemical Co

4-(Boc-aminomethyl)aniline
94838-55-8
US $1.10 / g
99.00%
Dideu Industries Group Limited

4-(N-Boc-Aminomethyl)aniline
94838-55-8
US $800.00 / g
98
R&D Scientific Inc.

4-(N-BOC-AMINOMETHYL)ANILINE
94838-55-8
US $1.00 / KG
99%
Career Henan Chemical Co

4-(Boc-aminomethyl)aniline Spectrum

4-(Boc-aminomethyl)aniline(94838-55-8)¹HNMR

94838-55-8(4-(Boc-aminomethyl)aniline)Related Search:

3-(BOC-AMINOMETHYL)ANILINE

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