ChemicalBook >> CAS DataBase List >>Mcl1-IN-12
Mcl1-IN-12
- CAS No.
- 2042211-12-9
- Chemical Name:
- Mcl1-IN-12
- Synonyms
- Mcl1-IN-12;Benzamide, N-[4-[[[[3-nitro-4-[[2-(phenylthio)ethyl]amino]phenyl]sulfonyl]amino]carbonyl]phenyl]-4-[1-(5,6,7,8-tetrahydro-3,5,5,8,8-pentamethyl-2-naphthalenyl)ethenyl]-
- CBNumber:
- CB65821219
- Molecular Formula:
- C45H46N4O6S2
- Molecular Weight:
- 803
- MDL Number:
- MFCD32174236
- MOL File:
- 2042211-12-9.mol
Last updated:2025-04-18 09:52:31
Mcl1-IN-12 Chemical Properties,Uses,Production
Uses
Mcl1-IN-12 (Compound F) is a selective Mcl-1 inhibitor, less potent at Bcl-2, with Kis of 0.29 and 3.1 μM, respectively. Anti-tumor activity[1].
References
[1] Wang M, et al. Design, synthesis, and activity evaluation of selective inhibitors of anti-apoptotic Bcl-2 proteins: The effects on the selectivity of the P1 pockets in the active sites. Bioorg Med Chem Lett. 2016 Nov 1;26(21):5207-5211. DOI:10.1016/j.bmcl.2016.09.061
Mcl1-IN-12 Preparation Products And Raw materials
Raw materials
Preparation Products
Mcl1-IN-12 Suppliers
Global( 5)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| TargetMol Chemicals Inc. | +1-781-999-5354; +17819995354 | marketing@targetmol.com | United States | 32435 | 58 |
| Fan De(Beijing) Biotechnology Co., Ltd. | 15911056312 | liming@bio-fount.com | China | 9729 | 58 |
| cjbscvictory | 13348960310 | 3003867561@qq.com | China | 10505 | 58 |
| TargetMol Chemicals Inc. | 15002134094 | marketing@targetmol.cn | China | 29567 | 58 |
| Adooq Bioscience LLC | 400-025-6535 | sales@adooq.cn | China | 6215 | 58 |
| Supplier | Advantage |
|---|---|
| TargetMol Chemicals Inc. | 58 |
| Fan De(Beijing) Biotechnology Co., Ltd. | 58 |
| cjbscvictory | 58 |
| TargetMol Chemicals Inc. | 58 |
| Adooq Bioscience LLC | 58 |
Mcl1-IN-12
Benzamide, N-[4-[[[[3-nitro-4-[[2-(phenylthio)ethyl]amino]phenyl]sulfonyl]amino]carbonyl]phenyl]-4-[1-(5,6,7,8-tetrahydro-3,5,5,8,8-pentamethyl-2-naphthalenyl)ethenyl]-
2042211-12-9
C45H46N4O6S2
