BMS-955176
- CAS No.
- 1392312-45-6
- Chemical Name:
- BMS-955176
- Synonyms
- GSK3532795;BMS-955176;BMS-955176(free base);GSK-3532795,GSK3532795;BMS-955176 (GSK-3532795;Benzoic acid, 4-[17-[[2-(1,1-dioxido-4-thiomorpholinyl)ethyl]amino]-28-norlupa-2,20(29)-dien-3-yl]-
- CBNumber:
- CB64667669
- Molecular Formula:
- C42H62N2O4S
- Molecular Weight:
- 691.02
- MDL Number:
- MFCD32062754
- MOL File:
- 1392312-45-6.mol
| Boiling point | 780.7±60.0 °C(Predicted) |
|---|---|
| Density | 1.19±0.1 g/cm3(Predicted) |
| solubility | DMSO:0.0(Max Conc. mg/mL);0.0(Max Conc. mM) |
| pka | 4.36±0.10(Predicted) |
| form | Solid |
| color | White to off-white |
| FDA UNII | 4CA9IAU7RJ |
BMS-955176 Chemical Properties,Uses,Production
Uses
GSK3532795 (BMS-955176) is a potent, orally active, second-generation HIV-1 maturation inhibitor, with EC50s of 1.9, 10.2, 2.7 and 13 nM for HIV-1 WT, HIV-1 WT(human serum), HIV-1 V370A, and HIV-1 ΔV370, respectively[1].
IC 50
HIV-1
References
[1] Regueiro-Ren A, et al. Design, Synthesis, and SAR of C-3 Benzoic Acid, C-17 Triterpenoid Derivatives. Identification of the HIV-1 Maturation Inhibitor 4-((1 R,3a S,5a R,5b R,7a R,11a S,11b R,13a R,13b R)-3a-((2-(1,1-Dioxidothiomorpholino)ethyl)amino)-5a,5b,8,8,11a-pentamethyl-1-(prop-1-en-2-yl)-2,3,3a,4,5,5a,5b,6,7,7a,8,11,11a,11b,12,13,13a,13b-octadecahydro-1 H-cyclopenta[ a]chrysen-9-yl)benzoic Acid (GSK3532795, BMS-955176). J Med Chem. 2018 Aug 23;61(16):7289-7313. DOI:10.1021/acs.jmedchem.8b00854
BMS-955176 Preparation Products And Raw materials
Raw materials
Preparation Products
BMS-955176 Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| TargetMol Chemicals Inc. | +1-781-999-5354; +17819995354 | marketing@targetmol.com | United States | 32435 | 58 |
| HANGZHOU CLAP TECHNOLOGY CO.,LTD | 86-571-88216897,88216896 13588875226 | sales@hzclap.com | CHINA | 6312 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354; | support@targetmol.com | United States | 39035 | 58 |
| HANGZHOU LEAP CHEM CO., LTD. | +86-571-87711850 | market18@leapchem.com | China | 43339 | 58 |
| TargetMol Chemicals Inc. | +17819995354 | marketing@targetmol.com | United States | 19961 | 58 |
| BOC Sciences | 1-631-485-4226; 16314854226 | info@bocsci.com | United States | 12952 | 65 |
| ShangHai Caerulum Pharma Discovery Co., Ltd. | 18149758185 | sales-cpd@caerulumpharma.com | China | 3506 | 58 |
| Fan De(Beijing) Biotechnology Co., Ltd. | 15911056312 | liming@bio-fount.com | China | 9729 | 58 |
| TargetMol Chemicals Inc. | 4008200310 | marketing@tsbiochem.com | China | 24961 | 58 |
| ShangHai Caerulum Pharma Discovery Co., Ltd. | 15000803246 18149758185 | sales-cpd@caerulumpharma.com | China | 425 | 58 |
View Lastest Price from BMS-955176 manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2025-08-21 | GSK3532795
1392312-45-6
|
US $1970.00-3400.00 / mg | 10g | TargetMol Chemicals Inc. | |||
 |
2025-07-22 | GSK3532795
1392312-45-6
|
US $1970.00-3400.00 / mg | 10g | TargetMol Chemicals Inc. |
-
- GSK3532795
1392312-45-6
- US $1970.00-3400.00 / mg
- TargetMol Chemicals Inc.
-
- GSK3532795
1392312-45-6
- US $1970.00-3400.00 / mg
- TargetMol Chemicals Inc.
